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Synthesis Of A Drug Delivery Vehicle For Cancer Treatment Utilizing Dna-Functionalized Gold Nanoparticles., Tyler Brann
Synthesis Of A Drug Delivery Vehicle For Cancer Treatment Utilizing Dna-Functionalized Gold Nanoparticles., Tyler Brann
Electronic Theses and Dissertations
The treatment of cancer with chemotherapeutic agents has made great strides in the last few decades but still introduces major systemic side effects. The potent drugs needed to kill cancer cells often cause irreparable damage to otherwise healthy organs leading to further morbidity and mortality. A therapy with intrinsic selective properties and/or an inducible activation has the potential to change the way cancer can be treated. Gold nanoparticles (GNPs) are biocompatible and chemically versatile tools that can be readily functionalized to serve as molecular vehicles. The ability of these particles to strongly absorb light with wavelengths in the therapeutic window …
Investigation Of Stabilization Mechanisms For Colloidal Suspension Using Nanoparticles., Qingwen He
Investigation Of Stabilization Mechanisms For Colloidal Suspension Using Nanoparticles., Qingwen He
Electronic Theses and Dissertations
Over the past decade, charged nanoparticles have been found to enhance the stability of colloidal suspensions. One promising explanation of this stabilization mechanism is “Nanoparticle Haloing”- the formation of a non-adsorbing nanoparticle layer surrounding neutral colloids that would induce an effective electrostatic repulsion between them. The objective of this work was to investigate the effect of additional charged nanoparticles on the interaction between neural colloids in nanoparticle-regulated complex fluids. Firstly, colloidal probe Atomic Force Microscopy (CP-AFM) is used to directly measure the interaction force in such system with nanoparticle volume fractions varying from 10-6 to 10-2. It is found that …
Investigation Of Thiol Derivatized Gold Nanoparticle Sensors For Gas Analysis., Jared S. Stephens 1990-
Investigation Of Thiol Derivatized Gold Nanoparticle Sensors For Gas Analysis., Jared S. Stephens 1990-
Electronic Theses and Dissertations
Analysis of volatile organic compounds (VOCs) in air and exhaled breath by sensor array is a very useful testing technique. It can provide non-invasive, fast, inexpensive testing for many diseases. Breath analysis has been very successful in identifying cancer and other diseases by using a chemiresistor sensor or array with gold nanoparticles to detect biomarkers. Acetone is a biomarker for diabetes and having a portable testing device could help to monitor diabetic and therapeutic progress. An advantage to this testing method is it is conducted at room temperature instead of 200 degrees Celsius. The objective of this research is to …
Development Of A Light-Powered Microstructure : Enhancing Thermal Actuation With Near-Infrared Absorbent Gold Nanoparticles., Thomas Matthew Lucas
Development Of A Light-Powered Microstructure : Enhancing Thermal Actuation With Near-Infrared Absorbent Gold Nanoparticles., Thomas Matthew Lucas
Electronic Theses and Dissertations
Development of microscale actuating technologies has considerably added to the toolset for interacting with natural components at the cellular level. Small-scale actuators and switches have potential in areas such as microscale pumping and particle manipulation. Thermal actuation has been used with asymmetric geometry to create large deflections with high force relative to electrostatically driven systems. However, many thermally based techniques require a physical connection for power and operate outside the temperature range conducive for biological studies and medical applications. The work presented here describes the design of an out-of-plane bistable switch that responds to near-infrared light with wavelength-specific response. In …