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Relationship Of Blood And Urinary Manganese Levels With Cognitive Function In Elderly Individuals In The United States By Race/Ethnicity, Nhanes 2011–2014, Arturo J. Barahona, Zoran Bursac, Emir Veledar, Roberto Lucchini, Kim Tieu, Jason R. Richardson
Relationship Of Blood And Urinary Manganese Levels With Cognitive Function In Elderly Individuals In The United States By Race/Ethnicity, Nhanes 2011–2014, Arturo J. Barahona, Zoran Bursac, Emir Veledar, Roberto Lucchini, Kim Tieu, Jason R. Richardson
Department of Biostatistics Faculty Publications
Manganese (Mn) is an essential metal with a biphasic relationship with health outcomes. High-level exposure to Mn is associated with manganism, but few data explore the effects of chronic, lower-level Mn on cognitive function in adults. We sought to determine the relationship between blood/urinary manganese levels and cognitive function in elderly individuals using 2011–2014 data from the National Health and Nutrition Examination Survey (NHANES). Weighted multivariate regression models were used to determine correlations, adjusting for several covariates. Blood Mn was inversely associated with the Consortium to Establish a Registry for Alzheimer’s Disease (CERAD) immediate learning of new verbal information (p-value …