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Pediatric Providers’ Experiences Assessing Young Children’S Emotions And Behaviors, Vaibhavi Venkataramanan, Akira Isaac B.S., Sara Bufferd Ph.D.

The Cardinal Edge

Introduction: Preschool-aged children experience anxiety and mood-related emotions (e.g., irritability, fears) and behaviors (e.g., tantrums) that are developmentally normative, but can overlap with psychopathology, making assessment challenging (Bufferd et al.,2016). Most children see pediatric medical providers annually, and providers can evaluate them. However, providers face challenges like limited training and time (Bean et al.,2000;Heneghan et al.,2008). Accurate and early identification of emotional and behavioral difficulties is critical to support young children’s mental health and prevent worsening problems.

Methods: Participants included N=22 pediatricians who see 3-5-year-old children in their practice. Pediatricians completed an online survey about their experiences assessing young …

Neurotropic Manifestations As A Potential Risk Factor For Schizophrenia Following In Utero Exposure To Sars-Cov-2, Mir Ali R Talpur, Omar H. Elsayed, Rif S. El-Mallakh

The University of Louisville Journal of Respiratory Infections

Background: COVID-19 infection is associated with neurologic and psychiatric morbidity that suggests a direct effect of the virus or secondary effect of an inflammatory process. These neuropsychiatric consequences may increase the likelihood of schizophrenia in the offspring of women who become infected with COVID-19 during their pregnancy.

Methods: We performed a directed narrative review of the literature focusing on the proposed pathophysiological processes that lead to schizophrenia and known pathological consequences of COVID-19 infection.

Results: Schizophrenia in adult offspring has been associated with maternal infections during pregnancy by a wide range of respiratory and neurotropic pathogens. Spikes in the incidence …

Early Mathematical Abilities Of 48-Month-Old Children With Williams Syndrome., Jenna N. Tinnell

College of Arts & Sciences Senior Honors Theses

Williams syndrome (WS) is a genetic neurodevelopmental disorder associated with relative strengths in concrete vocabulary, nonverbal reasoning, and verbal short-term memory and considerable weaknesses in visuospatial construction and relational language. While the cognitive profile of WS has been studied extensively, there have been few studies of the early mathematical abilities of children with WS and the cognitive predictors of these abilities. The purpose of this study was to describe the early mathematical abilities of 48-month-olds with WS and determine the concurrent cognitive predictors of these abilities. The Differential Ability Scales–second edition (DAS-II) was used to determine cognitive and mathematical abilities …

Inner Ear Development And Advances In Inner Ear Organoid Formation, Paige Avery

The Cardinal Edge

The inner ear houses the cochlea which contains hair cells responsible for the transduction of sound waves. The process of forming these hair cells responsible for hearing is a complicated process consisting of many signaling factors that allow ectoderm to form into the otic placode, the otic vesicle, and finally prosensory cells such as hair cells (Schlosser, 2006). Loss of these hair cells contributes to deafness and hearing loss throughout life, and regeneration of these cells may serve as a therapeutic agent for those with irreversible damage. This review looks at the development of the otic placode and hair cells …

Violence And Development: The Cost Countries Pay For High Rates Of Homicide, Brittany Lowe

The Cardinal Edge

Violence is one of the largest and most persistent humanitarian crises across the globe. Understanding violence’s role in economic costs and losses is crucial to informing and guiding decision makers. This study uses international panel data to conduct a log-linear regression with time and country fixed effects. It focuses on studying the causal effects of violent crime on GDP at an aggregate, international level. The results find that the homicide rate has a statistically significant, negative effect on GDP per capita. Acts of violence come not just at a humanitarian cost, but also at the cost of economic progress and …

Early Communication Abilities Of 24-Month-Old Children With Williams Syndrome As Measured By The Communication Complexity Scale., Sean B. Woods

College of Arts & Sciences Senior Honors Theses

Williams syndrome (WS) is a neurodevelopmental disorder associated with intellectual disability accompanied by a distinct cognitive profile. Despite their socially outgoing nature, children with WS exhibit delayed communication development and specific deficits across various functions of communication. The purpose of this study was to describe the range of communication complexity observed in 24-month-olds with WS and determine relations between communication complexity and other areas of cognitive development. The communication complexity of 17 24-month-old children with WS was measured using the Communication Complexity Scale (CCS), which quantifies optimal and typical communication complexity, as well as optimal communication for Joint Attention (JA) …

Cost Countries Pay For High Homicide Rates, Brittany Lowe

Grawemeyer Colloquium Papers

This research finds the economic cost, in terms of GDP per capita, to countries for increased violence using typical econometric models, and then makes recommendations to decision makers about funding allocation of violence prevention programs based off its findings.

Sustainable Building, Spring/Summer 2009, Issue 20

Sustain Magazine

No abstract provided.

Urban Regeneration, Fall/Winter 2003, Issue 7

Sustain Magazine

No abstract provided.

