Digital Commons Network^™

Development And Implementation Of High-Throughput Snpgenotyping In Barley, Serdar Bozdag, Timothy J. Close, Prasanna R. Bhat, Stefano Lonardi, Yonghui Wu, Nils Rostoks, Luke Ramsay, Arnis Druka, Nils Stein, Jan T. Svensson, Steve Wanamaker, Mikeal L. Roose, Matthew J. Moscou, Shiaoman Chao, Rajeev K. Varshney, Peter Szucs, Kazuhiro Sato, Patrick M. Hayes, David E. Matthews, Andris Kleinhofs, Gary J. Muehlbauer, Joseph Deyoung, David F. Marshall, Kavitha Madishetty, Raymond D. Fenton, Pascal Condamine, Andreas Graner, Robbie Waugh

Mathematics, Statistics and Computer Science Faculty Research and Publications

Background

High density genetic maps of plants have, nearly without exception, made use of marker datasets containing missing or questionable genotype calls derived from a variety of genic and non-genic or anonymous markers, and been presented as a single linear order of genetic loci for each linkage group. The consequences of missing or erroneous data include falsely separated markers, expansion of cM distances and incorrect marker order. These imperfections are amplified in consensus maps and problematic when fine resolution is critical including comparative genome analyses and map-based cloning. Here we provide a new paradigm, a high-density consensus genetic map of …

Isolation And X-Ray Structural Characterization Of A Dicationic Homotrimer Of 2,3,6,7-Tetramethoxy-9,10-Dimethylanthracene Cation Radical, Matthew J. Modjewski, Ruchi Shukla, Sergey Lindeman, Rajendra Rathore

Chemistry Faculty Research and Publications

Electrochemical oxidation of 2,3,6,7-tetramethoxy-9,10-dimethylanthracene (1) showed that it undergoes a highly reversible electrochemical oxidation (E_ox = 0.81 V vs SCE) and forms a modestly stable cation-radical salt in solution. X-ray crystallography established that 1⁺SbCl₆^- crystallizes as a (centrosymmetric) dicationic homotrimer via a close cofacial association of a pair of cationic and one neutral molecule of 1 with an interplanar separation of ∼3.2 Å. The structure of the dicationic homotrimer was also reproduced by DFT calculations. Furthermore, the structure of a dicationic spiro adduct, formed by a slow decomposition of a solution of 1^{+ …}

The Incidence Of Tobacco Taxation: Evidence From Geographic Micro-Level Data, Andrew Hanson, Ryan Sullivan

Economics Faculty Research and Publications

This paper uses a recent increase in Wisconsin’s tobacco tax as a natural experiment to measure the economic incidence of tobacco taxation, using micro-level data on cigarette prices from retail locations in Wisconsin and states that share its border. We find that Wisconsin’s $1 tobacco tax increase was over-shifted to consumers; they pay the entire amount of the tax as well as a premium of between 8–17 cents per pack of cigarettes. We also use geo-coded data to test if the incidence of the tobacco tax is different for locations near the border of states with different tobacco taxation.

The Capabilities Conception Of The Individual, John B. Davis

Economics Faculty Research and Publications

This paper advances a capabilities conception of the individual, and considers some of the problems involved in developing such a conception. It also makes claims about the nature of the capability space as a whole, frames personal development in terms of the idea of moving though the capability space, and argues that people are alike in being increasingly heterogeneous. A key problem for a capabilities conception of the individual is that some capabilities, such as belonging to social groups and having social identities, can undermine individuality. The paper discusses an example in which people can have social identities but can …

Identity And Democracy: Linking Individual And Social Reasoning, John B. Davis, Solange Regina Marin

Economics Faculty Research and Publications

Following Amartya Sen's approach, John Davis and Solange Regina Marin look at individual and social reasoning when examining the complex relationship between identity and democracy. They characterize democracy as a process of social or public reasoning that combines the individual reasoning of all citizens. Identity is explained in terms of personal identity, social identity, and individual identity. They argue that democracy in combining the individual reasoning of all citizens responds to individuals’ different personal identity concerns and needs, reflects their shared social identity interests and goals, and accords them rights and responsibilities associated with their many different individual identities.

The Roles Of Physical Therapists In Wound Management: Part Iv, Luther C. Kloth

Physical Therapy Faculty Research and Publications

Physical therapists are important members of the comprehensive wound management team. In addition to being able to provide standard wound care, they are well prepared to treat wounds with a variety of biophysical agents that introduce electromagnetic, acoustic, and mechanical energies that enhance healing. Physical therapists also address restoration of function that is frequently compromised in patients who suffer from chronically and acutely wounded tissues.

