Digital Commons Network^™

Structural Studies On A Mitochondrial Glyoxalase Ii, Gishanthi P. K. Marasinghe, Ian M. Sander, Brian Bennett, Gopal R. Periyannan, Ke-Wu Yang, Christopher A. Makaroff, Michael W. Crowder

Physics Faculty Research and Publications

Glyoxalase 2 is a β-lactamase fold-containing enzyme that appears to be involved with cellular chemical detoxification. Although the cytoplasmic isozyme has been characterized from several organisms, essentially nothing is known about the mitochondrial proteins. As a first step in understanding the structure and function of mitochondrial glyoxalase 2 enzymes, a mitochondrial isozyme (GLX2-5) from Arabidopsis thaliana was cloned, overexpressed, purified, and characterized using metal analyses, EPR and ¹H NMR spectroscopies, and x-ray crystallography. The recombinant enzyme was shown to bind 1.04 ± 0.15 eq of iron and 1.31 ± 0.05 eq of Zn(II) and to exhibit k_cat and …

History, Collective Memory, And The Appropriation Of Martin Luther King, Jr.: Reagan's Rhetorical Legacy, Denise M. Bostdorff, Steven R. Goldzwig

College of Communication Faculty Research and Publications

This article argues that President Ronald Reagan appropriated Dr. Martin Luther King, Jr.'s words and memory to suggest equal opportunity in the United States had been largely achieved. Individuals—rather than the government—now had to take responsibility for any additional progress. By arguing that the dismantling of federal civil rights laws and social programs was actually consistent with Dr. King's words, President Reagan advanced his own agenda for civil rights in direct violation of Dr. King's intentions, while narrowing the purview of civil rights to eliminate government intervention in employment, education, and other arenas.

Space And Place In The Metropolis: Arabs And Muslims Seeking Safety, Louise Cainkar

Social and Cultural Sciences Faculty Research and Publications

No abstract provided.

Utilization Of Income Tax Credits By Low-Income Individuals, Stacy Dickert-Conlin, Katie Fitzpatrick, Andrew Hanson

Economics Faculty Research and Publications

The Internal Revenue Service-a sub-agency that exists to collect revenue-has the task of administering and enforcing a wide array of social policy: from subsidies for college and child care expenses, to creating jobs in depressed areas, and assisting welfare recipients with employment. While these new or expanded credits represent a new paradigm in the delivery of social policy, little is known about who uses these programs and, equally important, who does not use these programs. Understanding utilization is a key to understanding how effective this means of transferring income is and whether we are reaching the targeted populations. This paper …

The Stochastic Dance Of Early Hiv Infection, Stephen J. Merrill

Mathematics, Statistics and Computer Science Faculty Research and Publications

The stochastic nature of early HIV infection is described in a series of models, each of which captures aspects of the dance of HIV during the early stages of infection. It is to this highly variable target that the immune response must respond. The adaptability of the various components of the immune response is an important aspect of the system's operation, as the nature of the pathogens that the response will be required to respond to and the order in which those responses must be made cannot be known beforehand. As HIV infection has direct influence over cells responsible for …

The Fairness Doctrine Redux: Media Bias And The Rights Of Broadcasters, Erik Ugland

College of Communication Faculty Research and Publications

No abstract provided.

Valuing Earth Intrinsically And Instrumentally: A Theological Framework For Environmental Ethics, Jame Schaefer

Theology Faculty Research and Publications

Philosophers have struggled with value theory as one of the most recalcitrant problems for environmental ethics. Theologians can benefit from their efforts when retrieving and reworking notions about the goodness of creation in patristic and medieval texts, particularly those by Augustine, John Chrysostom, and Thomas Aquinas. This process yields a religiously motivated rationale for intrinsic-instrumental valuing of the physical world's constituents for themselves, their relationships to one another, and their common good that can be relevant, meaningful, and helpful for responding to ecological degradation.

Empirical Studies Of Foreign Direct Investment, Joseph P. Daniels

Economics Faculty Research and Publications

No abstract provided.

International Technology Diffusion: Effects Of Trade And Fdi, Alejandro Ciruelos, Miao Wang

Economics Faculty Research and Publications

There has been little analysis of the effect of inward FDI on international R&D diffusion, especially in LDCs, although FDI has become the core of international production and LDCs have been receiving an increasing share of world FDI over the past few decades. Using data from 57 countries from 1988 to 2001, we find that both FDI and trade serve as important channels of international technology diffusion. However, there exist heterogeneous effects of FDI in DCs and LDCs. For inward FDI to promote technology diffusion in LDCs, a certain threshold of human capital has to be reached.

