Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Entire DC Network
The Taxonomic And Systematic Relationships Of Several Salt Marsh Fucus Taxa (Heterokontophyta, Phaeophyceae) Within The Gulf Of Maine And Ireland Examined Using Microsatellite Markers, Aaron L. Wallace
Doctoral Dissertations
The present thesis utilizes microsatellite markers to examine genetic affinities between several salt marsh Fucus ecads in order to ascertain their relationships with attached parental species. Chapter I provides an introduction to the genus Fucus and discusses morphological plasticity, systematic difficulties, and studies of hybridization between different Fucus species.
Chapter II describes my development of microsatellite markers for Fucus. Four polymorphic microsatellite loci were used to determine the origin of a dwarf muscoides-like Fucus from the Brave Boat Harbor (ME) salt marsh. Similar forms were originally described in Europe, and appear to be derived from F. vesiculosus L. However, my …
Function, Expression And Evolution Of The *Src Family Kinases In Caenorhabditis Elegans, Chery Angel Whipple
Function, Expression And Evolution Of The *Src Family Kinases In Caenorhabditis Elegans, Chery Angel Whipple
Doctoral Dissertations
The vertebrate proto-oncogene, Src, is the prototype of a family of membrane-associated protein tyrosine kinases involved in cell signaling pathways that control cell growth, development, and differentiation. Activation of Src by mutation or overexpression has been implicated in a range of cancers, particularly breast and colon cancer. Inappropriate activation of Src has pronounced oncogenic effects on cell morphology, adhesion, and motility. Despite its implications in cancer, the normal biological role of Src is not well understood.
I used the nematode C. elegans to investigate the expression, function, and evolution of two src genes (src-1 and src-2) utilizing a combination of …