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Instrumentation For, And Application Of, Novel Electrochemical Tools For In Vivo Analysis Of Neurotransmitters In The Context Of Psychiatric Disease, Rhiannon Robke Jan 2018

Instrumentation For, And Application Of, Novel Electrochemical Tools For In Vivo Analysis Of Neurotransmitters In The Context Of Psychiatric Disease, Rhiannon Robke

Theses and Dissertations

ABSTRACTSerotonin’s involvement in many physiological processes including anxiety, stress, compulsivity, and mood has been speculated for decades. Insufficient progress in our understanding of serotonin chemistry is due to the lack of effective tools to selectively measure this neurotransmitter on a neurotransmission-relevant time scale in vivo. An analytical technique for serotonin measurements, fast-scan cyclic voltammetry (FSCV), was pioneered in the last decade in anesthetized rodents and is beginning to shed light on the complexity of serotonergic activity on a sub-second timescale. Complementary, more recent technological innovations have enabled ambient neurotransmitter levels to be determined every few seconds using a method called …


Analysis Of Pellet-Cladding Mechanical Interaction On U3si2 Fuel With A Multi-Layer Sic Cladding Using Bison, Ray A. Freeman Jan 2018

Analysis Of Pellet-Cladding Mechanical Interaction On U3si2 Fuel With A Multi-Layer Sic Cladding Using Bison, Ray A. Freeman

Theses and Dissertations

U3Si2 is currently being considered as a possible replacement for the current light water reactor fuel, UO2. U3Si2’s high melting temperature, high uranium density, and high thermal conductivity are favorable in accident conditions, such as a loss of coolant accident. Improved accident performance is further expected when paired with a SiC/SiC cladding, since it provides relatively high strength and a high oxidation resistance.

Modeling of U3Si2 and SiC/SiC in reactor is currently very important since much of their behavior is still unknown. By implementing models that describe the properties of U3Si2 and SiC/SiC into INL’s fuel performance code BISON, performance …


Analysis Of Evacuation Behaviors And Departure Timing For October 2016’S Hurricane Matthew, Erika O. Pham Jan 2018

Analysis Of Evacuation Behaviors And Departure Timing For October 2016’S Hurricane Matthew, Erika O. Pham

Theses and Dissertations

During a hurricane, an individual’s risk perception does not remain static. Spatial and temporal variations of a hurricane will shift perceptions of risk, and complicating this dynamic are information-seeking processes increasingly reliant on the individual’s self-motivated interpretation of information sources. Initial evacuation resistance or willingness could change even after evacuations are ordered, affecting evacuation preferences and departure times. Because Hurricane Matthew’s continually shifting track had virtually nonstop coverage, evacuation decisions were also being modified as residents either grew more or less certain of their safety.

This research investigates the evacuation behaviors associated with Hurricane Matthew in October of 2016. It …