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Alterations In Calcium Homeostasis And The Insulin-Like Growth Factor Signaling Pathway Induced By Carcinogenic Polycyclic And Halogenated Aromatic Hydrocarbons In Human Mammary Epithelial Cells, Stacey L. Tannheimer

Pharmaceutical Sciences ETDs

Breast cancer is a major health concern for women, with only a small percent of the risk factors currently identified. It has been estimated that environmental factors may contribute to up to 80% of breast cancer cases. Many environmental carcinogens, such as polycyclic and halogenated aromatic hydrocarbons (PAHs and HAHs), are proven mammary carcinogens in animal models. Therefore, these studies were conducted to elucidate potential roles of PAHs and HAHs in alterations in known signaling pathways in human mammary epithelial cells (HMEC). Carcinogenic PAHs have previously been shown to produce sustained alterations in the calcium (Ca2') homeostasis of lymphocytes Therefore, …

The Slide: Image And Object, Cindy D. Abel Morris

Art & Art History ETDs

Through an extensive review of the literature of the history and methodology of art history and visual resources, this thesis charts the effect of the use of slides for the discipline of art history.

The three chapters examine the conjunction between slides and art history. Chapter one gives an account of the pedagogical and practical reasons for the current predominance of the slide as the reproduction of choice in art history, concluding with a discussion of the relative importance of the text and image for art history. The second chapter briefly traces the evolution of magic lantern to 35mm format …

Rethinking Martín Chambi, Michele M. Penhall

Art & Art History ETDs

This dissertation examines the photographs of Peruvian photographer Martín Chambi. A successful photographer and celebrated artist during much of his life, Chambi and his work was largely forgotten about since the 1950s and unknown outside of South America. During the 1970s he was rediscovered and his photographs made known to audiences around the world. As a result, new interpretations of him as an artist have emerged which are different from those during his life. The photographs he is known for today are not those he considered his artistic work.

Roots Of The New Mexico Women's Movement: Missionaries And The New Mexico Woman's Christian Temperance Union, Clare Denise O'Leary-Siemer

History ETDs

This thesis is an examination of the roots of the New Mexico women's movement and the unification of Protestant women's networks in New Mexico. Chapter 1 begins with the entry of Protestant evangelists and their wives prior to the Civil War. Chapter 2 looks at the Protestant missionaries who, after the Civil War, intensified their efforts to Americanize the West. Chapter 3 examines the early crusade of the new Mexico Woman's Christian Temperance Union (NMWCTU), 1883-1906.

Missionaries and lay women established an evangelical alliance which became the basis of a growing female reform movement in New Mexico. The NMWCTU was …

Surface Micromachined Pressure Sensors, William P. Eaton Iv

Electrical and Computer Engineering ETDs

Surface micromachined pressure sensors were designed, modeled, fabricated, and tested. They employed a piezoresistive transduction mechanism and were based upon circular diaphragms, which vary from 50 to 1000 μm in diameter and 1 to 2 μm in thickness. The piezoresistors were placed in Wheatstone bridge configurations to provide simple signal amplification and first order temperature compensation.

Of the different micromachining techniques, surface-micromachining has the advantage of being the most similar to integrated circuit manufacturing. Hence an existing IC equipment set can be used to create mechanical structures. Furthermore, the monolithic integration of a mechanical device with control electronics is simpler …

The Poems And Prose Of Elizabeth Moody, Jan Wellington

English Language and Literature ETDs

My dissertation is a scholarly edition of the poems, reviews, and letters of Elizabeth Moody (1737-1814), an English writer whose work has been out of print for nearly two centuries and has never been collected. Comprised of 109 poems, 29 reviews, and six letters, the edition contains substantial new biographical information and many heretofore undiscovered texts.

The product of a privileged, upper-middle-class milieu and a locale famed for wit and art, Moody from an early age conceived of herself as a reader, writer, and critic. In the edition's biographical/critical introduction I examine how her identity and writing were shaped by …

Giving Birth To Onions, Stefanie London Feld-Galbraith

Art & Art History ETDs

I have always questioned the authority of Art History. I was taught that the historians gave a true, unbiased examination of art, while the critics and the artists created works wrought with subjectivity. But experience has taught me that nothing can be looked upon objectively. Even as we look, we are changing what we see.

There is not just one truth, one voice; there are many, and this is mine. The stories you are about to see are real, except for the ones I made up, which are also real. I think the truth must be something that wraps around …

Hydrologic Budget Analysis And Numerical Simulations Of Groundwater Flow In Los Alamos Canyon Near Los Alamos, New Mexico, Robert Norman Gray

Earth and Planetary Sciences ETDs

A hydrologic budget analysis for the Los Alamos Canyon watershed was prepared including annual budgets for the 1993, 1994, and 1995 water years and detailed budget calculations for the upper basin and middle/upper canyon areas covering nine separate stress periods from 7/10/94 to 11/2/95 corresponding to varying alluvial aquifer behaviors. Data sources included daily measurements of precipitation and snowpack depths, streamflow discharge, and latent heat energy flux from which evapotranspiration rates were determined. Average annual precipitation rates over the watershed varied from ~23 to ~31 inches during the analyzed periods. The annual evapotranspiration component was determined to represent between ~ …

The Terraces Of Cochiti Canyon: Soil Development And Relation To Tectonism In The Pajarito Fault Zone, Scott Benjamin Aby

Earth and Planetary Sciences ETDs

The history of motion on splays of the Pajarito Fault Zone in the area of Cochiti Canyon in the Jemez Mountains is examined using morphometric techniques and investigations of river terrace soils and deformation. Hypsometry, sinuosity and long-profile analysis all suggest that the main splay of the Pajarito Fault has been active in the late Pleistocene and possibly Holocene, but no calibration is available that numerically constrains this activity. Terraces were mapped and correlated based on soil development and landscape position, Correlation revealed the presence of three strath terraces between 87 and 18 .5 meters above present grade and one …

Alterations In Human B Cell Calcium Homeostasis By Polycyclic Aromatic Hydrocarbons: Possible Associations With Cytochrome P450 Metabolism And Increased Tyrosine Phosphorylation, Barbara J. Mounho

Pharmaceutical Sciences ETDs

Polycyclic aromatic hydrocarbons (PAHs), are known immunotoxicants in animals, and are suspect toxins to the human immune system. The mechanism(s), however, by which PAHs exert immunosuppression have not been fully elucidated. Previous studies conducted in our laboratory have shown that PAHs, such as 7,12-dimethylbenz(a)- anthracene (DMB A) and benzo(a)pyrene (BaP) may exert their immunotoxic effects by altering intracellular calcium (Ca2+) homeostasis in lymphocytes. Intracellular Ca2+ is an important second messenger in the immune response, and the mobilization of Ca2+ is critical in the transduction of intracellular signals from the plasma membrane to the nucleus. The overall objective of this project …