Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Entire DC Network
Compressive Sensing And Radar Imaging, John Montalbo
Compressive Sensing And Radar Imaging, John Montalbo
Theses and Dissertations
The field of remote sensing contains many unique and practical problems. Radar imaging, in all of its many forms, lies within this field of study. One problem is the need to acquire high-resolution images and store them on-board the system acquisition vessel . For some systems this could mean storing very high amounts of data, depending on the scene in question [3]. So a very natural goal is to store only what is absolutely necessary and nothing more. We investigate methods to compress signals into their most important components so that other parties can recover the original data completely or …
Development Of Arginyl-Trna Synthetase From Pseudomonas Aeruginosa As A Platform To Screen For Inhibitors Of Protein Synthesis, Daniel Cantu
Development Of Arginyl-Trna Synthetase From Pseudomonas Aeruginosa As A Platform To Screen For Inhibitors Of Protein Synthesis, Daniel Cantu
Theses and Dissertations
Pseudomonas aeruginosa is a Gram- negative bacteria that is the leading cause of mortality in immunocompromised patients. Arginyl-tRNA synthetase (ArgRS) is an enzyme that catalyzes the covalent attachment of arginine to the cognate tRNAArg during protein synthesis. Scintillation proximity assays (SPA) were adapted to the aminoacylation assay and used to screen, one natural compound library (800) and one synthetic compound library (890) to identify inhibitors of the activity of ArgRS. Five compounds were identified which inhibited greater than 50% of enzymatic activity, two of these compounds (BT04F10 and BT11F03) exhibited promising MICs against Gram+ bacteria and moderate activity against Gram- …