Reactivity Of Phenyldi(2-Thienyl)Phosphine Towards Group 7 Metal Carbonyls: Carbon–Phosphorus Bond Activation, Shishir Ghosh, Alok K. Das, Noorjahan Begum, Daniel T. Haworth, Sergey Lindeman, James R. Gardinier, Tasneem A. Siddiquee, Dennis W. Bennett, Ebbe Nordlander, Graeme Hogarth, Shariff E. Kabir

Chemistry Faculty Research and Publications

Addition of phenyldi(2-thienyl)phosphine (PPhTh₂) to [Re₂(CO)_10−n(NCMe)_n] (n = 1, 2) affords the substitution products [Re₂(CO)_10−n(PhPTh₂)_n] (1, 2) together with small amounts of fac-[ClRe(CO)₃(PPhTh₂)₂] (3) (n = 2). Reaction of [Re₂(CO)₁₀] with PPhTh₂in refluxing xylene affords a mixture which includes 2, [Re₂(CO)₇(PPhTh₂)(μ-PPhTh)(μ-H)] (4), [Re₂(CO)₇(PPhTh₂)(μ-PPhTh)(μ-η¹,κ¹(S)-C₄H₃S)] (5) and …

The Professional Portfolio: An Evidence-Based Assessment Method, Michelle Byrne, Kathryn Schroeter, Shannon Carter, Julie Mower

College of Nursing Faculty Research and Publications

Competency assessment is critical for a myriad of disciplines, including medicine, law, education, and nursing. Many nurse managers and educators are responsible for nursing competency assessment, and assessment results are often used for annual reviews, promotions, and satisfying accrediting agencies' requirements. Credentialing bodies continually seek methods to measure and document the continuing competence of licensees or certificants. Many methods and frameworks for continued competency assessment exist. The portfolio process is one method to validate personal and professional accomplishments in an interactive, multidimensional manner. This article illustrates how portfolios can be used to assess competence. One specialty nursing certification board's process …

Effects On Resilience Of Women Family Caregivers Of Adults With Serious Mental Illness: The Role Of Positive Cognitions, Jaclene A. Zauszniewski, Abir K. Bekhet, M. Jane Suresky

College of Nursing Faculty Research and Publications

This study examined the effects of risk and protective factors on resilience in 60 women family members of adults with serious mental illness. Both the risk factors constituting caregiver burden (strain, stigma, client dependence, and family disruption) and protective factors, including eight positive cognitions were found to predict two indicators of resilience: resourcefulness and sense of coherence. The effects of caregiver burden on resourcefulness and sense of coherence were mediated by positive cognitions, lending support to resilience theory and suggesting the need to develop interventions to encourage positive thinking among women caregivers of adults with mental illness.

Dental Treatment Under General Anesthesia In Healthy And Medically Compromised/Developmentally Disabled Children: A Comparative Study, Juan Pablo Loyola-Rodriguez, Veronica Zavala-Alonso, Cinthya L. Gonzalez-Alvarez, Lilia A. Juarez-Lopez, Nuria Patiño-Marin, Cesar D. Gonzalez

School of Dentistry Faculty Research and Publications

Aim: To compare the type, number of procedures and working time of dental treatment provided under dental general anesthesia (DGA) in healthy and medically compromised/developmentally disabled children (MCDD children). Design: This cross-sectional prospective study involved 80 children divided into two groups of 40 children each. Group 1 consisted of healthy and Group 2 consisted of MCDD children. Results: Healthy children needed more working time than MCDD children, the means being 161±7.9 and 84±5.7 minutes, respectively (P= 0.0001). Operative dentistry and endodontic treatments showed a significant statistical difference (P= 0.0001). The means of procedures were 17±5.0 for healthy children and 11±4.8 …

Pulp Polyp Associated With A Natal Tooth: Case Report, Brian D. Hodgson, Rodney Vergotine, Lance Lambert

School of Dentistry Faculty Research and Publications

Natal teeth are an infrequent occurrence at birth. Often these teeth are extracted because they are very mobile and pose a risk of aspiration. This is a rare case in which a natal tooth was extracted by the pediatrician with his fingers. A root fragment remained and out of this developed a large pulp polyp. This relationship has not been previously reported.

Catholic Institutions Of Higher Education And K-12 Schools Partnering For Social Justice: A Call For Scholarship, Joan Whipp, Martin Scanlan

College of Education Faculty Research and Publications

This article calls for scholarship on emerging partnerships between Catholic institutions of higher education and Catholic K-12 schools that aim at socially just schooling. Justice, ethical care, learning, and social entrepreneurship are explored as possible conceptual frameworks for this research.

