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Evaluating The Cost-Effectiveness Of St. John's Wort Versus Fluoxetine For The Treatment Of Mild To Moderate Depression, Lee Ann Thayer
Evaluating The Cost-Effectiveness Of St. John's Wort Versus Fluoxetine For The Treatment Of Mild To Moderate Depression, Lee Ann Thayer
Graduate Theses, Dissertations, and Problem Reports
The objective of this study was to determine the cost-effectiveness of St. John's Wort compared to fluoxetine from a third party perspective for the treatment of mild to moderate depression. Fluoxetine 20 mg daily was compared to St. John's Wort 300 mg thrice daily in a decision tree modeling depression management in the outpatient setting. Probabilities were obtained from a Medline search as well as input from an expert panel. Direct medical costs were obtained from medical offices in the Connecticut area with drug and herb cost based on 2002 published data. Several sensitivity analyses were performed. The cost-effectiveness ratio …