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A Changing Perspective On The Role Of Neuroinflammation In Alzheimer's Disease, Donna M. Wilcock
A Changing Perspective On The Role Of Neuroinflammation In Alzheimer's Disease, Donna M. Wilcock
Physiology Faculty Publications
Alzheimer's disease (AD) is a complex, neurodegenerative disorder characterized by the presence of amyloid plaques and neurofibrillary tangles in the brain. Glial cells, particularly microglial cells, react to the presence of the amyloid plaques and neurofibrillary tangles producing an inflammatory response. While once considered immunologically privileged due to the blood-brain barrier, it is now understood that the glial cells of the brain are capable of complex inflammatory responses. This paper will discuss the published literature regarding the diverse roles of neuroinflammation in the modulation of AD pathologies. These data will then be related to the well-characterized macrophage phenotypes. The conclusion …
[Review Of] Disaster Response And Planning For Libraries, Jennifer A. Bartlett
[Review Of] Disaster Response And Planning For Libraries, Jennifer A. Bartlett
Library Faculty and Staff Publications
No abstract provided.