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Task Residual Functional Connectivity In Language And Attention Networks, Stella Tran
Task Residual Functional Connectivity In Language And Attention Networks, Stella Tran
Psychology Theses
The present study compared network specificity between task-residual and resting state data types. Task-residual data capitalizes on the remaining variance after the mean task-related signal is removed from the time series. This study also examined how inter- and intrahemispheric connectivity (bilateral homologous regions and regions contained within the same hemisphere, respectively) within the language and attention networks change as a result of age. Task-residual functional connectivity evidenced stronger laterality of the language and attention connections and thus greater network specificity than resting state functional connectivity of the same connections. Using task-residual data may be optimal for characterizing the synchronized fluctuations …
Successful Sexual Aging: A Feminist Gerontological Examination Of Sexual Behavior And Health, Christina Barmon
Successful Sexual Aging: A Feminist Gerontological Examination Of Sexual Behavior And Health, Christina Barmon
Sociology Dissertations
As gerontology has shifted from emphasizing the problems of aging to exploring how older adults can thrive, researchers have increased their attention on new issues including sexuality and aging. A sometimes explicit, but often implicit assumption in this research, is that sex is good for you—that it is an integral part of a full and healthy life or successful aging. Although successful aging is one of the most commonly cited theories in social gerontology (Alley et al. 2010), it has not gone without criticism (Martinson and Berridge 2014). Using an unrefined successful aging framework for sex research has the potential …
Modeling Non-Linear Relationships Between Dna Methylation And Age: The Application Of Regularization Methods To Predict Human Age And The Implication Of Dna Methylation In Immunosenescence, Nicholas Johnson
Public Health Theses
Background: Gene expression is regulated via highly coordinated epigenetic changes, the most studied of which is DNA methylation (DNAm). Many studies have shown that DNAm is linearly associated with age, and some have even used DNAm data to build predictive models of human age, which are immensely important considering that DNAm can predict health outcomes, such as all-cause mortality, better than chronological age. Nevertheless, few studies have investigated non-linear relationships between DNAm and age, which could potentially improve these predictive models. While such investigations are relevant to predicting health outcomes, non-linear relationships between DNAm and age can also add to …