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Three Essays In Applied Econometrics, Collin Dean Hodges Jan 2019

Three Essays In Applied Econometrics, Collin Dean Hodges

Graduate Theses, Dissertations, and Problem Reports

The body of work presented here consists of a collection of research projects developed during my time as a graduate student at West Virginia University. As will soon become apparent, this collection of research topics is quite eclectic. This is, in part, due to the to the nature of the research process itself--where one often begins by asking one question and ends by answering a completely different one--but also due to the fact that my time at West Virginia University has provided me the opportunity to gain insight into a wide variety of economic fields as well as work on …


Quantifying Human Biological Age: A Machine Learning Approach, Syed Ashiqur Rahman Jan 2019

Quantifying Human Biological Age: A Machine Learning Approach, Syed Ashiqur Rahman

Graduate Theses, Dissertations, and Problem Reports

Quantifying human biological age is an important and difficult challenge. Different biomarkers and numerous approaches have been studied for biological age prediction, each with its advantages and limitations. In this work, we first introduce a new anthropometric measure (called Surface-based Body Shape Index, SBSI) that accounts for both body shape and body size, and evaluate its performance as a predictor of all-cause mortality. We analyzed data from the National Health and Human Nutrition Examination Survey (NHANES). Based on the analysis, we introduce a new body shape index constructed from four important anthropometric determinants of body shape and body size: body …


The Effects Of Obesity, Chronic Stress, And Exercise On Pancreatic Health, Abigail Tice Jan 2019

The Effects Of Obesity, Chronic Stress, And Exercise On Pancreatic Health, Abigail Tice

Graduate Theses, Dissertations, and Problem Reports

Obesity is concomitant with hyperglycemic conditions, increased proinflammatory cytokines, and increased oxidative stress. Under hyperglycemia, thioredoxin interacting protein (TXNIP) is increased and causes increased oxidative stress and pancreatic b-cell apoptosis. Chronic stress is associated with increased glucocorticoid levels and a proinflammatory environment. The purpose of this study was to examine the effects of obesity, chronic stress, and exercise on pancreatic health.

Lean Zucker Rats (LZRs) and Obese Zucker Rats (OZRs) were randomly assigned to four groups: 1) sedentary controls (C: n=8 per); 2) unpredictable chronic mild stress (UCMS) (S: n=8); 3) exercise (E: n=8); and 4) combined UCMS and exercise …