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University of New Hampshire

Theses/Dissertations

2001

Chemistry

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Identification Of Suppressors Of Spt10 That Affect Adh2 Expression In The Yeast Saccharomyces Cerevisiae, Bradley David Anderson Jan 2001

Identification Of Suppressors Of Spt10 That Affect Adh2 Expression In The Yeast Saccharomyces Cerevisiae, Bradley David Anderson

Doctoral Dissertations

Suppression of the effects of an spt10 mutation on ADH2 expression is a phenotype shared by a small number of genes involved in the regulation of gene expression. All six known suppressors of spt10 are either components of the CCR4-NOT Complex (CCR4, CAF1, NOT4), or have been shown to interact with the complex ( DBF2, SRB9, SRB10). This indicated that spt10 suppression may be characteristic of CCR4-like gene regulation. In this work, I conducted a screen for additional suppressors of spt10 at ADH2. The screen identified no less than ten complementation groups, including ADH2 and two known suppressors of spt10, …


Remote Optical Fiber Sensing Based On Reflectance Due To The Swelling Of Polymer Particles Produced By Dispersion Polymerization, Siobhan P. Milde Jan 2001

Remote Optical Fiber Sensing Based On Reflectance Due To The Swelling Of Polymer Particles Produced By Dispersion Polymerization, Siobhan P. Milde

Doctoral Dissertations

Poly (4-vinyl pyridine) particles produced by dispersion polymerization were suspended in a hydrogel membrane and used for remote measurements employing fiber optic sensors. The refractive index of poly(4-vinyl pyridine) particles is higher than the refractive index of the hydrogel. At low pH, protonation of the poly(vinyl pyridine) causes the particles to swell reducing their refractive index and lowering membrane turbidity. The membrane response to pH was monitored using instrumentation originally that was constructed by Michael Civiello and was further developed in this work. A new hydrogel, HYPAN, was evaluated as the medium in which the particles are suspended. Methods for …