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Ranging Behavior, Group Cohesiveness, And Patch Use In Northern Bearded Sakis (Chiropotes Sagulatus) In Guyana, Christopher Shaffer
Ranging Behavior, Group Cohesiveness, And Patch Use In Northern Bearded Sakis (Chiropotes Sagulatus) In Guyana, Christopher Shaffer
All Theses and Dissertations (ETDs)
I conducted a 15 month study of the activity patterns, diet, ranging behavior, and group cohesiveness of northern bearded sakis: Chiropotes sagulatus) in a continuous lowland rainforest in southern Guyana. My study combined observational data with a novel GIS-based method for assessing food patch quality to assess how bearded sakis adjusted their ranging and grouping patterns in response to changes in resource quality. My study group consisted of at least 65 animals, making it the largest group of Chiropotes yet reported. Bearded sakis were highly active, spending most of their time traveling: 40% of activity) and feeding: 35% of activity). …
Allosteric Modulation Of Metabotropic Glutamate Receptor 5 As A Treatment For Pain, Michael Montana
Allosteric Modulation Of Metabotropic Glutamate Receptor 5 As A Treatment For Pain, Michael Montana
All Theses and Dissertations (ETDs)
Metabotropic glutamate receptor 5: mGlu5) has been suggested to play a role in the development and maintenance of chronic pain. mGlu5 is expressed at synapses throughout the pain neuraxis where it is believed to modulate the function of ion channels that underlie nociceptive transduction and transmission. Injections of mGlu5 agonists cause hypersensitivity or nocifensive behavior when administered peripherally, intrathecally, and centrally. In addition, pharmacological antagonism of mGlu5 has been suggested to be analgesic in a variety of animal pain models. Unfortunately, the selectivity of antagonists used in these studies has been called into question, suggesting that at least some of …