Digital Commons Network^™

Impact Of Dietary Modification On Aflatoxicosis In Poultry, Xi Chen

Open Access Dissertations

Aflatoxin contamination in feed and feed ingredients is of high worldwide prevalence, posing serious risks to the livestock industry. A series of studies were conducted to better understand the comprehensive impact of aflatoxicosis and its interrelationships with dietary modifications in broiler chicks and ducks. Results of these studies emphasize the many factors that the severity of aflatoxicosis depends on, including animal species, age, presence of mycotoxin adsorbent, and concentration of major dietary nutrients. Exposure to 2 mg/kg cultured AFB1 led to reduced feed intake, BW gain, depressed feed efficiency, increased relative liver weight, negatively affected serum measures and complement activity, …

Utilization Of Ferrioxamine Microarrays For The Rapid Detection Of Pathogenic Bacteria, Nigam Bir Arora

Open Access Dissertations

Siderophores are low-molecular weight species utilized by bacteria for the sequestration of iron, an essential nutrient. Siderophores and their cognate receptors are considered to be virulence factors, due to their prominent role in pathogenicity. The work presented here focuses on ferrioxamine (FOx) as an “immutable” ligand for pathogen detection. A number of bacterial strains expressing high-affinity FOx receptors were identified by a proteomic BLAST search, and screened against microarrays patterned with FOx conjugates for detection using label-free optical imaging. Aspects such as inkjet printing and surface chemistry, iron-limiting conditions and bacterial selection protocols, and linker conjugate design were addressed and …

Modeling For Thermal Resistance Of Non-O157 Shiga Toxin Producing Escherichia Coli In Ground Beef, Jagpinder S. Brar

Open Access Dissertations

Predictive models in microbiology are used for estimating the growth or survival of microorganism in a set of environmental conditions. A validated predictive model provides an alternative to extensive survival and shelf life studies. In this study, a predictive inactivation model for non-O157 shiga toxin producing Escherichia coli (STEC) in ground beef was developed. Six strains of non-O157 STEC; E. coli O26:H1, E. coli O45:H2, E. coli O103:H2, E. coli O111:H8, E. coli O121:H9, and E. coli O145: nonmotile, has similar pathogenicity as E. coli O157:H7 and can cause serious food borne illnesses. These pathogens are considered as an adulterant …

Perceval's Sister And Juliet Capulet As Disruptive Guides In Spiritual Quests, Joanna Benskin

Open Access Dissertations

Perceval’s sister in Sir Thomas Malory’s Le Morte Darthur and Juliet in William Shakespeare’s Romeo and Juliet act as disruptive guides in spiritual quests by contradicting the expectations placed on them as women characters.

Though women are banned from the quest for the Holy Grail, Perceval’s sister accompanies the Grail knights as an authoritative spiritual guide and a symbol of the Eucharist. Previous critics have not recognized Perceval’s sister as a fundamental disruption to the systemic misogyny of the Morte or her Eucharistic significance. She challenges both the chivalric misogyny that sees her as an object of rescue and the …

Hybrid Stm/Htm For Nested Transactions In Java, Keith G. Chapman

Open Access Dissertations

Transactional memory (TM) has long been advocated as a promising pathway to more automated concurrency control for scaling concurrent programs running on parallel hardware. Software TM (STM) has the benefit of being able to run general transactional programs, but at the significant cost of overheads imposed to log memory accesses, mediate access conflicts, and maintain other transaction metadata. Recently, hardware manufacturers have begun to offer commodity hardware TM (HTM) support in their processors wherein the transaction metadata is maintained “for free” in hardware. However, HTM approaches are only best-effort: they cannot successfully run all transactional programs, whether because of hardware …

Authentic Science In Education: Studies In Course-Based Research At The United States Military Academy, Anthony M. Chase

Open Access Dissertations

This dissertation consists of two studies at the United States Military Academy. Both studies involve the use of Course-based Undergraduate Research Experiences (CUREs). These experiences give students the ability to engage in undergraduate research at an early point in their academic career by replacing traditional laboratory activities with semester-long research projects. Both studies show an implementation of this type of instruction from the Center for Authentic Science Practice in Education (CASPiE). Study 1 shows the specific method of implementation at the military academy and explores learning-based outcomes. Primarily the outcome of critical thinking is demonstrated. Critical thinking is a construct …

