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Behavioral And Quantitative Electroencephalogram Alterations During The Whisker Nuisance Task Following Mild Traumatic Brain Injury In Mice, David Wildman
Theses and Dissertations
Mild traumatic brain injury (mild TBI) has been shown to cause an array of symptoms in individuals lasting up to several years. Several publications have lead researchers to believe that parvalbumin axotomy and its associated changes with gamma oscillations may be the driving force for these symptoms. Several publications have demonstrated alterations in both resting gamma and evoked gamma by way of parvalbumin dysfunction. Our research analyzed resting and evoked gamma obtained by electroencephalograms (EEG) in nine mild TBI mice and six SHAM mice by utilizing a behavioral test known as the Whisker Nuisance Task (WNT). The central fluid percussion …
Evaluating The Clinical Utility Of A Novel Electroencephalography System For Assessing Perioperative Neurocognition In Older Surgical Patients, Lloyd H. Barnwell Iii
Evaluating The Clinical Utility Of A Novel Electroencephalography System For Assessing Perioperative Neurocognition In Older Surgical Patients, Lloyd H. Barnwell Iii
Theses and Dissertations
Postoperative delirium (POD) is a public health and research priority (American Society of Anesthesiologists, 2019). POD is a risk factor for long-term neurocognitive decline, and the rate of decline is directly proportional to the severity of POD (Vasunilashorn et al., 2018). Baseline cognitive function is a strong, independent predictor for POD (Culley et al., 2017). The International Perioperative Neurotoxicity Working Group recommends baseline cognitive function be assessed for older patients prior to surgery and anesthesia (Berger, et al., 2018). Perioperative cognitive screening tools trialed in anesthesia are not routinely incorporated into clinical practice related to validity, reliability, or practicality problems …