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Whispering Gallery Mode Microresonators For Lasing And Single Nanoparticle Detection, Lina He
Whispering Gallery Mode Microresonators For Lasing And Single Nanoparticle Detection, Lina He
All Theses and Dissertations (ETDs)
Whispering gallery mode: WGM) microresonators have attracted great interests due to the significantly enhanced light-matter interactions originating from their high quality factors and small mode volumes. They are suitable for a wide range of applications including sensing, lasing, nonlinear optics, and so forth. However, temperature fluctuations as one of the most common environmental noises disturb the cavity resonances and thus degrade the device stability and sensitivity. We introduce a wetting technique to coat the silica resonator with a thin layer of polymer which has the negative thermo-optic coefficient to compensate for the thermal effect in silica, and demonstrate complete thermal …
Fast Neuronal Imaging Using Objective Coupled Planar Illumination Microscopy, Diwakar Turaga
Fast Neuronal Imaging Using Objective Coupled Planar Illumination Microscopy, Diwakar Turaga
All Theses and Dissertations (ETDs)
Complex computations performed by the brain are produced by activities of neuronal populations. There is a large diversity in the functions of each individual neuron, and neuronal activities occur in the time scale of milliseconds. In order to gain a fundamental understanding of the neuronal populations, one has to measure activity of each neuron at high temporal resolution, while investigating enough neurons to encapsulate the neuronal diversity. Traditional neurotechniques such as electrophysiology and optical imaging are constrained by the number of neurons whose activities can be simultaneously measured or the speed of measuring such activities. We have developed a novel …
Developing High-Density Diffuse Optical Tomography For Neuroimaging, Brian White
Developing High-Density Diffuse Optical Tomography For Neuroimaging, Brian White
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Clinicians who care for brain-injured patients and premature infants desire a bedside monitor of brain function. A decade ago, there was hope that optical imaging would be able to fill this role, as it combined fMRI's ability to construct cortical maps with EEG's portable, cap-based systems. However, early optical systems had poor imaging performance, and the momentum for the technique slowed. In our lab, we develop diffuse optical tomography: DOT), which is a more advanced method of performing optical imaging. My research has been to pioneer the in vivo use of DOT for advanced neuroimaging by: 1) quantifying the advantages …