Teoria De La Mente Y Sociedad En La Narrativa Policiaca De Lorenzo Silva Y Francisco Garcia Pavon: Estereotipos, Roles De Genero Y Minorias, Jesus Castro Gorfti

Open Access Dissertations

Spanish:

The purpose of this study is to utilize certain aspects of cognitive psychology as a framework to analyze the police procedural novels of two Spanish authors: Francisco García Pavón and Lorenzo Silva. Specifically, we will focus on two main aspects of the mind studied by the cognitive sciences: Theory of Mind and metarepresentations. Theory of Mind (ToM) refers to the capacity that human beings have to attribute mental states to other humans, as well as oneself, based on their bodily and facial gestures. The concept of metarepresentation refers to the ability of humans to keep track of who said …

Visual Analytics Of Location-Based Social Networks For Decision Support, Junghoon Chae

Open Access Dissertations

Recent advances in technology have enabled people to add location information to social networks called Location-Based Social Networks (LBSNs) where people share their communication and whereabouts not only in their daily lives, but also during abnormal situations, such as crisis events. However, since the volume of the data exceeds the boundaries of human analytical capabilities, it is almost impossible to perform a straightforward qualitative analysis of the data. The emerging field of visual analytics has been introduced to tackle such challenges by integrating the approaches from statistical data analysis and human computer interaction into highly interactive visual environments. Based on …

Exploring The Potential Impacts Of Climate Change On North America's Laurentian Great Lakes Tourism Sector, Natalie Chin

Open Access Dissertations

Climate change is one of the major challenges facing the global hospitality and tourism sector in the coming century and, given the important role that weather and climate play in all aspects of the tourism experience, tourism businesses owners need to start thinking about and enacting climate change adaptation strategies now. This work has utilized a combination of social science and physical science methods to (1) understand how the Great Lakes tourism sector could be impacted by climate change and (2) provide some insights into how researchers can help business owners prepare for these potential impacts. Overall, the results of …

Functional And Structural Characterization Of The Mevalonate Diphosphate Decarboxylase And The Isopentenyl Diphosphate Isomerase From Enterococcus Faecalis, Chun-Liang Chen

Open Access Dissertations

Enterococcus faecalis causes a diverse range of nosocomial infections (in wounds, the gastrointestinal tract, the blood stream and the endocardium), and multidrug-resistant strains have become a serious issue across countries. Vancomycin, a FDA-approved drug for the disruption of the bacterial cell wall biosynthesis, has been utilized to treat infectious diseases caused by Enterococci; however, the prevalence of vancomycin-resistant enterococci (VRE) threatens communities all over the world. We aim at developing novel therapeutic strategies to control bacterial growth of Enterococci, and we focus on targeting two essential enzymes involved in poly-isoprenoid biosynthesis in Enterococcus faecalis; one is the mevalonate diphosphate decarboxylase …

Fea Methodology For System-Level Redundancy Evaluation: Application To Non-Composite Steel Bridges, Francisco Javier Bonachera Martin

Open Access Dissertations

Currently, all steel bridges with members designated as Fracture Critical Members (FCMs) are required to undergo hands-on inspections every 24 months. A FCM is a primary steel tension member (or portion of) which failure results in collapse or loss of serviceability of a bridge. However, presently, there are no codified procedures used to evaluate system-level redundancy in steel bridges. In this dissertation, finite element analysis (FEA) procedures, techniques and inputs were researched in order to develop bridge models that account for the mechanisms that lead to redundant capacity after the failure of a primary steel member. These mechanisms include partial …

Sounding Sacred: The Adoption Of Biblical Archaisms In The Book Of Mormon And Other 19th Century Texts, Gregory A. Bowen

Open Access Dissertations

The Book of Mormon is a text published in 1830 and considered a sacred work of scripture by adherents of the Latter-day Saint movement. Although written 200 years later, it exhibits many linguistic features of the King James translation of the Bible. Such stylistic imitation has been little studied, though a notable exception is Sigelman & Jacoby (1996).

