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Sublingual Sufentanil Attenuates Perceived Pain, But Not Blood Pressure Responses, During A Cold Pressor Test, Caitlin P. Jarrard, Zachary J. Mckenna, Whitley C. Atkins, Josh Foster, Joseph C. Watso, Craig G. Crandall
Sublingual Sufentanil Attenuates Perceived Pain, But Not Blood Pressure Responses, During A Cold Pressor Test, Caitlin P. Jarrard, Zachary J. Mckenna, Whitley C. Atkins, Josh Foster, Joseph C. Watso, Craig G. Crandall
International Journal of Exercise Science: Conference Proceedings
Sublingual sufentanil was developed to reduce pain following a traumatic injury in the field (e.g., battlefield). However, it is unknown whether an analgesic dose of sufentanil affects cardiovascular responses to a painful stimulus in humans. PURPOSE: We tested the hypothesis that sublingual sufentanil blunts pain perception and the accompanying cardiovascular responses during a cold pressor test (CPT). METHODS: Twenty-nine adults, 15 males and 14 females (age: 29 ± 5 years, body mass: 74 ± 8 kg, body mass index: 25 ± 2 kg/m2) participated in this double-blind, randomized, crossover, placebo-controlled trial. Following sublingual administration of sufentanil (30 µg) …
Can We Calculate Mean Arterial Pressure In Humans?, Matthew M. Howrey, Tiffany L. Brazile, Bryce N. Balmain, Andrew R. Tomlinson, James P. Macnamara, Tony G. Babb, Benjamin D. Levine, Satyam Sarma, Christopher M. Hearon Jr, Denis J. Wakeham
Can We Calculate Mean Arterial Pressure In Humans?, Matthew M. Howrey, Tiffany L. Brazile, Bryce N. Balmain, Andrew R. Tomlinson, James P. Macnamara, Tony G. Babb, Benjamin D. Levine, Satyam Sarma, Christopher M. Hearon Jr, Denis J. Wakeham
International Journal of Exercise Science: Conference Proceedings
Mean arterial pressure (MAP) is either measured with an oscillometric cuff and then systolic (SBP) and diastolic (DBP) blood pressures are estimated from an unknown algorithm; or SBP and DBP are measured via auscultation and MAP calculated using measures of systolic pressure (SBP), diastolic pressure (DBP), and a form-factor (FF; equation: [(SBP-DBP)*FF]+DBP). The typical FF used is 0.33 though others (0.4) have been proposed. Recent work indicates that estimation of aortic MAP via a FF leads to inaccurate values and should therefore be interpreted with caution, whether this is the case for local MAP is unknown. While the implications for …
Effects Of Acute Grape Seed Extract Supplementation On Muscle Metaboreflex In Healthy Young Individuals, Alvin Apilado, William Boyer, Trevor Gillum, Sean Sullivan, Andrew Harveson, Albert Lira, Jong-Kyung Kim
Effects Of Acute Grape Seed Extract Supplementation On Muscle Metaboreflex In Healthy Young Individuals, Alvin Apilado, William Boyer, Trevor Gillum, Sean Sullivan, Andrew Harveson, Albert Lira, Jong-Kyung Kim
International Journal of Exercise Science: Conference Proceedings
Studies demonstrated that grape seed extract (GSE) increases the production of nitric oxide (NO) and reduces central sympathetic output. However, limited data have reported regarding the potential beneficial effects of this extract on blood pressure (BP) to increased sympathetic activity induced by the muscle metaboreflex (MMR) activation. Purpose: the aim of this study was to determine whether GSE supplementation could reduce the BP in response to static exercise and post exercise muscular ischemia (PEMI) in normotensive young adults. Methods: in 12 healthy subjects (7 male and 5 female, 24.6±3.4 yr), we compared acute effect of both GSE (600 mg) and …
Hemodynamic And Pressor Responses To Combination Of Yoga And Blood Flow Restriction, Savannah V. Wooten, Sten Stray-Gundersen, Hirofumi Tanaka
Hemodynamic And Pressor Responses To Combination Of Yoga And Blood Flow Restriction, Savannah V. Wooten, Sten Stray-Gundersen, Hirofumi Tanaka
International Journal of Exercise Science: Conference Proceedings
Blood flow restriction (BFR) training has been increasingly incorporated into a more common activity of daily exercise (e.g., yoga). However, BFR may increase blood pressure and myocardial oxygen demand by augmenting vascular resistance. Yoga is characterized by systemic isometric exercises and accompanied by marked pressor responses. This raises the concern of exaggerated cardiovascular responses when yoga is performed with BFR. Purpose: To determine the impact of a combination of yoga and BFR on cardiovascular responses. Methods: Twenty young healthy participants (M =10, F=10) performed 20 yoga poses with and without BFR bands placed on both legs. Beat by beat blood …
Comparison Of Acute Cardiometabolic Responses In A 7-Minute Body Weight Circuit To A 7-Minute Hiit Cycle Protocol, Cruz Armas, Robert J. Kowalsky Jr, Christopher M. Hearon
Comparison Of Acute Cardiometabolic Responses In A 7-Minute Body Weight Circuit To A 7-Minute Hiit Cycle Protocol, Cruz Armas, Robert J. Kowalsky Jr, Christopher M. Hearon
International Journal of Exercise Science: Conference Proceedings
Many smartphone applications available promote exercise engagement, specifically in short bouts of time. One such application “The 7-minute workout challenge” promotes a brief exercise bout, however details on the potential cardiometabolic health benefit is lacking. Purpose:To investigate the acute cardiometabolic responses of a 7-minute body-weight resistance exercise circuit (HICE) compared to a 7-minute high intensity interval training cycle protocol (HIIE). Methods: Apparently healthy and active young adults (N=12, 50% Female, 24.0±3.4 yr, BMI: 28.1±6.4 kg/m2) were enrolled in a randomized crossover study (HICE vs HIIE). The 12 HICE exercises were 30 seconds each using a standardized cadence, …