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University of Windsor

Electronic Theses and Dissertations

2019

Breast Cancer

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A Translational Zebrafish Model To Study Breast Cancer Inflammation And Metastasis, Janice Tubman Dec 2019

A Translational Zebrafish Model To Study Breast Cancer Inflammation And Metastasis, Janice Tubman

Electronic Theses and Dissertations

Though modern medicine has greatly improved detection and treatment of breast cancer and overall survival rates are around 85%, this disease is still the second most fatal cancer in Canada. Once the cancer becomes metastatic, it is considered incurable and treatment strategies are directed towards maintenance of the disease rather than curing it. Another hurdle to breast cancer treatment is the severity of side effects from chemotherapeutics, for example cardiotoxicity and hepatotoxicity, that are sometimes fatal. Dexamethasone (Dex) is a synthetic glucocorticoid (GC) that has been shown to be effective at reducing the less severe side effects of chemotherapeutics, such …


Big Data Analytics For Complex Systems, Ashraf Mohamed Abou Tabl Sep 2019

Big Data Analytics For Complex Systems, Ashraf Mohamed Abou Tabl

Electronic Theses and Dissertations

The evolution of technology in all fields led to the generation of vast amounts of data by modern systems. Using data to extract information, make predictions, and make decisions is the current trend in artificial intelligence. The advancement of big data analytics tools made accessing and storing data easier and faster than ever, and machine learning algorithms help to identify patterns in and extract information from data. The current tools and machines in health, computer technologies, and manufacturing can generate massive raw data about their products or samples. The author of this work proposes a modern integrative system that can …