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A Spatial Inquiry Of Infant Low Birthweight And Cancer Mortality In East Baton Rouge Parish, Louisiana., Esra Ozdenerol
A Spatial Inquiry Of Infant Low Birthweight And Cancer Mortality In East Baton Rouge Parish, Louisiana., Esra Ozdenerol
LSU Historical Dissertations and Theses
Infant low birthweight rate in East Baton Rouge Parish is higher compared to the nation. Cancer is one of the most serious health problems in Louisiana. A few studies have indicated a relationship between the two health outcomes and their environment, but conclusions from these studies have not always been consistent. The spatial and temporal scales of the data and the methods used in these studies contribute to the inconsistent and uncertain results. The spatial patterns of infant low birthweight and cancer mortality in East Baton Rouge Parish from 1993 to 1996 and their relationships with environmental factors at three …
Effects Of Dietary L -Carnitine On Female Retired Breeder Rats Fed High Protein And High Fat., Erika Maria Zablah-Bendeck
Effects Of Dietary L -Carnitine On Female Retired Breeder Rats Fed High Protein And High Fat., Erika Maria Zablah-Bendeck
LSU Historical Dissertations and Theses
Carnitine supplementation has been shown to protect animals from ammonia toxicity following an ammonium acetate infusion and to alter body composition (i.e. increase lean mass and decrease body fat) in younger animals. The aims of this study were to address the questions of whether: (1) carnitine lowers blood ammonia levels of rats fed high protein; (2) carnitine decreases the weight gain and body fat of older animals fed high fat; (3) carnitine decreases glucose-induced insulin secretion; and (4) consumption of a high fat diet increases total serum carnitine content. Sprague Dawley retired female breeder rats (n = 64) were stratified …
Professional Versus Caregiver Ratings Of The Communicative Abilities Of Adults Displaying Moderate To Profound Communication Challenges., Paul Steven Miller
Professional Versus Caregiver Ratings Of The Communicative Abilities Of Adults Displaying Moderate To Profound Communication Challenges., Paul Steven Miller
LSU Historical Dissertations and Theses
Ninety caregivers of 30 adults with moderate-to-serve cognitive, sensory, and physical challenges living in an institutional setting participated in this study to investigate caregiver perceptions of communicative abilities. A mixed effects design was used to compare communication scores of thirty adults. The adults were assigned to three communication proficiency groups. The communicative scores with challenges that were generated with three different assessment activities: a direct/participatory evaluation conducted by a certified speech-language pathologist, an interview of the caregivers, and an observation of daily routine activities. Results indicated that all of the rating procedures differentiated the three communication proficiency groups. Correlations between …
Intestinal Bioavailability And Biotransformation Of 3,4,3',4'-Tetrachlorobiphenyl In The Channel Catfish, Ictalurus Punctatus., Adriana Maria Doi
Intestinal Bioavailability And Biotransformation Of 3,4,3',4'-Tetrachlorobiphenyl In The Channel Catfish, Ictalurus Punctatus., Adriana Maria Doi
LSU Historical Dissertations and Theses
These studies examined the role of micelle fatty acid composition, contaminant body burden, biotransformation, and non-specific toxicity on the systemic bioavailability of 3,4,3',4'-tetrachlorobiphenyl (TCB) from the intestine of catfish, as well as the effect of TCB upon the vectorial transporter p-glycoprotein (pgp). Initial in vitro experiments demonstrated that the solubility of [14C]-TCB in micelles was favored by longer chain fatty acids, with higher [14C]-TCB solubility correlating to greater systemic bioavailability of [14C]-TCB in an in situ preparation. The systemic bioavailability of [14C]-TCB was demonstrated to be affected by in vivo exposures to TCB, in a dose-independent manner, and apparently unrelated …
Indices Of Exposure To Polycyclic Aromatic Hydrocarbons In A Bioindicator Species: Point Mutation Detection In The Cotton Rat., Christine H. Lemarchand-Carpentier
Indices Of Exposure To Polycyclic Aromatic Hydrocarbons In A Bioindicator Species: Point Mutation Detection In The Cotton Rat., Christine H. Lemarchand-Carpentier
LSU Historical Dissertations and Theses
Release of energy-related contaminants occurs ubiquitously in the environment. Cancer induction by polycyclic aromatic hydrocarbons (PAHs) and aromatic amines have been well recognized in the workplace and are also suspected among the general population. Environmental PAHs exposure and effects have been investigated using biomarkers in aquatic and, to a lesser extent, terrestrial animals. Attempts to monitor the presence and effects of PAHs through the detection of point mutations in genes involved in carcinogenesis (p53 and K-ras) would yield interesting clues regarding possible etiologic agents and their potential effect. The identification of a mutation type, known to be G→T transversion predominantly …
The Effects And Mechanism Of Action Of Cimetidine On Inducible Nitric Oxide Synthase Using An Equine Soft-Tissue Inflammation Model., Robert Paul Hunter
The Effects And Mechanism Of Action Of Cimetidine On Inducible Nitric Oxide Synthase Using An Equine Soft-Tissue Inflammation Model., Robert Paul Hunter
LSU Historical Dissertations and Theses
Cytochrome P-450 (CYP) and inducible nitric oxide synthase (iNOS) are similar heme containing enzymes. Cimetidine (CIM) is an H2 antagonist, and since CIM inhibits CYP, it may also bind to the heme-iron of NOS and reduce NO generation. Six horses each had three tissue chambers inserted subcutaneously on either side of the neck for Trial 1. Trial 2 also used 6 female Thoroughbred horses implanted with at least two tissue chambers as in Trial 1. Blood and tissue chamber fluid (TCF) were sampled at -24, 0, 4, 8, 12 h and at 1, 2, 3, 5, and 7 days after …