Race, Power, And (In)Equity Within Two-Way Immersion Settings, Martin Scanlan, Deborah Palmer

College of Education Faculty Research and Publications

Two-way immersion schools provide a promising model for service delivery to students who are English language learners. With the goals of bilingualism, academic excellence, and cross cultural appreciation, these schools are designed to build bridges across linguistically heterogeneous student bodies. Yet while empirical evidence demonstrates that the two-way immersion model can be effective in these regards, we know little about how such schools address other dimensions of diversity, including race, ethnicity, class, and disability. This study contributes to filling this gap by critically analyzing these dimensions in the areas of recruitment and retention in two two-way immersion schools.

Isoform- And Cell-Specific Function Of Tyrosine Decarboxylase In The Drosophila Malpighian Tubule, Edward M. Blumenthal

Biological Sciences Faculty Research and Publications

The biogenic amine tyramine (TA) is a potent diuretic factor when applied to the Malpighian tubule (MT) of Drosophila melanogaster, stimulating both urine production and transepithelial chloride conductance. Isolated MTs can respond not only to TA but also to its precursor, tyrosine; this observation led to the proposal that MTs are able to synthesize TA from applied tyrosine through the action of the enzyme tyrosine decarboxylase (TDC). In the current study it is shown that the non-neuronal isoform of TDC, Tdc1, is expressed in the principal cells of the MT. A mutant allele of Tdc1, Tdc1^{f03311 …}

Family Businesses Must Be Run More ‘Professionally’, Alex Stewart

Management Faculty Research and Publications

No abstract provided.

Inhibitors Of Bacterial N-Succinyl-L,L-Diaminopimelic Acid Desuccinylase (Dape) And Demonstration Of In Vitro Antimicrobial Activity, Danuta Gillner, Nicola Armoush, Richard C. Holz, Daniel P. Becker

Chemistry Faculty Research and Publications

The dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) is a critical bacterial enzyme for the construction of the bacterial cell wall. A screen biased toward compounds containing zinc-binding groups (ZBG’s) including thiols, carboxylic acids, boronic acids, phosphonates and hydroxamates has delivered a number of micromolar inhibitors of DapE from Haemophilus influenzae, including the low micromolar inhibitor L-captopril (IC₅₀ = 3.3 μM, K_i = 1.8 μM). In vitro antimicrobial activity was demonstrated for l-captopril against Escherichia coli.

A Framework For Bioacoustic Vocalization Analysis Using Hidden Markov Models, Yao Ren, Michael T. Johnson, Patrick J. Clemins, Michael Darre, Sharon Stuart Glaeser, Tomasz S. Osiejuk, Ebenezer Out-Nyarko

Electrical and Computer Engineering Faculty Research and Publications

Using Hidden Markov Models (HMMs) as a recognition framework for automatic classification of animal vocalizations has a number of benefits, including the ability to handle duration variability through nonlinear time alignment, the ability to incorporate complex language or recognition constraints, and easy extendibility to continuous recognition and detection domains. In this work, we apply HMMs to several different species and bioacoustic tasks using generalized spectral features that can be easily adjusted across species and HMM network topologies suited to each task. This experimental work includes a simple call type classification task using one HMM per vocalization for repertoire analysis of …

Μ-Opioid Receptor Agonist Injections Into The Presumed Pre-Bötzinger Complex And The Surrounding Region Of Awake Goats Do Not Alter Eupneic Breathing, K. L. Krause, Suzanne E. Neumueller, B. D. Marshall, T. Kiner, Joshua M. Bonis, Lawrence Pan, B. Qian, Hubert V. Forster

Physical Therapy Faculty Research and Publications

Opioids are clinically important in the alleviation of pain. An undesirable side effect of opioids is depression of breathing. Data from isolated preparations suggest this effect is due to attenuation of discharge activity of neurons in the pre-Bötzinger complex (preBötzC), a medullary area with respiratory rhythmogenic properties. The purpose of this study was to examine how [d-Ala(2),N-Me-Phe(4),Gly(5)-ol]-enkephalin (DAMGO), a μ-opioid receptor agonist, affected breathing after injection into the presumed preBötzC of the adult awake goat. We hypothesized that DAMGO would cause breathing to decrease and become irregular when injected into the presumed preBötzC and the surrounding region of the conscious …

Analysis And Diagnostics Of Adjacent And Nonadjacent Broken-Rotor-Bar Faults In Squirrel-Cage Induction Machines, Gennadi Y. Sizov, Ahmed Mohamed Sayed Ahmed, Chia-Chou Yeh, Nabeel Demerdash

