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Mechanism Of Mechanical Vibration In Enhancing Orthodontic Retention- Analysis Of Global Gene Expression, Shuwei Wang
Mechanism Of Mechanical Vibration In Enhancing Orthodontic Retention- Analysis Of Global Gene Expression, Shuwei Wang
Master's Theses (2009 -)
Introduction: Low-magnitude, high-frequency (LMHF) mechanical vibration has been proposed as a possible adjunctive retention method after orthodontic treatment. In this study, we explored the mechanism of using LMHF vibration to improve bone formation during retention phase. We aimed to provide insight of global gene expression and cellular activities of PDL cells under tension, as well as identify novel biomarkers for induced osteogenesis by using LMHF mechanical vibration as adjunct tool in retention phase. Materials and Methods: Human PDL cells (hPDLCs) were seeded in 6-well FLEXCELL culture plates. The wells were assigned to four experimental groups as control, stretching (ST), vibration …