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Psychology Faculty Research and Publications
Working memory; Prefrontal cortex; Delayed response task; fMRI
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Evidence For Multiple Manipulation Processes In Prefrontal Cortex, Dana A. Eldreth, Michael D. Patterson, Anthony J. Porcelli, Bharat B. Biswal, Donovan Rebbechi, Bart Rypma
Evidence For Multiple Manipulation Processes In Prefrontal Cortex, Dana A. Eldreth, Michael D. Patterson, Anthony J. Porcelli, Bharat B. Biswal, Donovan Rebbechi, Bart Rypma
Psychology Faculty Research and Publications
The prefrontal cortex (PFC) is known to subserve working memory (WM) processes. Brain imaging studies of WM using delayed response tasks (DRTs) have shown memory-load-dependent activation increases in dorsal prefrontal cortex (PFC) regions. These activation increases are believed to reflect manipulation of to-be-remembered information in the service of memory-consolidation. This speculation has been based on observations of similar activation increases in tasks that overtly require manipulation by instructing participants to reorder to-be-remembered list items. In this study, we tested the assumption of functional equivalence between these two types of WM tasks. Participants performed a DRT under two conditions with memory …