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Symptoms Of Major Depression: Their Stability, Familiality, And Prediction By Genetic, Temperamental, And Childhood Environmental Risk Factors, Kenneth S. Kendler, Steven H. Aggen
Symptoms Of Major Depression: Their Stability, Familiality, And Prediction By Genetic, Temperamental, And Childhood Environmental Risk Factors, Kenneth S. Kendler, Steven H. Aggen
Psychiatry Publications
Background: Psychiatry has long sought to develop biological diagnostic subtypes based on symptomatic differences. This effort assumes that symptoms reflect, with good fidelity, underlying etiological processes. We address this question for major depression (MD).
Methods: We examine, in twins from a population-based registry, similarity in symptom endorsement in individuals meeting criteria for last-year MD at separate interview waves and in concordant twin pairs. Among individuals with MD, we explore the impact of genetic-temperamental and child adversity risk factors on individual reported symptoms. Aggregated criteria do not separate insomnia from hypersomnia, weight gain from loss, etc. while disaggregated criteria do.
Results: …
"Our Captain Is A Gentleman”: Officer Elections Among Virginia Confederates, 1861-1862, Ryan C. O'Hallahan
"Our Captain Is A Gentleman”: Officer Elections Among Virginia Confederates, 1861-1862, Ryan C. O'Hallahan
Theses and Dissertations
Enlisted soldiers preferred to elect company- and regimental-level officers during the first year of the American Civil War. This thesis explores how early Confederate mobilization, class conflict between elites and non-elites, and Confederate military policies affected officer elections from spring 1861 to spring 1862 among Virginia Confederates. Chapter 1 explores how the chaotic nature of mobilization and common soldiers' initial expectations regarding their military service influenced elections from April 1861 until late July 1861. Chapter 2 details the changing nature of elections as elite officers faced challenges from non-elites and Confederate policies regarding furloughs and conscription forced officers to reconcile …
Integrating Genetics And Neuroimaging To Study Subtypes Of Binge Drinkers, Megan E. Cooke
Integrating Genetics And Neuroimaging To Study Subtypes Of Binge Drinkers, Megan E. Cooke
Theses and Dissertations
Risky alcohol use is a major health concern among college students, with 40.1% reporting binge drinking (5 or more drinks in one occasion) and 14.4% reporting heavy drinking (binge drinking on 5 or more occasions) in the past month. Risky alcohol use is thought to be the result of a complex interplay between genes, biological processes, and other phenotypic characteristics. Understanding this complex relationship is further complicated by known phenotypic heterogeneity in the development of alcohol use. Developmental studies have suggested two pathways to risky alcohol use, characterized by externalizing and internalizing characteristics, respectively. However, the underlying biological processes that …