Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network

Open Access. Powered by Scholars. Published by Universities.®

University of Tennessee, Knoxville

2005

Canine

Articles 1 - 2 of 2

Full-Text Articles in Entire DC Network

Correlation Of Age And Incidence Of Pancreatic Exocrine Nodular Hyperplasia In The Dog, Shelley Newman, J M. Steiner, K Woosley, L Barton Jan 2005

Correlation Of Age And Incidence Of Pancreatic Exocrine Nodular Hyperplasia In The Dog, Shelley Newman, J M. Steiner, K Woosley, L Barton

Faculty Publications and Other Works -- Biomedical and Diagnostic Sciences

The purpose of this study was to determine the prevalence of pancreatic nodular hyperplasia (NH) and its relation to age in the dog. A total of 101 dogs were enrolled. The pancreas was evaluated by histology and hyperplastic lesions were detected and scored. Age was recorded from the medical records. Correlation of age with inflammation and presence of hyperplastic lesions was evaluated. Of the 101 dogs, 81 (80.2%) had evidence of NH. Twenty-five of the 101 dogs did not have evidence of pancreatic inflammation, necrosis, and/or fibrosis, 17 (68.0%) of which had evidence of NH. Mean +/- SD age in …


Canine Hepatic Neuroendocrine Carcinoma: An Immunohistochemical And Electron Microscopic Study, A K. Patnaik, Shelley Newman, T Scase, R A. Erlandson Jan 2005

Canine Hepatic Neuroendocrine Carcinoma: An Immunohistochemical And Electron Microscopic Study, A K. Patnaik, Shelley Newman, T Scase, R A. Erlandson

Faculty Publications and Other Works -- Biomedical and Diagnostic Sciences

Ten dogs with neuroendocrine carcinoma of the liver were selected for inclusion in the study. Clinical signs were anorexia (7), vomiting (5), polydipsia/polyuria (3), icterus (2), lethargy (2), weight loss (2), paresis (1), ataxia (1), weakness (1), collapse (1), and urinary tract infection (1). Hematologic and biochemical abnormalities included anemia (2/8), leukocytosis (4/8), high liver enzyme activity (serum alkaline phosphatase, 7/9; alanine transaminase, 7/9; aspartate transaminase, 8/9), and high total bilirubin (6/9). Grossly, the tumors were diffuse, involving all liver lobes in six dogs, and two dogs had various-sized nodules in addition to diffuse involvement. Histologically, there were eight tumors …