The Migration And Developmental Remodeling Of Intrinsic Interneurons In Visual Thalamus And The Role Of Retinal Signaling., Naomi E. Charalambakis

Electronic Theses and Dissertations

The dorsal lateral geniculate nucleus (dLGN) of the mouse is a model system to study the development of thalamic circuitry. While most studies focus on relay neurons of dLGN, little is known about the factors regulating the development of the other principal cell type, intrinsic interneurons. To date, the targeting and migratory path of dLGN interneurons as well as their morphological development remains unclear. Here we examined whether the migration, structure, and function of interneurons relies on retinal signaling. We took a loss-of-function approach and crossed GAD67-GFP mice, which express green fluorescent protein (GFP) in dLGN interneurons, with math5 nulls …

The Roles Of Anxious Rearing, Negative Affect, And Effortful Control In A Model Of Risk For Child Perfectionism., Nicholas William Affrunti

Electronic Theses and Dissertations

Our understanding of perfectionism and its developmental trajectory and impact on children has experienced a recent growth. Research has shown that child perfectionism is associated with a number of negative outcomes including anxiety and depressive disorders, hopelessness, poor psychosocial treatment outcomes, and researchers have not found it to be associated with actual achievement. As such, research has begun to examine the developmental risk factors that predict for its development. The current study proposes utilizing a developmental psychopathology approach, one that purports a complex interaction among internal, external, risk and protective processes in the developmental of perfectionism. Specifically, the study examined …

Nowhere To Go : Informal Settlement Eradication In Kigali, Rwanda., Emily E Benken

College of Arts & Sciences Senior Honors Theses

Following the new world order of the post-Cold War era, the rise of developmentalism stressed the moral necessity of installing capitalist models of growth in the global south. The reproduction of narratives of modernity and teleological progression were reproduced in numerous African cities and actualized in policies related to urban development. The consequent trend of urbanization has been the systemic eradication of informal settlements and large-scale displacement to make way for modern, productive urban areas.

One site of this pattern is Kigali, Rwanda. Since the turn of the century, official “vision projects” released by the Rwandan government have reimagined the …

Trunk And Respiratory Motor Control In Typically Developing Children And Its Implications In Children With Chronic Spinal Cord Injury., Goutam Singh

Electronic Theses and Dissertations

Independent sitting is a major milestone and is also a prerequisite for optimal performance of activities of daily living (ADLs). Development of sitting posture control is a dynamic process involving control of degrees of freedom of head and trunk. Traditionally, trunk has been modeled as a single unit (segment). However, recent studies have suggested that it is made up multiple spinal units, controlled by a combination of trunk muscles. During typical development, posture control of trunk is different for different trunk segments. This motor development of trunk control is a complex process due to constant interaction between the nervous system …

The Role Of Neurotrophin Receptors In Taste Development., Da Fei

Electronic Theses and Dissertations

Brain-derived neurotrophic factor (BDNF) and neurotrophin-4 (NT-4) are two neurotrophins that play distinct roles in geniculate (taste) neuron survival, taste innervation and taste bud formation. These two neurotrophins activate the same receptors tyrosine kinase B (TrkB) and a pan-neurotrophin receptor (p75). While the roles of these neurotrophins have been well studied, it remains unclear how much BDNF and NT-4 function through TrkB and p75 to regulate taste development in vivo. In chapter 2, I compared taste development in TrkB-/- mice and Bdnf-/-/Ntf4-/- mice to determine if these deficits were similar. If so, this would indicate that the functions of both …

From Colonialism To Neoliberalism : Modernity And The State Production Of A Bedouin-Transjordanian National Identity., Amanda M. Yee

College of Arts & Sciences Senior Honors Theses

No abstract provided.

Depression As A Risk Factor For Breast Cancer : Investigating Methodological Limitations In The Literature., Patrick Pössel, Erica Adams, Jeffrey C. Valentine

Faculty Scholarship

Purpose: A relationship between depression and the development of breast cancer has not been convincingly shown in the research conducted over the past three decades. Methods: In an effort to better understand the conflicting results, a review was conducted focusing on the methodological problems associated with this literature, including time frame between the assessment of depression and the diagnosis of breast cancer and the use of somatic items in measuring depression. Fifteen breast cancer prospective studies were reviewed. Results: While twelve of the studies found positive associations between depression and breast cancer development, three studies found negative associations. With regards …

Individual And Developmental Differences In Susceptibility To The Irrelevant Speech Effect., Amanda Frances O'Bryan

Electronic Theses and Dissertations

The Irrelevant Speech Effect (ISE) is a phenomenon in which the presentation of auditory materials (typically speech) impairs the serial recall of visually presented materials, either digits or letters. Although this effect has been replicated in a large number of studies, a wide range of individual differences in susceptibility to the auditory distracters has been found. The current study investigates four possible determinants of individual differences of the ISE: (1) The sequence length of the short-term memory (STM) task, (2) the content of the STM task and auditory distracter, (3) the STM capacity of the individual, and (4) developmental differences. …

Perceptions Of Gender In Young Consumers Of Animated Films., Katherine Barnes 1980-

Electronic Theses and Dissertations

The purpose of this study was to investigate the gender stereotyping of two animated films by boys and girls (N=25). Based on Bern's (1983) gender schema theory, it was hypothesized that children would stereotype Aladdin as being for males and Pocahontas as being for females, based on the gender of the lead character. Interviews with participants (five to six years old) revealed that they did not gender stereotype the two films. A majority of both boys and girls liked the two films and felt they were for boys and girls. However, they did not think a girl could rescue another …

Malaysia's Transitional Moment? : Democratic Transition Theory And The Problem Of Malaysian Exceptionalism., Jason P. Abbott

Faculty Scholarship

Many theorists of democratization transition have, either explicitly or implicitly, a teleological concept of political progress, liberalization and reform. For such theorists, countries such as Malaysia are therefore in transition towards substantive 'full' liberal democracy. Taken in this light, the significant advances by opposition political parties in the 2008 federal and state elections in Malaysia represent a major advance towards this end goal. While many have highlighted that Malaysia may in fact be an exception to this rule, this paper contends instead that the Malaysian case study challenges the central tenets of democratic transition more profoundly. Indeed, since independence the …