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A Full Factorial Analysis Of Polymerization Conditions Of Sodium Alginate Beads To Determine The Effect On Diffusivity And Concentration Limit Of Tryptophan And Glucose, Allison Schulkins
A Full Factorial Analysis Of Polymerization Conditions Of Sodium Alginate Beads To Determine The Effect On Diffusivity And Concentration Limit Of Tryptophan And Glucose, Allison Schulkins
Master's Theses
The purpose of this work is to develop an experimental setup with associated mathematical analysis to analyze the changes in diffusivity through calcium alginate gel beads made under different polymerization conditions. The diffusivity of the solutes glucose and tryptophan was calculated by measuring the concentration change over time as solute diffused out of the alginate spheres and into the bulk. The alginate beads were generated using different polymerization conditions following a two-level, three-factor, full-factorial matrix with alginate concentration, cross-linker concentration, and cross-linking time as the factors. The diffusivities showed variations between different conditions, which were analyzed to determine the main …