Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 30 of 498

Full-Text Articles in Entire DC Network

The Development Of Face Morphing Task To Assess Self Other Differentiation, Esen Karan Sep 2019

The Development Of Face Morphing Task To Assess Self Other Differentiation, Esen Karan

Dissertations, Theses, and Capstone Projects

Self-Other Differentiation (SOD) refers to a developmental process of acquiring a consolidated, integrated, and individuated sense of self. SOD develops at a) perceptual (e.g., facial perception) and b) representational (e.g., traits, mental states, and beliefs) levels. Impairments in representational SOD (R-SOD) are associated with many forms of psychopathology, particularly borderline personality disorder (BPD) and narcissistic personality disorder (NPD). Few studies to date have examined the perceptual aspects of SOD (P-SOD), which are hypothesized to develop from infancy onwards in tandem and in interaction with R-SOD. Given that the human face is one of the key characteristics that humans use to …


Anxieties Of Incorporation: U.S. Territorialization And The Western Imaginary From The Louisiana Purchase To Moby-Dick, Diana Meckley Sep 2019

Anxieties Of Incorporation: U.S. Territorialization And The Western Imaginary From The Louisiana Purchase To Moby-Dick, Diana Meckley

Dissertations, Theses, and Capstone Projects

Anxieties of Incorporation: U.S. Territorialization and the Western Imaginary from the Louisiana Purchase to Moby-Dick investigates the impact of territorial expansion on authorial constructions of the continental west during the first half of the nineteenth century. As both a geophysical reality or an imagined space, the west functions as a site in which American writers negotiated their ambivalence over the promises and perils of continental aggrandizement and global imperialism. This project examines representative texts by James Fenimore Cooper, Francis Parkman, Susan Shelby Magoffin, and Herman Melville. In so doing, this dissertation traces how the western imaginaries these Anglo-American authors fashioned …


Exciton Polaritons In Two-Dimensional Transition Metal Dichalcogenides, Jie Gu Sep 2019

Exciton Polaritons In Two-Dimensional Transition Metal Dichalcogenides, Jie Gu

Dissertations, Theses, and Capstone Projects

Strong interaction between photons and excitons in semiconductors results in the formation of half-light half-matter quasiparticles termed exciton-polaritons. Owing to their hybrid character, they inherit the strong interparticle interaction from their excitonic (matter) component via Coulomb interaction while the photonic component lends the small mass (~105 times lighter than free electrons) and long propagation distances. Additionally, exciton-polaritons also carry properties of the host material excitons such as spin and valley polarization and can be probed via the photons that leak out of the cavities since the photon carries all the information owing to conservation laws. Since the first demonstration …


Staging English Affairs In Early Modern Italy: History, Politics, Drama, Fabio Battista Sep 2019

Staging English Affairs In Early Modern Italy: History, Politics, Drama, Fabio Battista

Dissertations, Theses, and Capstone Projects

This dissertation looks at the creation and dissemination of alternative versions of English history through the means of dramatic fiction, and contextualizes them in the panorama of the intellectual debates of seventeenth-century Italy. Staging English Affairs in Early Modern Italy studies the ways in which the reinvention of Tudor and Stuart affairs in dramatic literature mirrored the ambitions, fears, and fantasies of a century in disquieting transformation. This research documents how news and information from England entered the Italian states, how they were perceived, and what their repurposing can reveal about the potentialities of intercultural exchange. Anglo-inspired drama became a …


Systematics And Ecology Of The Andean Neotropical Schefflera (Araliaceae) With Globose Capitate Inflorescences And Use Of Niche Modeling For Iucn Red List Threat Assessment Of Plerandra Elegantissima (Araliaceae), Carlos V. Rodrigues Sep 2019

Systematics And Ecology Of The Andean Neotropical Schefflera (Araliaceae) With Globose Capitate Inflorescences And Use Of Niche Modeling For Iucn Red List Threat Assessment Of Plerandra Elegantissima (Araliaceae), Carlos V. Rodrigues

Dissertations, Theses, and Capstone Projects

Since the end of the 19thcentury, ScheffleraJ.R. Forst. & G. Forst.has been recognized as the largest and most wide-ranging genus of Araliaceae. It can be found throughout the humid tropics and subtropics, is not particularly diverse at low elevations in the warmest regions, and a few taxa extend into warm-temperate areas. As currently circumscribed, the genus contains 605 described species and many hundreds more awaiting formal description. However, a succession of phylogenetic studies have confirmed that Schefflera, as currently circumscribed,is polyphyletic, comprising five geographically centered lineages scattered across the phylogenetic tree of Araliaceae, and …


