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The Effects Of Rumination On Psychological And Biological Recovery From Stress In Depression, Joelle Lemoult
The Effects Of Rumination On Psychological And Biological Recovery From Stress In Depression, Joelle Lemoult
Open Access Dissertations
Diathesis-stress models of depression highlight that stress triggers the onset of a depressive episode. Increasing evidence, however, suggest that increased risk comes not from the initial response to stress, but rather from difficulty regulating emotions in a way that facilitates recovery. Rumination is a maladaptive emotion regulation strategy shown to prolong negative affect in response to distress. The current study extends past research by comparing the effects of a rumination versus distraction induction on biological and psychological recovery from stress among individuals with major depressive disorder (MDD) and healthy controls (CTLs). Participants were exposed to a psychosocial stressor and then …
Keeping The Balance: The Role Of The Serotonin Subtype 1a Receptor In Regulating Cortisol Secretion In The Gulf Toadfish (Opsanus Beta), Lea R. Medeiros
Keeping The Balance: The Role Of The Serotonin Subtype 1a Receptor In Regulating Cortisol Secretion In The Gulf Toadfish (Opsanus Beta), Lea R. Medeiros
Open Access Dissertations
It is well established that serotonin (5-HT; 5-hydroxytryptamine) plays a role in regulating the mammalian hypothalamic-pituitary-adrenal (HPA) axis via the 5-HT receptor subtype 1A (5-HT1A). To date, there has not been a comprehensive investigation of the molecular, pharmacological and physiological aspects of the 5-HT1A receptor and its role in the activation of the hypothalamic-pituitary-interrenal (HPI) axis in a single species of teleost fish. The Gulf toadfish (Opsanus beta) 5-HT1A receptor was cloned and sequenced, showing 67.5% amino acid similarity to the human homologue. The 5-HT1A receptor was distributed throughout the brain, with the midbrain/diencephalon region containing significantly higher transcript levels …