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Generation Of A Fully Human Scfv That Binds Tumor-Specific Glycoforms, Zhongpeng Lu, Kalika Kamat, Blake P. Johnson, Catherin C. Yin, Nathalie Scholler, Karen L. Abbott
Generation Of A Fully Human Scfv That Binds Tumor-Specific Glycoforms, Zhongpeng Lu, Kalika Kamat, Blake P. Johnson, Catherin C. Yin, Nathalie Scholler, Karen L. Abbott
Articles
Tumor-specific glycosylation changes are an attractive target for the development of diagnostic and therapeutic applications. Periostin is a glycoprotein with high expression in many tumors of epithelial origin including ovarian cancer. Strategies to target the peptide portion of periostin as a diagnostic or therapeutic biomarker for cancer are limited due to increased expression of periostin in non-cancerous inflammatory conditions. Here, we have screened for antibody fragments that recognize the tumor-specific glycosylation present on glycoforms of periostin containing bisecting N-glycans in ovarian cancer using a yeast-display library of antibody fragments, while subtracting those that bind to the periostin protein with glycoforms …
French Place Names In Clark County, Arkansas, Joe Jeffers
French Place Names In Clark County, Arkansas, Joe Jeffers
Articles
French place names are common in Arkansas, especially in south Arkansas, where after the French explorers left, French trappers and settlers from Canada moved in. Some of those names remain unchanged from the original French. General usage and English speaking settlers modified others. Clark County was one of five counties established in the Arkansas Territory. Its boundaries changed five times before reaching its present form in 1877. This article explores French place names in today’s Clark County and in the original Clark County formed in 1818.
The Wiley Funeral Home Records At Ouachita Baptist University, Lisa K. Speer
The Wiley Funeral Home Records At Ouachita Baptist University, Lisa K. Speer
Articles
In 2009, Ouachita Baptist University's Special Collections and Archives received a set of records from the Wiley Funeral Home (now Mitchell Funeral Home) of Arkadelphia, containing death certificates, burial transit permits, and funeral insurance records kept between 1941-1968. The records document the lives of several thousand African Americans who were either residents of Clark County or whose funerals were handled by Wiley Funeral Home.
A Geological History Of Clark County, Arkansas, Joe Jeffers
A Geological History Of Clark County, Arkansas, Joe Jeffers
Articles
The geological history of Clark County is described ranging from 500 million years ago to the present. One-third of present-day Clark County is in the Ouachita Mountains, two-thirds is in the Coastal Plain. The formation of the Ouachita Mountains is described, as is the cretaceous formations that led to biological fossils. Historic mining of minerals is also discussed. For the more technically inclined, a detailed description of the geological formations of the county is included near the end.
Clark County, Arkansas: The Garden Spot Of The Sunny South, Lisa K. Speer
Clark County, Arkansas: The Garden Spot Of The Sunny South, Lisa K. Speer
Articles
Presented here is a typescript of a pamphlet produced and distributed circa 1877 by the St. Louis, Iron Mountain, and Southern Railway to promote settlement in Clark County. The original pamphlet is housed in the collections of the Arkansas State Archives.
100 Years Ago: Front-Page Stories From Arkadelphia's Southern Standard, Lisa K. Speer
100 Years Ago: Front-Page Stories From Arkadelphia's Southern Standard, Lisa K. Speer
Articles
The following news items were extracted from the front pages of Arkadelphia's Southern Standard weekly newspaper of 1919. The articles illustrate the variety of news published by the paper and offer glimpses into life in early 20th-century Clark County. The return to normalcy following the end of a world war; agricultural and economic development of the county; and moonshining were just a few of the themes that ran through the news that made the front pages of 1919.