Getting The Benefit Of The Doubt: The Effect Of Randomization Ratio On The Placebo Response, Taiki Matsuura Sep 2019

Getting The Benefit Of The Doubt: The Effect Of Randomization Ratio On The Placebo Response, Taiki Matsuura

Dissertations, Theses, and Capstone Projects

Placebos are commonly employed in clinical trials as inactive treatments to which experimental treatments are compared against in order to control for psychological “noise.” Randomized double-blind placebo control studies are considered the “gold standard” in epidemiologic research because they can provide the strongest possible evidence of causation if designed correctly (Hulley, Cummings, Browner, & Grady, 2007). One phenomenon that poses a threat to the integrity of this evidence is the placebo response (PR), or referred to as the “placebo effect.” Expectancy is considered a central PR mechanism and boasts the most empirical support among all proposed mechanisms. Expectancy is not …


To See Again: Vision And Revelation In American Poetics, Emily C. Raabe Sep 2019

To See Again: Vision And Revelation In American Poetics, Emily C. Raabe

Dissertations, Theses, and Capstone Projects

With this project, I am arguing for a particularly American visual poetics that dwells in the state of suspension implied by attention, quivering between wonder and contemplation, immobility and unfixity as it seeks to reveal, as Maurice Merleau-Ponty writes in his 1945 The Phenomenology of Perception, the world which is “always ‘already there’ before reflection begins — as an inalienable presence.”[1] Grounded in visual theory, the project pairs poets and artists, searching not for similitude, but rather examining resemblance, difference, and most important, relation. Susan Howe, one of my guides for this project, writes that, “immense perspectives …


Men Set On Fire. Algernon Sidney & John Adams: Remodeling Anglo-American Republicanism, Deborah B. Charnoff Sep 2019

Men Set On Fire. Algernon Sidney & John Adams: Remodeling Anglo-American Republicanism, Deborah B. Charnoff

Dissertations, Theses, and Capstone Projects

This dissertation systematically examines the republican political ideas of the relatively unknown seventeenth-century English aristocratic Algernon Sidney, a passionate author and political activist who was executed for his ideas, and the famous but generally misunderstood eighteenth-century American revolutionary, Founder, and second President of the United States, John Adams. Republicanism is an entangled field of intellectual history in which historians, political scientists, legal scholars, and others have grappled for years, often without regard to the work of those in disciplines other than their own; yet we have consistently failed to take into account critical elements that inform the tradition, indeed, one …


Effects Of Pre-Tests And Feedback On Performance Outcomes In Massive Open Online Courses:What Works And What Doesn’T?, Maria Janelli Sep 2019

Effects Of Pre-Tests And Feedback On Performance Outcomes In Massive Open Online Courses:What Works And What Doesn’T?, Maria Janelli

Dissertations, Theses, and Capstone Projects

This experimental study examined the effects of pre-tests and feedback on learning outcomes in a five-week massive open online course (MOOC). The participants (N = 399) were adults from around the world who self-enrolled in the American Museum of Natural History’s (AMNH) climate change MOOC (called Our Earth’s Future) offered on the Coursera platform. Participants were randomly assigned to one of four conditions. Learners in the first treatment group took pre-tests without receiving feedback. Learners in the second treatment group took pre-tests and received basic (correct/incorrect) feedback. Learners in the third treatment group took pre-tests and received elaborate feedback. The …


The Distribution, Fractionation, And Application Of The 210po/210pb System: Insights From Three Geotraces Transects, Yi Tang Sep 2019

The Distribution, Fractionation, And Application Of The 210po/210pb System: Insights From Three Geotraces Transects, Yi Tang

Dissertations, Theses, and Capstone Projects

The sinking flux of particles is an important pathway for the removal of carbon and other elements from the surface ocean via the biological pump. The 210Po/210Pb disequilibrium method can be used to study particle export at high spatial resolution over the time scale of months. The distribution of 210Po and 210Pb activity was measured during two GEOTRACES transects of the North Atlantic and one GEOTRACES transect of the eastern tropical South Pacific. This dissertation aimed to advance the knowledge and improve methods of the application of the 210Po/210Pb pair to quantify …


