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Investigating The Role Of Integrin Beta 3 In Dendritic Arborization In The Supragranular Developing Cerebral Cortex, Zachary Logan Holley May 2019

Investigating The Role Of Integrin Beta 3 In Dendritic Arborization In The Supragranular Developing Cerebral Cortex, Zachary Logan Holley

Senior Honors Projects, 2010-2019

Integrin subunits have been implicated in axonal and dendritic outgrowth. In particular, a strong positive association has been found between mutations in integrin beta 3 (Itgb3) and autism spectrum disorder, but little is known about neuronal Itgb3 function in vivo. Many forms of autism spectrum disorder are thought to arise from dysfunctional dendritic arborization and synaptic pruning. Global knockout of Itgb3 in mice leads to autistic-like behaviors. Itgb3-/- mice also have reduced callosal volume, a key neuroanatomical correlate of autism. Here, we test the hypothesis that Itgb3 is required for normal dendritic arborization in layer II/III pyramidal …


An Exploration Of The Rapid Prompting Method For Students With Autism, Shea Manship May 2018

An Exploration Of The Rapid Prompting Method For Students With Autism, Shea Manship

Senior Honors Projects, 2010-2019

The Rapid Prompting Method (RPM) was created by Soma Mukhopadhyay as an attempt to provide a way for individuals with autism to learn and communicate. The method has been said to give students with autism a means of communication. A facilitator quickly provides verbal prompts to the individual, who then spells out messages on a letter board or a keyboard. Very little research has been done on RPM, and it is not considered an evidence-based method. Many professionals believe that RPM is not a valid method of communication, largely due to the striking similarities it has with Facilitated Communication (FC). …


Interdisciplinary Skill Development During Summer Autism Clinic, Rachel F. Kagle May 2017

Interdisciplinary Skill Development During Summer Autism Clinic, Rachel F. Kagle

Senior Honors Projects, 2010-2019

The present paper focuses on the interdisciplinary skill development of speech-language pathology graduate student clinicians and occupational therapy graduate student clinicians in the treatment of children with Autism Spectrum Disorder. This paper explains the significance of these disciplines in the treatment of Autism before giving the results of the study. For the present study, data was collected at James Madison University’s Summer Autism Camp over a four-week period. There were ten speech-language pathology (SLP) clinicians that received the survey and eleven children with Autism that were enrolled in the program. It was hypothesized that the SLP clinicians would display skill …


Facilitating Transitions Through The Use Of Multimodal Intervention For A Child With Autism, Alexis E. Anderson May 2017

Facilitating Transitions Through The Use Of Multimodal Intervention For A Child With Autism, Alexis E. Anderson

Senior Honors Projects, 2010-2019

Children with Autism Spectrum Disorder (ASD) have difficulty adapting to changes in routine, to the extent that they can struggle while transitioning out of one activity and into another. The inability to transition independently from one activity to the next can lead to negative behaviors, strained teacher-student relationships, and a loss of educational time in the classroom. The present study aimed to increase a six year old child’s independence while decreasing his problem behaviors observed during his transitions throughout the day at an autism clinic. A multimodal intervention along with a modified multimodal intervention was used to increase independence while …


Initiating Conversation By A Kindergarten-Aged Child With Autism Spectrum Disorder, Eliana A. Segal May 2016

Initiating Conversation By A Kindergarten-Aged Child With Autism Spectrum Disorder, Eliana A. Segal

Senior Honors Projects, 2010-2019

Children with Autism Spectrum Disorder (ASD) have social skill deficits that are often manifested in a failure to achieve normal back-and-forth conversation. They rarely initiate social interactions and often show little responsiveness to others. This can extinguish the social initiations of their peers, leading to great difficulty making friends. The purpose of the present study was to teach a child with ASD at an inter-professional autism clinic how to initiate and reciprocate a social conversation. A prompt fading procedure was implemented during training sessions to build a set of social skills into the child’s repertoire. The intervention provided social attention …


The Effectiveness Of Social Stories On Children With Autism Spectrum Disorder: A Literature Review, Caroline E. Johnson May 2015

The Effectiveness Of Social Stories On Children With Autism Spectrum Disorder: A Literature Review, Caroline E. Johnson

Senior Honors Projects, 2010-2019

The primary goal of Social Stories is to address debilitating difficulties and are written with the goal of objectively sharing important social information with individuals with ASD (Gray, 1998). The purpose of this literature review was to look at the effectiveness of Social Stories on children with autism.