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Photodynamic Therapy With Topical Aminolevulinic Acid Vs Placebo In The Treatment Of Actinic Keratosis, Michelle Nguyen, Katherine Shook

Physician Assistant Capstones, 2020-current

Objective: Assessing the effectiveness of photodynamic therapy with aminolevulinic acid versus placebo in the complete clearance rate of actinic keratosis.Design: Systematic literature review. Methods: An initial literature search was performed using Google Scholar using terms “photodynamic therapy”, “aminolevulinic acid,” “randomized control trial”, “actinic keratosis”, “clearance efficacy”, “safety”, “field treatment”, and “placebo”. An additional search using PubMed was performed using the same terms. Studies were excluded if they were performed on non-human subjects, did not use aminolevulinic acid as their photosensitizer, used organ transplant recipients, compared efficacy to alternate treatment modalities, used alternative light source such as laser or daylight, …