Promoting Inclusion In A "Struggling School": Supporting Co-Teachers Through Critical Appreciative-Inquiry Based Professional Development, Louis Olander Sep 2019

Promoting Inclusion In A "Struggling School": Supporting Co-Teachers Through Critical Appreciative-Inquiry Based Professional Development, Louis Olander

Dissertations, Theses, and Capstone Projects

This dissertation explores the extent to which the beliefs and practices of teachers who work in a “struggling” school can be shifted towards inclusiveness through an action research based professional development program. The school was struggling in that it was charged with the education of children who are marginalized by a range of social forces while simultaneously accountable to institutional priorities. Broadly speaking, these institutional priorities preferred behaviorist punishment and technocratic approaches to meeting student needs, devaluing and decontextualizing students’ proficiencies as test scores and special education labels, in turn impeding inclusive change. Over the course of four months, an …


Restoring Solidarity: "Accountability" In Radical Leftist Subcultures, Sarah M. Hanks Sep 2019

Restoring Solidarity: "Accountability" In Radical Leftist Subcultures, Sarah M. Hanks

Dissertations, Theses, and Capstone Projects

In radical left activist subcultures, ‘accountability processes’ are a form of DIY transformative justice dealing with abuse and sexual assault, focusing on the needs of the ‘survivor’ and transformation of the ‘perpetrator.’ Within activism identifying abuse is particularly difficult because it means acknowledging abuse by a person considered politically virtuous. The specifics of a process are situational and provisional. The overwhelming pattern is male identified people abusing female identified, gender non-binary, and transgender people. My research examines why activists are developing processes to address problems and whether or not they are successful.

Within the subculture, the topic is important enough …


The Ferguson Effect In Contemporary Policing: Assessing Police Officer Willingness To Engage The Public, Christopher Mercado Sep 2019

The Ferguson Effect In Contemporary Policing: Assessing Police Officer Willingness To Engage The Public, Christopher Mercado

Dissertations, Theses, and Capstone Projects

Researchers suggest that as public scrutiny and video recording of violent/tumultuous police encounters increase, police would back away from proactive enforcement, resulting in an increase in crime—the Ferguson Effect. Recent scholarship refined these concerns over police disengagement with the study of de-policing, while other scholars explored police self-legitimacy, in order to explain law enforcement behavior, given the immediacy and ubiquity of social media and digital communication. This study surveyed 792 law enforcement officers from 10 different police agencies in the United States, to ascertain if police officers’ personal and contextual characteristics influence their decision to either take enforcement action (i.e., …


Essays In Empirical Economics, Agustin Indaco Sep 2019

Essays In Empirical Economics, Agustin Indaco

Dissertations, Theses, and Capstone Projects

This dissertation consists of two chapters that utilize distinct econometric methods and novel datasets.

In the first chapter, “From Twitter to GDP: Estimating Economic Activity From Social Media”, I collect all geo-located image tweets shared on Twitter in 2012-2013 to study whether the volume of tweets is a valid proxy for estimating current GDP in USD at the country level. My preferred model explains 94 percent of the cross-country variation and the residuals from the model are negatively correlated to a data quality index, indicating that my estimates of GDP are more accurate for countries with more reliable GDP data. …


Lead And Arsenic Contamination In Urban Soils In New York City, Anna Paltseva Sep 2019

Lead And Arsenic Contamination In Urban Soils In New York City, Anna Paltseva

Dissertations, Theses, and Capstone Projects

This dissertation examined total and bioaccessible soil lead (Pb) and arsenic (As) concentrations and their accumulation in commonly grown garden vegetables in New York City (NYC) metropolitan area. Direct oral ingestion of contaminated soil and consumption of plants that have accumulated Pb or As from underlying soil are known human exposure pathways in urban garden soils that often contain elevated levels of contaminants. The research had four components: (1) assessment of the variability of bioaccessible Pb in NYC urban soils; (2) field experiments to evaluate Pb stabilization and As mobilization by phosphate and alternative amendments; (3) development of a new …


Waiting: History, Fear, And Healing In Ballynafeigh / The Upper Ormeau Road Of Belfast, Northern Ireland, Molly J. Hurley-Depret Sep 2019

Waiting: History, Fear, And Healing In Ballynafeigh / The Upper Ormeau Road Of Belfast, Northern Ireland, Molly J. Hurley-Depret

