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Novel Applications Of Machine Learning In Bioinformatics, Yi Zhang Jan 2019

Novel Applications Of Machine Learning In Bioinformatics, Yi Zhang

Theses and Dissertations--Computer Science

Technological advances in next-generation sequencing and biomedical imaging have led to a rapid increase in biomedical data dimension and acquisition rate, which is challenging the conventional data analysis strategies. Modern machine learning techniques promise to leverage large data sets for finding hidden patterns within them, and for making accurate predictions. This dissertation aims to design novel machine learning-based models to transform biomedical big data into valuable biological insights. The research presented in this dissertation focuses on three bioinformatics domains: splice junction classification, gene regulatory network reconstruction, and lesion detection in mammograms.

A critical step in defining gene structures and mRNA …


Learning To Map The Visual And Auditory World, Tawfiq Salem Jan 2019

Learning To Map The Visual And Auditory World, Tawfiq Salem

Theses and Dissertations--Computer Science

The appearance of the world varies dramatically not only from place to place but also from hour to hour and month to month. Billions of images that capture this complex relationship are uploaded to social-media websites every day and often are associated with precise time and location metadata. This rich source of data can be beneficial to improve our understanding of the globe. In this work, we propose a general framework that uses these publicly available images for constructing dense maps of different ground-level attributes from overhead imagery. In particular, we use well-defined probabilistic models and a weakly-supervised, multi-task training …


Weld Penetration Identification Based On Convolutional Neural Network, Chao Li Jan 2019

Weld Penetration Identification Based On Convolutional Neural Network, Chao Li

Theses and Dissertations--Electrical and Computer Engineering

Weld joint penetration determination is the key factor in welding process control area. Not only has it directly affected the weld joint mechanical properties, like fatigue for example. It also requires much of human intelligence, which either complex modeling or rich of welding experience. Therefore, weld penetration status identification has become the obstacle for intelligent welding system. In this dissertation, an innovative method has been proposed to detect the weld joint penetration status using machine-learning algorithms.

A GTAW welding system is firstly built. Project a dot-structured laser pattern onto the weld pool surface during welding process, the reflected laser pattern …