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Developmental Expression Of Monocarboxylate Transporter 1 And 4 In Rat Liver, Michael Ng, Justin Louie, Jieyun Cao, Melanie A. Felmlee
Developmental Expression Of Monocarboxylate Transporter 1 And 4 In Rat Liver, Michael Ng, Justin Louie, Jieyun Cao, Melanie A. Felmlee
School of Pharmacy Faculty Articles
PURPOSE: Monocarboxylate transporters (MCT) are proton-coupled integral membrane proteins that control the influx and efflux of endogenous monocarboxylates such as lactate, acetate and pyruvate. They also transport and mediate the clearance of drugs such as valproate and gamma-hydroxybutyrate. CD147 functions as ancillary protein that chaperones MCT1 and MCT4 to the cell membrane. There is limited data on the maturation of MCT and CD147 expression in tissues related to drug distribution and clearance. The objective of the present study was to quantify hepatic MCT1, MCT4, and CD147 mRNA, whole cell and membrane protein expression from birth to sexual maturity.
METHODS: Liver …
We (She, Me, Her) Are Not In Communication: An Autoethnography Of A Black College Administrator, Tanya Anderson
We (She, Me, Her) Are Not In Communication: An Autoethnography Of A Black College Administrator, Tanya Anderson
University of the Pacific Theses and Dissertations
I’m a first generation, previously low income, Christian, African American administrator at a California community college who struggled and felt alone throughout my journey. This autoethnography helped me make peace within my broken pieces. Within this dissertation, I highlight the impacts and hindrances within my education, family and career experiences. The purpose of this study is to offer the reader an insider view of how I ultimately became an administrator and with this information provide scholarship on how to more successfully integrate African American female leaders into higher education. The bonus chapter provides young women lessons learned along the way …