Dissertations, Theses, and Capstone Projects

Based on fourteen months of ethnographic fieldwork in one neighborhood of Belfast called Ballynafeigh / the upper Ormeau Road in 2006–2007, I argue we need to pay closer attention to the “inconspicuous transformations” that may have been occurring in parallel to the official peace process. Walter Benjamin notes that “refined and spiritual things” do “make their presence felt in the class struggle. They manifest themselves in this struggle as courage, humour, cunning, and fortitude.” Benjamin states that “the past strives to turn toward that sun which is rising in the sky of history. A historical materialist must be aware of …


Music And Jewish Practice In Contemporary Istanbul: Preserving Heritage, Bending Tradition, Joseph M. Alpar Sep 2019

Music And Jewish Practice In Contemporary Istanbul: Preserving Heritage, Bending Tradition, Joseph M. Alpar

Dissertations, Theses, and Capstone Projects

This dissertation is a study of ongoing transformations in the sacred musical repertoires practiced by ḥazzanim (synagogue cantors) and their synagogue congregations in Istanbul’s contemporary Jewish community. I argue that clergy and laypeople alike negotiate their religious identities as Turkish Jews in the musical choices they make. While many try to maintain the community’s local music tradition, rooted in makam—the Ottoman Turkish melodic system—others attempt to broaden their repertoire with musics from Israel, the United States, and Ḥabad Hasidic Judaism. I examine adjustments made to the musical components of ritual as responses to decades of Jewish religious life as …


Minimalistic Peptide-Based Supramolecular Systems Relevant To The Chemical Origin Of Life, Daniela Kroiss Sep 2019

Minimalistic Peptide-Based Supramolecular Systems Relevant To The Chemical Origin Of Life, Daniela Kroiss

Dissertations, Theses, and Capstone Projects

All forms of life are based on biopolymers, which are made up of a selection of simple building blocks, such as amino acids, nucleotides, fatty acids and sugars. Their individual properties govern their interactions, giving rise to complex supramolecular structures with highly specialized functionality, including ligand recognition, catalysis and compartmentalization. In this thesis, we aim to answer the question whether short peptides could have acted as precursors of modern proteins during prebiotic evolution. Using a combination of experimental and computational techniques, we screened a large molecular search space for peptide sequences that are capable of forming supramolecular complexes with adenosine …


The Impact Of Racial Microaggressions And Major Discriminatory Events On Mental Health, Florence Lui Sep 2019

The Impact Of Racial Microaggressions And Major Discriminatory Events On Mental Health, Florence Lui

Dissertations, Theses, and Capstone Projects

The current study, a secondary data analysis, sought to determine the number and nature of latent groups for experiences of spectrum racial discrimination (i.e., both major and microaggressive racial discrimination) in a sample of emerging adults from a people of color (POC)-majority public university setting in the United States, and to understand the role of socio-demographic variables in defining each group. In addition, the study aimed to ascertain the extent to which endorsing spectrum racial discrimination experiences predicted anxiety and/or depression above the effects of general, non-race-related stress. Finally, the analyses gauged the mediating and/or moderating role of coping in …


Assessment Of Third Wave Therapy Assumptions About The Relation Between Emotional Schemas And Psychoemotional Functioning, Emily Rachel Edwards Sep 2019

Assessment Of Third Wave Therapy Assumptions About The Relation Between Emotional Schemas And Psychoemotional Functioning, Emily Rachel Edwards

Dissertations, Theses, and Capstone Projects

Recent advancements in emotion theory propose that emotional schemas – individualized conceptualizations and beliefs about emotions – serve a fundamental function in guiding psychoemotional processes. These advancements have progressed alongside the development of third-wave therapies, which presume emotional schemas to be deeply involved in perpetuating psychological distress and emotional dysfunction. To critically assess the validity of this presumption, the current research proposed and evaluated an integrative model of psychoemotional functioning.