Three hypotheses are considered: that this is a feature of 19th century religious texts, and the Book of Mormon adopts the style of its genre as a religious text; that this is a feature of translations of ancient texts, and the Book …

Combinatorial Algorithms For Perturbation Theory And Application On Quantum Computing, Yudong Cao

Open Access Dissertations

Quantum computing is an emerging area between computer science and physics. Numerous problems in quantum computing involve quantum many-body interactions. This dissertation concerns the problem of simulating arbitrary quantum many-body interactions using realistic two-body interactions. To address this issue, a general class of techniques called perturbative reductions (or perturbative gadgets) is adopted from quantum complexity theory and in this dissertation these techniques are improved for experimental considerations. The idea of perturbative reduction is based on the mathematical machinery of perturbation theory in quantum physics. A central theme of this dissertation is then to analyze the combinatorial structure of the perturbation …

A Descriptive Case Study: Investigating The Implementation Of Web Based, Automated Grading And Tutorial Software In A Freshman Computer Literacy Course, Glen J. Coulthard

Open Access Dissertations

Students in higher education require satisfactory computer skills to be successful. While today’s students may have greater exposure to technology, research shows that their actual computer knowledge and skills are superficial and narrow. As a result, the freshman computer literacy course remains an important curricular component. This study investigates the implementation of an innovative Web-based technology for delivering software proficiency training for Microsoft Office. Building upon decades of end-user computing satisfaction and technology acceptance research, the purpose of the study is to describe the instructor and student experiences that result from the implementation and use of MyITLab educational software. The …

The Effects Of Chloride-Based Deicing Chemicals On Degradation Of Portland Cement Mortars With Alkali Reactive Aggregate, Charles Yicheng Chiu

Open Access Dissertations

The assessment of the influence of deicing chemicals on alkali reactivity of aggregates is still an area of active research, particularly with respect to the combined effects of long-term exposure to deicers, freezing and thawing cycles, and wetting and drying cycles. In order to develop a more comprehensive view of these topics, the present study was conducted in three phases. The focus of the first phase was on studying the effects of the chloride-based deicers on the alkali silica reaction (ASR) using accelerated test methods (i.e. the test was performed at high temperature (80 °C) as per modified ASTM C1260). …

The Role Of African Leafy Vegetables In Food Security, Marcia M. Croft

Open Access Dissertations

African leafy vegetables (ALVs) are a diverse set of crops grown across sub-Saharan Africa. They have been a staple of traditional diets and contain many critical micronutrients but their importance has been largely ignored by researchers and policymakers at the expense of imported crops. Availability, accessibility, and utilization of ALVs are limited by factors across the supply chain. This research investigated seed systems, drought tolerance, hydroponic production, market barriers, consumer preference, and the impact of gender as related to ALVs. We found that ALVs play an important role in food security and that critical differences exist between formal and informal …

The Development And Evaluation Of A Lean Six Sigma Advanced Manufacturing Methodologies Course For Aeronautical Engineering Technology Curriculum, John Michael Davis

Open Access Dissertations

Successful completion of the Lean Six Sigma advanced manufacturing methodologies practicum course provides undergraduate Aeronautical Engineering Technology (AET) students with the experience and knowledge appropriate to perform successfully in an advanced manufacturing environment. Therefore, the purpose of this study was to determine (a) Did the knowledge level of AET students increase following exposure to Lean Six Sigma and completion of the advanced manufacturing methodologies course? and (b) Did the course meet the AET students’ expectations following participation in the Lean Six Sigma advanced manufacturing course? The expected outcomes of the course included:

1. AET students will have the competencies to …

The Association Between Tolerance For Ambiguity And Fear Of Negative Evaluation: A Study Of Engineering Technology Capstone Courses, Sergey I. Dubikovsky

Open Access Dissertations

For many students in engineering and engineering technology programs in the US, senior capstone design courses require students to form a team, define a problem, and find a feasible technical solution to address this problem. Students must integrate the knowledge and skills acquired during their studies at the college or university level. These truly integrative design activities do not have a single “correct” solution. Instead, there is an array of solutions, many of which could be used to achieve the final result. This ambiguity can cause students to experience anxiety during the projects.

