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Genetic Imaging Consortium For Addiction Medicine: From Neuroimaging To Genes, Scott Mackey, Kees-Jan Kan, Bader Chaarani, Nelly Alia-Klein, Albert Batalla, Samantha Brooks, Janna Cousijn, Alain Dagher, Michiel De Ruiter, Sylvane Desrivieres, Sarah W. Feldstein Ewing, Rita Goldstein, Anna Goudriaan, Mary M. Heitzeg, Kent Hutchison, Chiang-Shan R. Li, Edythe D. London, Valentina Lorenzetti, Maartje Luijten, Rocio Martin-Santos, Angelica M. Morales, Martin P. Paulus, Tomas Paus, Godfrey Pearlson, Renee Schluter, Reza Momenan, Lianne Schmaal, Gunter Schumann, Rajita Sinha, Zsuzsika Sjoerds, Dan J. Stein, Elliot A. Stein, Nadia Solowij, Susan Tapert, Anne Uhlmann, Dick Veltman, Ruth Van Holst, Hendrik Walter, Margaret J. Wright, Murat Yucel, Murat Yucel, Deborah Yurgelun-Todd, Derrek P. Hibar, Neda Jahanshad, Paul M. Thompson, David Glahn, Hugh Garavan, Patricia Conrod Jan 2016

Genetic Imaging Consortium For Addiction Medicine: From Neuroimaging To Genes, Scott Mackey, Kees-Jan Kan, Bader Chaarani, Nelly Alia-Klein, Albert Batalla, Samantha Brooks, Janna Cousijn, Alain Dagher, Michiel De Ruiter, Sylvane Desrivieres, Sarah W. Feldstein Ewing, Rita Goldstein, Anna Goudriaan, Mary M. Heitzeg, Kent Hutchison, Chiang-Shan R. Li, Edythe D. London, Valentina Lorenzetti, Maartje Luijten, Rocio Martin-Santos, Angelica M. Morales, Martin P. Paulus, Tomas Paus, Godfrey Pearlson, Renee Schluter, Reza Momenan, Lianne Schmaal, Gunter Schumann, Rajita Sinha, Zsuzsika Sjoerds, Dan J. Stein, Elliot A. Stein, Nadia Solowij, Susan Tapert, Anne Uhlmann, Dick Veltman, Ruth Van Holst, Hendrik Walter, Margaret J. Wright, Murat Yucel, Murat Yucel, Deborah Yurgelun-Todd, Derrek P. Hibar, Neda Jahanshad, Paul M. Thompson, David Glahn, Hugh Garavan, Patricia Conrod

Faculty of Social Sciences - Papers (Archive)

Since the sample size of a typical neuroimaging study lacks sufficient statistical power to explore unknown genomic associations with brain phenotypes, several international genetic imaging consortia have been organized in recent years to pool data across sites. The challenges and achievements of these consortia are considered here with the goal of leveraging these resources to study addiction. The authors of this review have joined together to form an Addiction working group within the framework of the ENIGMA project, a meta-analytic approach to multisite genetic imaging data. Collectively, the Addiction working group possesses neuroimaging and genomic data obtained from over 10,000 …


Clinical And Reliable Change In An Australian Residential Substance Use Program Using The Addiction Severity Index, Frank P. Deane, Peter J. Kelly, Trevor P. Crowe, Justin C. Coulson, Geoffrey C.B Lyons Jan 2013

Clinical And Reliable Change In An Australian Residential Substance Use Program Using The Addiction Severity Index, Frank P. Deane, Peter J. Kelly, Trevor P. Crowe, Justin C. Coulson, Geoffrey C.B Lyons

Faculty of Social Sciences - Papers (Archive)

Although the Addiction Severity Index (ASI) is one of the most frequently used measures in alcohol and other drug research, it has rarely been used to assess clinical and reliable change. This study assessed clients' clinical and reliable change at The Salvation Army residential substance abuse treatment centers in Australia. A total of 296 clients completed ASI interviews on admission to treatment and 3 months after discharge from treatment. Clients demonstrated significant improvement on all seven ASI composites. The range of reliable change for each ASI composite varied from 30% to 70%. More than two-thirds of clients experienced clinically significant …


A Theory Of Relative Deprivation And Myopic Addiction, Amnon Levy Aug 2006

A Theory Of Relative Deprivation And Myopic Addiction, Amnon Levy

Faculty of Business - Economics Working Papers

Myopic use of mind-altering substances is proposed to be equal to the product of the user’s current levels of relative-deprivation feeling and substance-tolerance. If initially this product is sufficiently large the user is trapped in a deprivation-use-addiction vicious cycle. There may be a relatively high addiction and socioeconomic position steady state and a relatively low one. If the users are initially located in the high steady state, an increase in treatment is clearly socially desirable. In contrast, the possible improvement of users’ socioeconomic position from increasing law-enforcement or socioeconomic opportunities might be dominated by a rise in users’ addiction level.