Two studies were completed using a combination of behavioral, performance-based, and self-report measures of emotional schemas and psychoemotional functioning. Though further research is needed, results suggest the integrated model of …


Who Owned Waterloo? Wellington’S Veterans And The Battle For Relevance, Luke A. L. Reynolds Sep 2019

Who Owned Waterloo? Wellington’S Veterans And The Battle For Relevance, Luke A. L. Reynolds

Dissertations, Theses, and Capstone Projects

This dissertation examines the afterlife of the battle of Waterloo in the collective memory of Great Britain as well as the post-war lives of officers who fought there. Using a variety of techniques associated with cultural, social, and military history, it explores the concept of cultural ownership of a military event and contextualizes the relationship between Britain and her army in the nineteenth century, both at home and abroad. It argues that, almost immediately after the dust settled on the field of Waterloo, a variety of groups laid claim to different aspects of the ownership of the memory of the …


Does Ethnic Identity, In-Group Preference, And Acculturation Protect Latinas With A History Of Interpersonal Trauma From Developing Symptoms Of Ptsd?, Evelyn M. Ramirez Sep 2019

Does Ethnic Identity, In-Group Preference, And Acculturation Protect Latinas With A History Of Interpersonal Trauma From Developing Symptoms Of Ptsd?, Evelyn M. Ramirez

Dissertations, Theses, and Capstone Projects

Previous research suggests ethnic identity, a sense of belonging to a particular cultural group, may be protective against symptoms of post-traumatic stress disorder (PTSD). However, the role of ethnic identity, in-group preference (i.e., an individual’s preference for interactions with members of their own ethnic group) and acculturation (i.e., the level of comfort with the mainstream culture) have not been investigated as protective factors for Latinas with a history of interpersonal and sexual trauma. In this study, ethnic identity, in-group preference and acculturation were assessed via self-report on the Scale of Ethnic Experience in two samples of undergraduate Latina and non-Latina …


Examining The Use Of Hebephilia And Paraphilia Non-Consent In Sexually Violent Predator (Svp) Evaluations, Nicole Graham Sep 2019

Examining The Use Of Hebephilia And Paraphilia Non-Consent In Sexually Violent Predator (Svp) Evaluations, Nicole Graham

Dissertations, Theses, and Capstone Projects

Sexually violent predator (SVP) legislation requires, in part, that an individual has a mental abnormality which causes difficulty in controlling sexual behavior. Previous research has found paraphilia not otherwise specified (NOS) to be one of the most prevalent diagnoses proffered in SVP evaluations. Since these studies, however, the Diagnostic and Statistical Manual (DSM) has updated the paraphilia NOS diagnosis in two ways. First, this diagnosis has been divided into two new diagnoses—other specified paraphilic disorder (OSPD) and unspecified paraphilic disorder. Second, OSPD requires an added specifier to indicate the individual’s source of sexual arousal. To date, no study has systematically …


The Ends Of Plot: Rupture And Entanglement In L’Amica Geniale, Victor X. Zarour Zarzar Sep 2019

The Ends Of Plot: Rupture And Entanglement In L’Amica Geniale, Victor X. Zarour Zarzar

Dissertations, Theses, and Capstone Projects

This dissertation employs narrative theory to contextualize Elena Ferrante’s successful saga, L’amica geniale, within the larger tapestry of European novelistic discourses. It engages with conceptions of narrative structure put forth by critics like Ortega y Gasset, Brooks, and Winnett to understand how L’amica geniale offers cutting commentary on our exegetic practices and advances a geometry of narrative entanglement. I contend that Ferrante recuperates and italicizes nineteenth-century modes of storytelling, displaying a form of epistemological tension rooted in a movement away from a belief in plot’s semantic potentialities and into the postulation of a poetics of smarginatura or rupture. I …


Examining The Effects Of A Multi-Component Neurocognitive Intervention For School-Aged Children With Co-Occurring Adhd And Reading Difficulties, Alyssa L. Chimiklis Sep 2019

Examining The Effects Of A Multi-Component Neurocognitive Intervention For School-Aged Children With Co-Occurring Adhd And Reading Difficulties, Alyssa L. Chimiklis

Dissertations, Theses, and Capstone Projects

Objective: Children with attention deficit hyperactivity disorder (ADHD) frequently exhibit impairments in neurocognitive pathways (i.e., deficits in sustained attention, response inhibition, processing speed, working memory, and cognitive flexibility). There is also extensive support indicating that youth with co-occurring ADHD and reading difficulties share pathological pathways and exhibit deficits in executive functions. Neither behavioral nor pharmacological interventions have been able to fully address executive dysfunction and/or reading deficits in this population. Computerized neurocognitive training interventions have been explored as a treatment alternative for youth with pure ADHD and have demonstrated some merit. Conceptually, computerized neurocognitive training programs that target overlapping pathways …


Perceptions Of Sexual Violence: An Investigation Of Sexual Harassment, Sexual Coercion, And Sexting, Jennifer J. Mcmahon Sep 2019

