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Plastic And Evolved Responses To Global Change: What Can We Learn From Comparative Transcriptomics?, Melissa B. Debiasse, Morgan W. Kelly
Plastic And Evolved Responses To Global Change: What Can We Learn From Comparative Transcriptomics?, Melissa B. Debiasse, Morgan W. Kelly
Faculty Publications
© The American Genetic Association. 2015. All rights reserved. Physiological plasticity and adaptive evolution may facilitate persistence in a changing environment. As a result, there is an interest in understanding species' capacities for plastic and evolved responses, and the mechanisms by which these responses occur. Transcriptome sequencing has become a powerful tool for addressing these questions, providing insight into otherwise unobserved effects of changing conditions on organismal physiology and variation in these effects among individuals and populations. Here, we review recent studies using comparative transcriptomics to understand plastic and evolutionary responses to changing environments. We focus on 2 areas where …
Studies On Development Of End Rot In Sweetpotato, Ratchanee Pattaravayo
Studies On Development Of End Rot In Sweetpotato, Ratchanee Pattaravayo
LSU Doctoral Dissertations
End rot development in sweetpotato is caused by several pathogens and exacerbated by unfavorable environments. A critical need exists to know what factors in the environment trigger end rot development and how to manage the crop to minimize the incidence of end rots which are the overall objectives of this study. This research was divided into three studies: 1) Effect of environmental factors on expression of end rot in sweetpotato roots. Factorial combinations consisted of flooding/non-flooding; skinned/non-skinned; cured/non-cured; recommended storage/ambient storage are environmental variables not tested previously together in a systematic way. Results showed that curing at 29oC and 85-90% …
Extraction And Biochemical Characterization Of Alligator Mississippiensis Glycosaminoglycans And An Ex-Vivo Murine Pilot Study To Test Their Potential Effect On A Selected Panel Of Genes Associated With Cystic Fibrosis, Jose Daniel Estrada Andino
Extraction And Biochemical Characterization Of Alligator Mississippiensis Glycosaminoglycans And An Ex-Vivo Murine Pilot Study To Test Their Potential Effect On A Selected Panel Of Genes Associated With Cystic Fibrosis, Jose Daniel Estrada Andino
LSU Doctoral Dissertations
Cystic fibrosis (CF) is a genetic disorder with a median survival age of 40.7 years. Chronic airway inflammation and dehydration are critical features of CF. The size and structure-dependent hydration and anti-inflammatory properties of glycosaminoglycans (GAGs) such as hyaluronic acid (HA) may help ameliorate these symptoms. The GAGs contained in farmed Alligator mississippiensis by-products offer a potential to improve waste management practices and increase revenue in the alligator industry, through their development for use in biomedical applications. This study aimed to efficiently extract and characterize GAGs from alligator carcasses (ACS), backstraps (ABS), feet (AFT) and eyeballs (AEB), to evaluate their …
Role Of An Adenylyl Cyclase Isoform In Alcohol's Effect On Cyclic Amp Regulated Gene Expression In Mammalian Cells, Rebecca Ann Hill
Role Of An Adenylyl Cyclase Isoform In Alcohol's Effect On Cyclic Amp Regulated Gene Expression In Mammalian Cells, Rebecca Ann Hill
LSU Doctoral Dissertations
Research suggests that the cyclic AMP (cAMP) signaling pathway including CREB-CRE regulated expression of various genes is implicated in the predisposition to and development of alcoholism in humans. Alcohol also induces changes in inflammatory and immune responses; these changes increase the incidence of pneumonias and other infections, which can negatively affect recovery from infections. Cyclic AMP (cAMP) is known for its immunosuppressive effects and is also required for proper development of the immune system. Previous work in our laboratory has demonstrated that ethanol enhances the activity of adenylyl cyclase (AC) in an isoform-specific manner; type 7 AC (AC7) is most …