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Salient Beliefs And Social Influence On Intentions To Misuse Prescription Opioid Pain Relieving Drugs For Recreational Purposes: An Application Of The Theory Of Planned Behavior, Robert Eugene Davis
Salient Beliefs And Social Influence On Intentions To Misuse Prescription Opioid Pain Relieving Drugs For Recreational Purposes: An Application Of The Theory Of Planned Behavior, Robert Eugene Davis
Electronic Theses and Dissertations
Purpose: The purpose of the proposed study was to evaluate the utility of the Theory of Planned Behavior (TPB) in predicting intentions to use prescription opioid pain relieving drugs for recreational purposes among a sample of college students, while identifying salient beliefs that underlie recreational use in order to inform future intervention efforts among this population. Methodology: A cross-sectional electronic survey design was used to evaluate the direct measures of TPB constructs, salient beliefs, substance use, and individual characteristics of a random sample of university students. Results: Among our sample (N=776) more than 20% reported lifetime use of prescription opioids …
Molecular Characterization Of The Opioid Receptors: Design, Development, And Preclinical Evaluation Of Salvinorin A-Based Molecular Probes., Adam Keasling
Electronic Theses and Dissertations
The field of salvinorin chemistry represents a novel and emerging field of opioid research. The novelty is derived from the lead pharmacophore: salvinorin A — a neoclerodane diterpenoid natural product isolated from Salvia divinorum. Salvinorin A represents a pharmacologically unique compound in that it is the first known non-nitrogenous KOR subtype-selective agonist, exhibits a comparatively safe physiological profile with no reports of toxicological effects in clinical trials, and, most importantly, has a steadily growing body of literature indicating potentially useful clinical applications (e.g. antinociceptive, anti-addictive, antipruritic, neuroprotective, etc.). This has encouraged the development of analogues as essential molecular probes to …