Perceptions Of Sexual Violence: An Investigation Of Sexual Harassment, Sexual Coercion, And Sexting, Jennifer J. Mcmahon

Dissertations, Theses, and Capstone Projects

Perpetration of sexual violence is a serious concern in the US, with research indicating that a substantial portion of the population has experienced some type of sexual victimization. There is sparse research that examines perceptions and judgments of sexually inappropriate behaviors, and existing research does not take into account the impact of individual differences and contextual factors. This study examined whether individuals recognize different forms of sexual harassment, sexual coercion, and sexting as inappropriate, and how these perceptions are affected by sex, age, and relationship status. A mixed sample of undergraduate students and adults within the community completed an online …


Cyber-Narrative In Opera: Three Case Studies, Naomi Barrettara Sep 2019

Cyber-Narrative In Opera: Three Case Studies, Naomi Barrettara

Dissertations, Theses, and Capstone Projects

This dissertation looks at three newly composed operas that feature what I call cyber-narratives: a work in which the story itself is inextricably linked with digital technologies, such that the characters utilize, interact with, or are affected by digital technologies to such a pervasive extent that the impact of said technologies is thematized within the work. Through an analysis of chat rooms and real-time text communication in Nico Muhly’s Two Boys (2011), artificial intelligence in Søren Nils Eichberg’s Glare (2014), and mind uploading and digital immortality in Tod Machover’s Death and the Powers (2010), a nexus of ideologies surrounding voice, …


Words Are Found Responsible: Poetry's Jurisdiction And The Transformation Of Equal Rights, Talia Shalev Sep 2019

Words Are Found Responsible: Poetry's Jurisdiction And The Transformation Of Equal Rights, Talia Shalev

Dissertations, Theses, and Capstone Projects

Across various academic fields and from a range of political orientations, scholars note that a pervasive rights discourse shapes the imaginable horizons of identity, politics, and social life in the United States. Many critiques of rights since the 1970s highlight a particular conundrum of this rights culture: existing rights law and ubiquitous rights invocations fail to guarantee equal conditions for thriving across racialized and gendered axes of identity. Words Are Found Responsible: Poetry’s Jurisdiction and the Transformation of Equal Rights emphasizes and complicates elements of these critiques by reading poetry of the 1970s and 1980s in relation to shifting rights …


Murine Genetic Variance In Sugar And Fat-Conditioned Flavor Preferences: Roles Of Dopamine, Opioid And Nmda Receptors And Nutritive Sensing, Tamar T. Kraft Sep 2019

Murine Genetic Variance In Sugar And Fat-Conditioned Flavor Preferences: Roles Of Dopamine, Opioid And Nmda Receptors And Nutritive Sensing, Tamar T. Kraft

Dissertations, Theses, and Capstone Projects

As obesity and diabetes have emerged as a severe public health crisis, understanding the mechanisms underlying the consumption of sugars and fats has become a topic of vigorous study. From a biological standpoint, genetic dispositions, neurochemical and hormonal influences, and predetermined orosensory and postingestive signals that modulate the hunger and satiety process may govern physiological aspects of the obesity puzzle. In addition to an innate appetite and attraction for simple carbohydrates and fats, learning plays an important role in modulating preferences for sugar- and fat-rich foods in rodents, including inbred mouse strains. Marked genetic variance has been observed among murine …


Clinical Characteristics And Neuroanatomical Predictors Of Acute Antidepressant Outcome For Patients With Comorbid Depression And Mild Cognitive Impairment, Jeffrey N. Motter Sep 2019

Clinical Characteristics And Neuroanatomical Predictors Of Acute Antidepressant Outcome For Patients With Comorbid Depression And Mild Cognitive Impairment, Jeffrey N. Motter

Dissertations, Theses, and Capstone Projects

Background: Older adults presenting with both a depressive disorder (DEP) and cognitive impairment (CI) represent a unique, understudied population. The classification of cognitive impairment severity continues to be debated though it has recently been subtyped into late (LMCI) versus early (EMCI) stages. Previous studies have found associations between treatment outcome and both cortical thickness and white matter hyperintensities (WMH), though report inconsistent directionality and affected regions. In this study, we examined baseline clinical characteristics and neuroanatomical features as prognostic indicators for older adults with comorbid DEP and CI participating in an open antidepressant trial. EMCI is hypothesized to have greater …