Electrical and Computer Engineering Faculty Research and Publications

In this paper, faults associated with the rotor of an induction machine are considered. More specifically, effects of adjacent and nonadjacent bar breakages on rotor fault diagnostics in squirrel-cage induction machines are studied. It is shown that some nonadjacent bar breakages may result in the masking of the commonly used fault indices and, hence, may lead to a possible misdiagnosis of the machine. A discussion of the possible scenarios of these breakages as well as some conclusions regarding the types of squirrel-cage induction machines (number of poles, number of squirrel-cage bars, etc.) that may be more prone to these nonadjacent …

Demonstration Of A Bias Tunable Quantum Dots-In-A-Well Focal Plane Array, Jonathan Andrews, Woo-Yong Jang, Jorge E. Pezoa, Yagya D. Sharma, Sang Jun Lee, Sam Kyu Noh, Majeed M. Hayat, Sergio Restaino, Scott W. Teare, Sanjay Krishna

Electrical and Computer Engineering Faculty Research and Publications

Infrared detectors based on quantum wells and quantum dots have attracted a lot of attention in the past few years. Our previous research has reported on the development of the first generation of quantum dots-in-a-well (DWELL) focal plane arrays, which are based on InAs quantum dots embedded in an InGaAs well having GaAs barriers. This focal plane array has successfully generated a two-color imagery in the mid-wave infrared (i.e. 3–5 μm) and the long-wave infrared (i.e. 8–12 μm) at a fixed bias voltage. Recently, the DWELL device has been further modified by embedding InAs quantum dots in InGaAs …

Influx Of Calcium Through L-Type Calcium Channels In Early Postnatal Regulation Of Chloride Transporters In The Rat Hippocampus, Jennifer Grace Bray, Michelle Mynlieff

Biological Sciences Faculty Research and Publications

During the early postnatal period, GABA_B receptor activation facilitates L-type calcium current in rat hippocampus. One developmental process that L-type current may regulate is the change in expression of the K⁺Cl⁻ co-transporter (KCC2) and N⁺K⁺2Cl⁻ co-transporter (NKCC1), which are involved in the maturation of the GABAergic system. The present study investigated the connection between L-type current, GABA_B receptors, and expression of chloride transporters during development. The facilitation of L-type current by GABA_B receptors is more prominent in the second week of development, with the highest percentage of cells exhibiting …

Latino Definitions Of Success: A Cultural Model Of Intercultural Competence, Lucas Torres

Psychology Faculty Research and Publications

The present study sought to examine Latino intercultural competence via two separate methodologies. Phase 1 entailed discovering and generating themes regarding the features of intercultural competence based on semistructured interviews of 15 Latino adults. Phase 2 included conducting a cultural consensus analysis from the quantitative responses of 46 Latino adults to determine the cultural model of intercultural competence. The major results indicated that the participants, despite variations in socioeconomic and generational statuses, shared a common knowledge base regarding the competencies needed for Latinos to successfully navigate different cultures. Overall, the cultural model of Latino intercultural competence includes a set of …

Locating Decision Rights: Evidence From The Mutual Fund Industry, George D. Cashman, Daniel N. Deli

Finance Faculty Research and Publications

Mutual fund advisors make portfolio decisions for their funds on a daily basis. We examine the location of these portfolio decision rights on two dimensions. First, we consider the geographic location of the decision rights. Second, we consider whether the decision rights remain with an advisor or are allocated to an independent sub-advisor. We argue that the allocation of portfolio decision rights involves a tradeoff between the opportunity cost of not matching decision rights with specific knowledge, and the agency costs associated with moving the decision rights to the specific knowledge. The patterns in the location of decision rights are …

Learning From The Past And Looking To The Future: A Conversation Between Pamela Tate And Robert Deahl About The Past 35 Years In Adult Learning, Pamela Tate, Robert Deahl, Rebecca Klein-Collins

College of Professional Studies Faculty Research and Publications

None Provided

Comparison Of Cumulative Planimetry Versus Manual Dissection To Assess Experimental Infarct Size In Isolated Hearts, Matthias L. Riess, Samhita S. Rhodes, David F. Stowe, Mohammed Aldakkak, Amadou K.S. Camara

Biomedical Engineering Faculty Research and Publications

Introduction

Infarct size (IS) is an important variable to estimate cardiac ischemia/reperfusion injury in animal models. Triphenyltetrazolium chloride (TTC) stains viable cells red while leaving infarcted cells unstained. To quantify IS, infarcted and non-infarcted tissue is often manually dissected and weighed (IS-DW). An alternative is to measure infarcted areas by cumulative planimetry (IS-CP).

