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Iowa State University

Life Sciences

Animal Science

1998

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Photoactivated Antiviral And Antitumor Compositions, George A. Kraus, Susan L. Carpenter, Jacob W. Petrich Jul 1998

Photoactivated Antiviral And Antitumor Compositions, George A. Kraus, Susan L. Carpenter, Jacob W. Petrich

Iowa State University Patents

Disclosed herein are compounds, compositions, and methods to inactivate a virus and destroy tumor cells. The methods involve the addition into the cell of a compound containing a photosensitizing chemical and an energy donating chemical, optionally linked by a chemical tether. Also introduced into the cell are means to chemically activate the energy donating chemical which photoactivates the photosensitizing chemical which then destroys the tumor or virus. The photosensitizing chemical is preferably hypericin, porphyrin, or an analog and the energy donating chemical is preferably luciferin or an analog. Methods for synthesizing the chemicals are also disclosed. Further, the energy donating ...


Photoactivated Antiviral And Antitumor Compositions, George A. Kraus, Susan L. Carpenter, Jacob W. Petrich Jul 1998

Photoactivated Antiviral And Antitumor Compositions, George A. Kraus, Susan L. Carpenter, Jacob W. Petrich

Iowa State University Patents

Disclosed herein are compounds, compositions, and methods to inactivate a virus and destroy tumor cells. The methods involve the addition into the cell of a compound containing a photosensitizing chemical and an energy donating chemical, optionally linked by a chemical tether. Also introduced into the cell are means to chemically activate the energy donating chemical which photoactivates the photosensitizing chemical which then destroys the tumor or virus. The photosensitizing chemical is preferably hypericin, porphyrin, or an analog and the energy donating chemical is preferably luciferin or an analog. Methods for synthesizing the chemicals are also disclosed. Further, the energy donating ...


Demonstration Of An Annual Forage Crop Integrated With Crop And Livestock Enterprises, Richard M. Cruse, Mark S. Honeyman, Mohammad Ghaffarzadeh Jan 1998

Demonstration Of An Annual Forage Crop Integrated With Crop And Livestock Enterprises, Richard M. Cruse, Mark S. Honeyman, Mohammad Ghaffarzadeh

Leopold Center Completed Grant Reports

Using a more diverse cropping system, such as strip intercropping, to produce forages for feeding livestock can create a more sustainable, environmentally friendly farming system. Strip intercropping of corn, soybeans, and oats underseeded with berseem clover was used to demonstrate agronomic and environmental benefits of a more varied cropping system. This system produces oat/ berseem clover soilage (green-chop) that can be utilized to feed beef cattle.