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University of Richmond

Theses/Dissertations

1967

Mice

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A Comparative Study Of The Sulfhydryl Groups In The Gastrocnemius Of The Normal And X-Irradiated Pet Mouse, Robert Edward Shervette Aug 1967

A Comparative Study Of The Sulfhydryl Groups In The Gastrocnemius Of The Normal And X-Irradiated Pet Mouse, Robert Edward Shervette

Master's Theses

It has been recognized that hyperpigmentation of the skin is the result of eliminating the. -SH inhibition when treatment is by x-irraidiation. The results of a. study by fieams and Schaeffer indicate : a progressive increase of melanocytes in the skin with an increasing dosage of x-irradiation. However, it was also noted that the effect of x-irradiatin on the gastrocnemius of the PET mouse resulted in a decrease in the number of intramuscular melanocytes. The present study was designed to determine whether the changes in the x-irradiated muscle is related to possible changes in -SH concentration.The technique employed is a …


The Effects Of A Nerve Growth-Promoting Protein On The Integument Of Pet Mice, Craig Bauman Satterlee Jun 1967

The Effects Of A Nerve Growth-Promoting Protein On The Integument Of Pet Mice, Craig Bauman Satterlee

Master's Theses

A factor which specifically stimulates the growth of sensory and sympathetic nerve cells has been under investigation for a number of years. This factor, originally isolated in 1951, from mouse sarcomas 37 and 180, was named the "nerve growth factor". Its action was first shown in vivo by inoculating the sarcoma into chick embryos and subsequently in vitro by culturing chick ganglia and mouse sarcoma together. In the years immediately following the initial discovery, much more potent sources of NGF were found in the salivary glands and salivary secretions of a variety of species. These include rattle snake venom, and …