This study examined the main topics: • …

Bad Girls In Corsets: Women And The Transgressive Body In The Nineteenth Century, Colleen Warwick Green

Open Access Dissertations

Women, and their bodies, posed an increasing anxiety for Victorian society. Culturally and outwardly, the Victorian era strove to maintain a level of decorum that, increasingly, the nineteenth-century woman were, rebelling against. The urge for women to break through social barriers and constraints binding them to the century created a divergence in thought from the traditional mores of the past, in turn affecting the ways in which womens’ bodies were portrayed, displayed and manipulated by the authors and artists of the century.

As women entered actively entered into spaces once closed to them, they furthered the rift of uncertainty and …

Nanoparticle Toxicity And Molecular Mechanisms In Fish: A Case Study With Silver Nanoparticles, Jiejun Gao

Open Access Dissertations

Nanoparticles (NPs) are widely used in a myriad of commercial and industrial products making their entry to the environment a likely event. NPs have unique physical-chemical properties that result from their small size and high surface area to volume ratio, making them highly reactive and potentially toxic. In Chapter 1, we summarize the effects and mechanisms of metal-based NPs on the vascular system. In vitro studies have shown that NPs are anti-angiogenic because they cause inflammation, oxidative stress, and apoptosis of endothelial cells resulting in increased permeability and decreased proliferation and migration. Whole animal studies examining the effects of NPs …

How Training Set And Prior Knowledge Affect Preschoolers' Perception Of Quantity And Early Number Learning, Arum Han

Open Access Dissertations

This dissertation examines how training on the iPad can improve children’s quantity recognition, and whether different types of training might be warranted for children with different levels of experience. Study 1 tested the effects of multiple exemplar training (3 cars / 3 apples / 3 ducks, etc.) versus single exemplar training (3 cars / 3 cars / 3 cars, etc.) in recognizing quantities. For children just learning to recognize quantities (0-2 knowers), training with multiple exemplars was most effective for quantities three and four. For 3-6 knower children, single exemplar training was most effective for learning quantities five and six. …

Thermomechanical Properties Of Novel Lanthanum Zirconate Based Thermal Barrier Coatings - An Integrated Experimental And Modeling Study, Xingye Guo

Open Access Dissertations

Thermal barrier coatings (TBCs) are refractory materials deposited on gas turbine components, which provide thermal protection for metallic components at operating conditions. The current state-of-art TBC material is yttria-stabilized zirconia (YSZ), whose service temperature is limited to 1200 celsius, due to sintering and phase transition at higher temperatures. In comparison, lanthanum zirconate (La2Zr2O7, LZ) has become a promising candidate material for TBCs due to its lower thermal conductivity and higher phase stability compared to YSZ.

The primary objective of this thesis is to design a novel robust LZ-based TBC system suitable for applications beyond 1200 celsius. Due to LZ’s low …

Interplanetary Mission Design With Applications To Guidance And Optimal Control Of Aero-Assisted Trajectories, Peter J. Edelman

Open Access Dissertations

A method for finding optimal aerogravity-assist tours of the solar system is developed using indirect methods. Two cost functionals are used in the optimization; finding the minimum required maximum lift-to-drag ratio, with and without a convective heating-rate path constraint, and the path which provides the minimum total stagnation point convective heat load. It is found that using present or near-future thermal protection system materials will suffice for certain aerogravity assist trajectories at Mars. Minimum heat load optimal trajectories are found for aerocapture maneuvers at Uranus and Neptune. With a large radius, and short rotational periods, atmospheric rotation must be taken …

Finding The Ghost With The Machine: Breaking Through The Assessment Center Validity Ceiling By Exploring Decisional Processes Using New Sources Of Behavioral Data Within Virtual Assessments, Brett W. Guidry

Open Access Dissertations

Decades of assessment center (AC) research has resulted in an inevitable “validity ceiling” whereby increasing the validity of the AC method is becoming increasingly difficult. To overcome this challenge, new avenues for collecting and evaluating AC participant behaviors must be explored, with a particular focus on overcoming the inherent limitations of human observation—a hallmark of the AC method. This study examines detailed logs of AC participant behaviors captured automatically and unobtrusively during a computer-based simulation assessment. Using a decision making framework, basic characteristics of the new behavioral data are tested against existing theories of decisional efficacy. The construct-related validity of …