Remapping Hand Movements In A Novel Geometrical Environment, Kristine M. Mosier, Robert A. Scheidt, Santiago Acosta, Ferdinando A. Mussa-Ivaldi

Biomedical Engineering Faculty Research and Publications

The issue of how the Euclidean properties of space are represented in the nervous system is a main focus in the study of visual perception, but is equally relevant to motor learning. The goal of our experiments was to investigate how the properties of space guide the remapping of motor coordination. Subjects wore an instrumented data glove that recorded the finger motions. Signals generated by the glove operated a remotely controlled endpoint: a cursor on a computer monitor. The subjects were instructed to execute movements of this endpoint with controlled motions of the fingers. This required inverting a highly redundant …

Atr-Ftir Spectroscopic Analysis Of Sorption Of Aqueous Analytes Into Polymer Coatings Used With Guided Sh-Saw Sensors, Yolanda K. Jones, Zhonghui Li, Michael M. Johnson, Fabien Josse, Jeanne Hossenlopp

Chemistry Faculty Research and Publications

Attenuated total internal reflectance Fourier transform infrared (ATR-FTIR) spectroscopy was used for the investigation of sorption of aqueous solutions of analytes into polymer coatings. A series of simple model polymers, such as poly(dimethylsiloxane), poly(epichlorhydrin), and poly(isobutylene), and films and analytes, such as aqueous solutions of ethylbenzene, xylenes, toluene, and nitrobenzene, were used to evaluate the use of ATR-FTIR spectroscopy as a screening tool for sensor development. The ratios of integrated infrared absorption bands provided a simple and efficient method for predicting trends in partition coefficients. Responses of polymer-coated guided shear horizontal surface acoustic wave (SH-SAW) sensor platforms to the series …

Intern Self-Care: An Exploratory Study Into Strategy Use And Effectiveness, Joseph A. Turner, Lisa Edwards, Iverson M. Eicken, Kayoko Yokoyama, Jennifer R. Castro, Amber Ngoc-Thuy Tran, Kristee L. Haggins

College of Education Faculty Research and Publications

In this exploratory study, 363 interns were surveyed to assess the frequency of use and effectiveness of self-care strategies used during the internship year. Among the most frequently used strategies were family and friend social support, active problem solving, and humor. The most effective strategies were family and friend social support, seeking pleasurable experiences, and humor. A strong positive relationship was found between total scores for Frequency and Effectiveness subscales, and women reported significantly more use and effectiveness of strategies. Recommendations and resources are provided for interns and internship sites that seek to further understand and encourage intern self-care.

Smoke And Mirrors: Internalizing The Magic Lantern Show In Villette, Diane Hoeveler

English Faculty Research and Publications

With considerable historical background in mind, I would like to examine a number of the stock gothic tropes, including the mysterious nun, the paintings of women, the theater scene, and the fête in Villette as examples of not simply one of last gasps of high Victorian gothicism, but also of the internalization and critique of gothic theatrical technology. As Castle observes, the "phantasmagoria should [have] become a kind of master trope in nineteenth-century romantic writing," and certainly she applies the representation in provocative ways to the symbols and imagery in Thomas Carlyle's French Revolution. In a similar fashion, I …

Combined X-Ray Diffraction And Diffuse Reflectance Analysis Of Nanocrystalline Mixed Sn(Ii) And Sn(Iv) Oxide Powders, Hongmei Deng, Jeanne Hossenlopp

Chemistry Faculty Research and Publications

Nanocrystalline mixtures of Sn(II) and Sn(IV) oxide powders, potential gas sensor materials, are synthesized via a simple precipitation route using SnCl(2) as the precursor. Materials are characterized by powder X-ray diffraction, thermogravimetric analysis, UV-visible diffuse reflectance spectroscopy (DRS), and Fourier transform infrared spectroscopy. The ratio of Sn(II)/Sn(IV) in powders precipitated at room temperature, as well as the identity of the primary Sn(II) product (SnO or Sn(6)O(4)(OH)(4)), can be varied by adjusting aging time and washing procedures. The identity of the initial Sn(II) product influences the subsequent phase composition and degree of disorder in the tetragonal SnO(2) phase obtained following sintering …

Psychometric Evaluation Of The Shared Care Instrument In A Sample Of Home Health Care Family Dyads, Margaret Sebern

College of Nursing Faculty Research and Publications

Researchers have studied negative effects of caregiving on a family caregiver; however, less is known about positive aspects of exchanging assistance for both members of a family caregiving dyad. In a previous naturalistic inquiry the author indentified a basis for studying caregiving interactions was a construct called shared care. The three components of shared care identified in the naturalistic inquiry were communication, decision making, and reciprocity. The Shared Care Instrument (SCI) was developed to measure the construct. The purpose of this study was to assess the psychometric properties of the SCI, and to assess its construct and criterion-related validity. A …

Disentangling Above‐ And Below‐Ground Competition Between Lianas And Trees In A Tropical Forest, Stefan A. Schnitzer, Mirjam E. Kuzee, Frans Bongers

Biological Sciences Faculty Research and Publications

1. Light is thought to be the most limiting resource in tropical forests, and thus above‐ground competition is commonly accepted as the mechanism that structures these communities. In many tropical forests, trees compete not only with other trees, but also with lianas, which compete aggressively for below‐ground resources and thus may limit tree growth and regeneration.
2. Using a replicated experiment, we tested the relative strengths of above‐ and below‐ground competition from lianas on tree saplings in a disturbed forest in Côte d’Ivoire with a heterogeneous canopy and relatively high light penetration. We planted seedlings of three tree species and subjected them …

Guest Editorial: The Pastoral Care Of The Physician, Greg F. Burke

The Linacre Quarterly

No abstract provided.

