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Context And Target Search Reversal: Implicit Flexibility And Rapid Adaptation Of Relational Memories Using Visual Search, Ryan Hanson Dec 2013

Context And Target Search Reversal: Implicit Flexibility And Rapid Adaptation Of Relational Memories Using Visual Search, Ryan Hanson

Theses and Dissertations

Repeated perceptual exposure leads to increased accuracy and decreased response latency - referred to as perceptual facilitation or priming - and generally occurs in the absence of conscious memory experience. One example of a priming task which depends upon contextual relations is termed contextual cuing. It has long been held that context-dependent relations can only be acquired with deliberative or explicit processes. While context learning has historically been attributed to declarative memory, the existence of implicit context learning tasks may be better explained as an implicit relational learning process. Although implicit memories have long been characterized as relatively rigid, such …


Perdurance And Personhood: A Reply To Burge, Joel Knowles Dec 2013

Perdurance And Personhood: A Reply To Burge, Joel Knowles

Theses and Dissertations

This essay is a response to the attack on reductionist and perdurantist views of persons which Tyler Burge presents in a paper entitled "Memory and Perons". Burge's arguments appeal to a specific form of egocentric indexing called de se form, which he suggests is involved in the individuation conditions of the mental states entailed in the exercise of the core psychological competencies of personhood (i.e. intentional agency, perception with use, inference). Burge argues that the preservation of states with de se form requires the possession of a veridical de se memory competency, which in turn requires transtemporal agent identity. Burge …


The Role Of A Camkii/Pka-Protein Degradation-Glur2 Pathway In The Control Of Memory Updating Following Retrieval, Timothy Jarome Aug 2013

The Role Of A Camkii/Pka-Protein Degradation-Glur2 Pathway In The Control Of Memory Updating Following Retrieval, Timothy Jarome

Theses and Dissertations

Reconsolidation is thought to be a process whereby consolidated memories can be modified following retrieval. However, very little is known about the molecular mechanisms that regulate this reconsolidation process. In the present series of experiments we tested if memories "destabilize" or become labile following retrieval through a specific signaling pathway. We found that retrieval of a contextual fear memory differentially increased proteasome activity in the amygdala and hippocampus and resulted in unique changes in AMPA receptor subunit expression in these brain regions. These changes were dependent on CaMKII activity, which was required for increases in Rpt6-S120 phosphorylation, proteasome activity and …