Statistical Modeling And Simulation Of Variability And Reliability Of Cmos Technology, Khaled Hassan Md

Open Access Dissertations

The introduction of High-κ Metal Gate transistors led to higher integration density, low leakage current, and faster switching speed. However, this transition in technology roadmap brought about new failure mechanisms such as Positive Bias Temperature Instability and Stress Induced Leakage Current. In addition, the relentless downscaling of devices to keep up with Moore's law has significantly increased the time-zero variability caused by Random Dopant Fluctuation, Mean Gate Length Deviation, and Line Edge Roughness. Because of their possible correlation with time dependent aging effects, the quantification of reliability has become more complex than ever. To that effect, we propose a framework …

Two-Dimensional Electronics And Optoelectronics: From Materials Syntheses To Device Applications, Yexin Deng

Open Access Dissertations

The current research on semiconductor device has pushed the scaling of the devices into sub-10 nanometers (nm) regime. While most of the current devices are made on silicon germanium, and III-V materials, people are looking for new materials for use in novel semiconductor devices: either for use in extremely scaled device in sub-10 or even sub-5 nm devices, or for use in other situations such as flexible electronics or low power and lower cost IoT (Internet of Things) applications.

Two-dimensional (2D) materials have attracted extensive research interests in their physical, chemical and mechanical properties.Since the discovery of graphene, which a …

Syk Promotes Tgf-Beta-Induced P-Body Clearance In Breast Cancer Cells Through The Enhancement Of Autophagy, Shana D. Hardy

Open Access Dissertations

SYK is a protein tyrosine kinase that plays an essential role in the development and activation of immune cells. Its expression, however, is not limited to immune cells. SYK is expressed in a variety of epithelial cell types and epithelial-derived tumors. Reports regarding the role of SYK expression in these diverse cell types and tumors have been opposing. In breast cancer, SYK expression has been overwhelmingly associated with tumor suppression. The loss of Syk expression is observed in invasive breast carcinoma tissue and cell lines and the reintroduction of Syk into metastatic breast cancer cells suppresses tumor growth and metastasis. …

Effective Memory Management For Mobile Environments, Ahmed Mohamed Abd-Elhaffiez Hussein

Open Access Dissertations

Smartphones, tablets, and other mobile devices exhibit vastly different constraints compared to regular or classic computing environments like desktops, laptops, or servers. Mobile devices run dozens of so-called “apps” hosted by independent virtual machines (VM). All these VMs run concurrently and each VM deploys purely local heuristics to organize resources like memory, performance, and power. Such a design causes conflicts across all layers of the software stack, calling for the evaluation of VMs and the optimization techniques specific for mobile frameworks.

In this dissertation, we study the design of managed runtime systems for mobile platforms. More specifically, we deepen the …

Hydrocode Modeling Of Oblique Impacts Into Terrestrial Planets, Jordan D. Kendall

Open Access Dissertations

The abundance of moderately siderophile elements (“iron-loving”; e.g., Co, Ni) in the Earth’s mantle is 10 to 100 times larger than predicted by chemical equilibrium between silicate melt and iron at low pressure, but it does match expectation for equilibrium at high pressure and temperature. Recent studies of differentiated planetesimal impacts assume that planetesimal cores survive the impact intact as concentrated masses that passively settle from a zero initial velocity and undergo turbulent entrainment in a global magma ocean; under these conditions, cores greater than 10 km in diameter do not fully mix without a sufficiently deep magma ocean. I …

The Application Of Natural Language Processing To Open Source Intelligence For Ontology Development In The Advanced Persistent Threat Domain, Corey T. Holzer

Open Access Dissertations

Over the past decade, the Advanced Persistent Threat (APT) has risen to forefront of cybersecurity threats. APTs are a major contributor to the billions of dollars lost by corporations around the world annually. The threat is significant enough that the Navy Cyber Power 2020 plan identified them as a “must mitigate” threat in order to ensure the security of its warfighting network.

Reports, white papers, and various other open source materials offer a plethora of information to cybersecurity professionals regarding these APT attacks and the organizations behind them but mining and correlating information out of these various sources needs the …