The Brave New World Of Embryonic Stem Cell Research: Utilitarian Consequentialism And Faulty Moral Reasoning, John R. Meyer

The Linacre Quarterly

No abstract provided.

Democracy And Abortion, Monte Harris Liebman

The Linacre Quarterly

No abstract provided.

Is The Human Zygote A Person?, Thomas Nelson

The Linacre Quarterly

No abstract provided.

Stem Cell Research, Cloning And Catholic Moral Theology, Ronald Fabbro

The Linacre Quarterly

No abstract provided.

The Plague Of Terrorism, Peter J. Riga

The Linacre Quarterly

No abstract provided.

Balancing Two Vocations: Marriage And Medicine In A Culture Of Life, Kevin Murrell, Karen Murrell

The Linacre Quarterly

No abstract provided.

Reflections On Conception, Theodore Gillian

The Linacre Quarterly

No abstract provided.

Toward A Theory Of The Autonomous Family, Allan Carlson

The Linacre Quarterly

No abstract provided.

The Sleeping Giant, Eugene F. Diamond

The Linacre Quarterly

No abstract provided.

Spectroscopic And Thermodynamic Characterization Of The E151d And E151a Altered Leucine Aminopeptidases From Aeromonas Proteolytica, Krzysztof P. Bzymek, Sabina I. Swierczek, Brian Bennett, Richard C. Holz

Physics Faculty Research and Publications

Previous kinetic characterization of the glutamate 151 (E151)-substituted forms of the leucine aminopeptidase from Aeromonas proteolytica (Vibrio proteolyticus; AAP) has provided critical evidence that this residue functions as the general acid/base. The close proximity of similar glutamate residues to the bridging water/hydroxide of the dinuclear active sites of metalloenzymes (2.80 and 3.94 Å in carboxypeptidase G₂ and 3.30 and 3.63 Å in AAP), suggests it may also be involved in stabilizing the active-site metal ions. Therefore, the structural perturbations of the dinuclear active site of AAP were examined for two E151-substituted forms, namely E151D-AAP and E151A-AAP, by …

Spatially Disjunct Effects Of Co‐Occurring Competition And Facilitation, Ian A. Dickie

Biological Sciences Faculty Research and Publications

Little is known of the co‐occurrence and implications of competitive and facilitative interactions within sites. Here we show spatially disjunct competition and facilitation at forest edges, with beneficial influences of trees on seedling growth via increased ectomycorrhizal infection apparent from 12 to 20 m while closer to trees seedling growth is negatively correlated with canopy closure. As a result, seedling growth is maximized at intermediate distances. Facilitative interactions were nonlinear: being within 15.7 m of a tree maximized seedling mycorrhizal infection; while competitive effects were correlated with canopy closure, which was related to distance and generally scales with density. These …

A Systematic Review Of Mammography Educational Interventions For Low-Income Women, Tatiana Bailey, Jorge Delva, Kimberlee A. Gretebeck, Kristine Siefert, Amid I. Ismail

College of Nursing Faculty Research and Publications

Objective

We conducted a systematic review to examine the effectiveness of educational interventions in increasing mammography screening among low-income women.

Data Sources

Bibliographic databases, including MEDLINE, The Cochrane Central Register of Controlled Trials, The Cochrane Database of Systematic Reviews, and the ISI Web of Science, were searched for relevant articles.

Study Inclusion and Exclusion Criteria

Randomized, community-based trials targeting low-income women and published between January 1980 and March 2003 were included.

Data Extraction

The search yielded 242 studies; 24 met all inclusion criteria.

Data Synthesis

Three studies used mammography vans, three used low-cost vouchers or provided free mammograms, three used …

Wound Debridement With 25 Khz Ultrasound, Margaret Mccarty Stanisic, Barbara Provo, David L. Larson, Luther C. Kloth

Physical Therapy Faculty Research and Publications

Several methods of wound debridement are described in the literature and are available to health care providers who specialize in wound management. Methods include the use of sharp surgical instruments; mechanical methods, such as whirlpool and pulsed lavage with suction; proteolytic and collagenolytic enzymes; autolysis; and sterile fly larvae (maggots). The use of surgical debridement is generally considered the most efficient method when performed by a skilled physician, who may in one session use his or her discretion to excise some viable tissue along with necrotic tissue in the wound. Sharp debridement performed in a clinical setting is a less …