Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network

Open Access. Powered by Scholars. Published by Universities.®

Clemson University

Theses/Dissertations

2014

Bioreactor

Articles 1 - 2 of 2

Full-Text Articles in Entire DC Network

An Engineering Approach To Forensic Methods: The Citrate Method For Postmortem Interval Determination, Melissa Dunphy May 2014

An Engineering Approach To Forensic Methods: The Citrate Method For Postmortem Interval Determination, Melissa Dunphy

All Theses

The Postmortem Interval (PMI) is the amount of time between the death of an individual and the discovery of the remains. Existing forensic techniques for the determination of the PMI are limited once soft tissue fully decays [31, 32]. A novel technique has recently been developed using the molecule Citrate (C6H8O7) to calculate the Postmortem Interval (PMI) [26]. Currently, this method cannot be practically applied due to the limited understanding of different forensic environments on the biochemistry of postmortem bone. In addition, further understanding of bone citrate measurement methods is needed to determine a practical field measurement approach. This study …


Design And Implementation Of A Real-Time Adaptive Oxygen Transfer Rate Estimator, Li Wang May 2014

Design And Implementation Of A Real-Time Adaptive Oxygen Transfer Rate Estimator, Li Wang

All Theses

Oxygen transfer rate (OTR) is the most signicant signal for aerobic bioprocess control, since most microbic metabolic activity relies on oxygen consumption. However, accurate estimation of OTR is challenging due to the difficulty of determining uncertain oxygen transfer parameters and system dynamics. This paper presents an adaptive estimator, which incorporates exhaust gas, stir speed and dissolved oxygen measurements, to predict the real-time OTR. The design of this estimator takes into account the headspace dilution effect, off-gas sensor dynamics and uncertain oxygen transfer parameters. Accurate and real-time OTR signal is derived by combining the low latency property of stir speed and …