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Hemoglobin And The Host Pathogen Interactions In Streptococcus Pneumoniae: A New Paradigm, Fahmina Akhter
Hemoglobin And The Host Pathogen Interactions In Streptococcus Pneumoniae: A New Paradigm, Fahmina Akhter
Biology Dissertations
Abstract withheld.
A Computation Study Of Biofilm Development And Dispersal, Howard Smith
A Computation Study Of Biofilm Development And Dispersal, Howard Smith
Mathematics Dissertations
Bacterial biofilms are a structured population of bacteria adhered to a biotic or abiotic surface. Bacteria establish a biofilm by encasing themselves in a self-secreted matrix of extra polymeric substance. The matrix, composed primarily of polysaccharides and protein, confers to the individual bacterium enhanced protection from environmental insults. These insults would otherwise be detrimental to the bacteria if they were not part of the biofilm. To properly time when it is most beneficial to establish a biofilm and carry out other process, bacteria have developed a means to communicate using signaling molecules termed autoinducers. These signaling molecules help bacteria to …
Effects Of Escapin Intermediate Products (Eip-K) On Biofilms Of Pseudomonas Aeruginosa, Marwa Nabil Abdelaziz Ahmed
Effects Of Escapin Intermediate Products (Eip-K) On Biofilms Of Pseudomonas Aeruginosa, Marwa Nabil Abdelaziz Ahmed
Biology Theses
Escapin is an L-amino acid oxidase that produces antimicrobial metabolites collectively called “Escapin Intermediate Products” (EIP-K). EIP-K and H2O2 together were previously shown to be bactericidal towards diverse planktonic bacteria. The present work investigates the ability of EIP-K and H2O2 to antagonize bacterial biofilms, using Pseudomonas aeruginosa as a model. The project had three aims: 1) determine the most effective concentrations of EIP-K and H2O2 necessary to break down existing P. aeruginosa biofilms, using a crystal violet assay; 2) examine the ability of EIP-K + H2O2 to inhibit …
The Influences Of Luxs In Escherichia Coli Biofilm Formation And Improving Teacher Quality Through The Bio-Bus Program, Chandan Morris Robbins
The Influences Of Luxs In Escherichia Coli Biofilm Formation And Improving Teacher Quality Through The Bio-Bus Program, Chandan Morris Robbins
Biology Dissertations
The objectives of this work are: 1) to agarose-stabilize fragile biofilms for quantitative structure analysis; 2) to understand the influences of LuxS on biofilm formation; 3) to improve teacher quality by preparing Georgia’s middle school science teachers to integrate inquiry-based, hands-on research modules in the classroom. Quantitative digital image analysis demonstrated the effectiveness of the agarose stabilization technique for generating reproducible measurements of three dimensional biofilm structure. The described method will also benefit researchers who transport their flow cell-cultivated biofilms to a core facility for imaging. AI-2-dependent and independent effects of LuxS on biofilm-related phenotypes were revealed, suggesting that LuxS …
The Role Cranberry Proanthocyanidins Play In The Primary Attachment Of Bacteria To Surfaces: Bacillus Cereus Model, Anthony Robert Jones
The Role Cranberry Proanthocyanidins Play In The Primary Attachment Of Bacteria To Surfaces: Bacillus Cereus Model, Anthony Robert Jones
Biology Dissertations
The development of a proanthocyanidin (PAC) treatment, along with the understanding of its mechanism of action, would provide an alternative method of preventing attachment to and colonization of surfaces by microorganisms, as well as potentially disrupting preexisting biofilms. The purpose of this research is to examine the role a cranberry proanthocyanidin plays in the primary attachment of Bacillus cereus to an abiotic surface. This technology could be employed in food processing plants where a premium is placed on maintaining a sanitized work environment to prevent product contamination. A biofilm assay showed that a surface treated with proanthocyanidins actually promoted rather …
The Role Of Autoinducer-2 In Escherichia Coli Biofilm Formation And The Discovery Of A Plant-Derived Quorum Sensing Inhibitor, Chen Niu
Biology Dissertations
The objectives of this work are: 1) to determine whether plant essential oil components influence the ability of Escherichia coli and several Pseudomonas species to form biofilms, and inhibit bacterial quorum sensing; 2) to understand the role of autoinducer-2 (AI-2) in biofilm formation by E. coli W3110. The biofilm formation assays determined that cinnamon, cassia and citronella oils differentially affected growth-normalized biofilm formation by E. coli. Cinnamaldehyde (CA) also inhibited the swimming motility of E. coli. Subinhibitory concentrations of CA were effective at inhibiting two types of acyl homoserine lactone (HSL) mediated quorum sensing (QS), and also AI-2 mediated QS. …