Methods

We prospectively compared these two methods in 141 Langendorff-prepared guinea pig hearts (1.44 ± 0.02 g) that were part of different studies on mechanisms of cardioprotection. Hearts were perfused with Krebs–Ringer's and subjected to 30 min global ischemia after various cardioprotective treatments. Two hours after reperfusion …

Exploiting Multiple Sensory Modalities In Brain-Machine Interfaces, Aaron J. Suminski, Dennis C. Tkach, Nicholas G. Hatsopoulos

Biomedical Engineering Faculty Research and Publications

Recent improvements in cortically-controlled brain-machine interfaces (BMIs) have raised hopes that such technologies may improve the quality of life of severely motor-disabled patients. However, current generation BMIs do not perform up to their potential due to the neglect of the full range of sensory feedback in their strategies for training and control. Here we confirm that neurons in the primary motor cortex (MI) encode sensory information and demonstrate a significant heterogeneity in their responses with respect to the type of sensory modality available to the subject about a reaching task. We further show using mutual information and directional tuning analyses …

Polymer Nanocomposites Using Zinc Aluminum And Magnesium Aluminum Oleate Layered Double Hydroxides: Effects Of The Polymeric Compatibilizer And Of Composition On The Thermal And Fire Properties Of Pp/Ldh Nanocomposites, Charles Manzi-Nshuti, Ponusa Songtipya, Evangelos Manias, Maria Del Mar Jimenez-Gasco, Jeanne Hossenlopp, Charles A. Wilkie

Chemistry Faculty Research and Publications

A series of five oleate-containing layered double hydroxides with varied ratios of zinc to magnesium, i.e., with the general formula Zn_2−yMg_yAl(OH)₆ [CH₃(CH₂)₇CHCH(CH₂)₇COO]·nH₂O, were synthesized and used to prepare nanocomposites of polypropylene (PP). The nanomaterials were characterized by elemental analysis, attenuated total reflection-infrared spectroscopy (ATR-IR), X-ray diffraction (XRD) and thermogravimetric analysis (TGA), while the composites were characterized by XRD, TGA, transmission electron microscopy (TEM) and cone calorimetry. The zinc-containing LDH showed better dispersion in the polymer at the micrometer level …

The Effects Of Intralayer Metal Composition Of Layered Double Hydroxides On Glass Transition, Dispersion, Thermal And Fire Properties Of Their Pmma Nanocomposites, Charles Manzi-Nshuti, Dan Chen, Shengpei Su, Charles A. Wilkie

Chemistry Faculty Research and Publications

A series of aluminum-containing layered double hydroxides (LDHs), containing Mg, Ca, Co, Ni, Cu and Zn as the divalent metals, have been prepared by the co-precipitation method and used to prepare nanocomposites of PMMA by in situ bulk polymerization. The additives were characterized by Fourier transform infrared spectroscopy, X-ray diffraction spectroscopy (XRD) and thermogravimetric analysis while the polymer composites were characterized by XRD, transmission electron microscopy, differential scanning calorimetry and cone calorimetry. Polymerization of methyl methacrylate in the presence of these undecenoate LDHs results in composites with enhanced thermal stability. The glass transition temperatures of the composites and the pristine …

How To Select The Correct Education Strategy: When Not To Go Online, Carol Klingbeil, Norah L. Johnson, Joan P. Totka, Lynn Doyle

College of Nursing Faculty Research and Publications

Screening for intimate partner violence is an important injury prevention strategy. Nurses who develop staff education, to promote screening, need to select a method that is sensitive to learners. Online learning, although convenient, is not well suited to sensitive topics such as screening for intimate partner violence. The purpose of this article is to describe a curriculum for intimate partner violence screening based on self-efficacy theory, which includes a hospital-produced video, a role play, and a discussion.

Organizational Learning From Extreme Performance Experience: The Impact Of Success And Recovery Experience, June-Young Kim, Ji-Yub Kim, Anne S. Miner

Management Faculty Research and Publications

This paper argues that two different types of a firm’s own extreme performance experiences—success and recovery—and their interactions can generate survival-enhancing learning. Although these types of experience often represent valuable sources of useful learning, several important learning challenges arise when a firm has extremely limited prior experience of the same type. Thus, we theorize that a certain threshold of a given type of experience is required before each type of experience becomes valuable, with low levels of experience harming the organization. Furthermore, we propose that success and recovery experience will interact to enhance each other’s value. These conditions can help …