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Dietary Consumptions Pattern And Risk Of Oral Cancer: A Malaysian Scenario, Helen-Ng L. C., Ishak I. A., Ghani W. M. N., Marhazlinda J., Norlida A., Rosnah Binti Zain

Prof. Dr. Rosnah Binti Zain

Introduction: The risk of cancer has been extensively investigated with the intake of single food items but food consumption in an individual is usually complex, made up by combinations of different food items. This study aims to identify dietary patterns of Malaysians, and establishing relationship between dietary pattern and oral cancer risk. Methods A hospital-based, case-control study was conducted on 300 Malaysians who seek treatment at participating hospitals between January 2003 and December 2010. The subjects consisted of 150 cases and 150 controls that were matched for gender, age (5 years) and ethnicity. Dietary intake was measured using Food Frequency …

Association Between Retinol And Vitamin C With The Risk Of Oral Cancer - A Case-Control Study, Vimmitra A., Razak I. A., Helen-Ng L. C., Ghani W. M. N., Abdullah N., Rosnah Binti Zain

Prof. Dr. Rosnah Binti Zain

Introduction: Dietary intake has been hypothesized to be associated with various diseases including oral cancer. According to studies worldwide, imbalanced diet and nutrient deficiency have been attributed to promote oral malignancies. However, the function of specific nutrients in preventing oral cancer remains largely undefined. This study aims to investigate the association between intake of retinol and vitamin C with the risk of oral cancer. Materials and methods: Dietary intake data was collected from 8 participating hospitals throughout Malaysia using a validated foodfrequency questionnaire (FFQ). Intake of retinol and vitamin C were computed using the Nutriemart software. This case-control study included …

Saving The Leftovers: Models For Banking Cord Blood Stem Cells, Kimberly J. Cogdell

Kimberly J Cogdell

This article draws an interesting comparison between material placed on the curb to be collected as garbage and the material (cord blood stem cells) removed during childbirth to be discarded by the hospital. The comparison is made based on the California v. Greenwood decision and deals with expectations of privacy in materials placed on the curbside as trash; search and seizure of materials obtained from a warrantless search and whether the use of this material violated the Fourth Amendment.

The use of embryonic stem cells is a highly publicized, politically-charged topic which implicates many ethical, legal and moral issues. But …

Proliferative And Apoptotic Activity At The Tumour Invasive Front In Oral Squamous Cell Carcinoma, W.C. Ngeow, R. B. Zain, Z. Abidin, K. S. Phaik, S. Kumar

Wei Cheong Ngeow

Introduction: the tumour invasive front of squamous cell carcinoma (OSCC) has long been recognized as an important area which harbour prognostic information. The aim of the present study was to describe the expression of K1-67, MDM2 and Bcl-2 at the tumour invasive front in the buccal mucosa and also to investigate whether there is any association between the expression of K1-67, MDM2 and Bcl-2 with the certain sociodemographic characteristics, clinical and histopathological parameters. Materials and Methods: The sample of this study consisted of 31 biopsy cases of OSCC from the buccal mucosa. Immunohistochemistry was used with specific antibodies to K1-67, …

Periodontal Status And Treatment Needs Among Indian Estate Population, Ali T. T., Razak I. A., Rosnah Binti Zain

Prof. Dr. Rosnah Binti Zain

The aim of this study was to determine the periodontal status and treatment needs among the Indian estate population. The Community Periodontal Index of Treatment Needs was used to obtained clinical data on 208 Indian subjects residing in three estates in the state of Selangor. The prevalence of periodontal disease among the subjects was 100%. Less than 1% of the subjects had bleeding on probing as the highest CPITN score. About 97% of the subjects showed evidence of periodontal pocket of 4mm or more. Of these, half showed pocketing of 6mm or more. No statistically significant difference (p> 0.05) was …