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Choline Supplementation And Dna Methylation In The Hippocampus And Prefrontal Cortex Of Rats Exposed To Alcohol During Development, Nicha K. H. Otero
Choline Supplementation And Dna Methylation In The Hippocampus And Prefrontal Cortex Of Rats Exposed To Alcohol During Development, Nicha K. H. Otero
Theses and Dissertations
Fetal Alcohol Spectrum Disorders (FASD) refers to the effects of alcohol exposure during development on individuals. Some of the most frequent deficits seen in children with FASD and in animal models of FASD are spatial memory impairments and impaired executive functioning, which are likely related to alcohol-induced alterations of the hippocampus and medial prefrontal cortex (mPFC), respectively. Choline, a nutrient supplement, has been shown in a rat model to ameliorate some of alcohol‟s teratogenic effects and this effect may be mediated through choline‟ effects on DNA methylation. This study used a rat model of FASD to investigate the underlying mechanisms …
The Interaction Between Caffeine Consumption, Alcohol Use, And Amount Of Sleep On Bone Health, Haley Davis-Martin
The Interaction Between Caffeine Consumption, Alcohol Use, And Amount Of Sleep On Bone Health, Haley Davis-Martin
Theses and Dissertations
Using cross-sectional data from the 2009-2010 and 2013-2014 NHANES surveys we examined potential interaction between caffeine consumption, alcohol use, and sleep and its relation to bone health, measured using bone mineral density (BMD). The study population consisted of 2,405 individuals at least 40 years old who were not taking any medications or hormones that would affect bone mineral density. Several factors such as smoking status, exercise, dietary intake of calcium, dietary intake of vitamin D, dietary intake of phosphorus, presence of arthritis, age, gender and race were considered in this project. We found a statistically significant negative linear relationships between …