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Possible Association Between Response Inhibition And A Variant In The Brain-Expressed Tryptophan Hydroxylase-2 Gene, Scott F. Stoltenberg, Jennifer M. Glass, Steven T. Chermack, Heather A. Flynn, Sheng Li, Margaret E. Weston, Margit Burmeister
Possible Association Between Response Inhibition And A Variant In The Brain-Expressed Tryptophan Hydroxylase-2 Gene, Scott F. Stoltenberg, Jennifer M. Glass, Steven T. Chermack, Heather A. Flynn, Sheng Li, Margaret E. Weston, Margit Burmeister
Department of Psychology: Faculty Publications
The ability to inhibit a response is an important component of normal behavioral control and is an aspect of psychopathology when diminished. Converging evidence implicates the serotonergic neurotransmitter system in response inhibition circuitry.
Objectives — The present study examined potential associations between serotonergic genetic markers and response inhibition as indexed by Stop Task performance.
Methods — College-age participants (N= 199) completed self-report questionnaires, the computerized Stop Task, and donated buccal cells for genetic analyses. Statistics were analyzed by ANOVA.
Results — Stop Signal reaction time was not associated with allelic variation at a monoamine oxidase A promoter length polymorphism or …