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Application Of Icp Rie Techniques To Produce Cnt Arrays, Mujtaba Yar Khan Siddiqui
Application Of Icp Rie Techniques To Produce Cnt Arrays, Mujtaba Yar Khan Siddiqui
Theses
Introducing biomolecules into cells is an important process in the field of gene therapy and in developing cures for debilitating illnesses such as HIV and cancer. However, the currently used methods for cellular transfection are slow, inefficient and expensive, causing them to be restrictive. A solution to this problem would be the carbon nanotube (CNT) array devices developed by our research group, which have been shown to be highly efficient at transporting biomolecules into cells. In the current manufacturing process, a sacrificial template with vertically aligned nanopores is used to deposit carbon in, the template then is etched away to …
Measuring Diffusion Through Carbon Nanotube Arrays With Fluorescent Spectroscopy, Michael Machold
Measuring Diffusion Through Carbon Nanotube Arrays With Fluorescent Spectroscopy, Michael Machold
Theses
Carbon nanotube (CNT) arrays are emerging as versatile nanostructures that can be used in many applications including gene transfection technology. To understand the transport of molecules through an array of CNTs, diffusion of molecules was studied experimentally and analytically. A procedure using fluorescent spectroscopy was developed to measure the concentration change of fluorescein salt in a two-reservoir system separated by a CNT array. Experiments were conducted to measure how changing the initial concentration gradient and reservoir volume size impacted the diffusivity of the system. For 2 mL reservoirs, diffusivities were measured between 2.56*10^(-11) m^2/s and 3.51*10^(-11) m^2/s. Diffusivities were measured …