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2024

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Effectiveness Of Empiric Carbapenem Versus Non-Carbapenem Therapy For Extended-Spectrum Β-Lactamase Producing Enterobacterales Infections In Non-Intensive Care Unit Patients: A Real-World Investigation In A Hospital With High-Prevalence Of Extended-Spectrum Β-Lactamase Producing Enterobacterales, Amy Y. Kang, Mary Elkomos, Danny Pham, Michelle Guerrero, Deborah Kupferwasser, Loren G. Miller Jun 2024

Effectiveness Of Empiric Carbapenem Versus Non-Carbapenem Therapy For Extended-Spectrum Β-Lactamase Producing Enterobacterales Infections In Non-Intensive Care Unit Patients: A Real-World Investigation In A Hospital With High-Prevalence Of Extended-Spectrum Β-Lactamase Producing Enterobacterales, Amy Y. Kang, Mary Elkomos, Danny Pham, Michelle Guerrero, Deborah Kupferwasser, Loren G. Miller

Pharmacy Faculty Articles and Research

Objective:

To investigate whether empiric carbapenem therapy, compared to empiric non-carbapenem therapy, was associated with improved clinical outcomes among hospitalized, non-intensive care unit (ICU) patients with extended-spectrum β-lactamase (ESBL)-producing Enterobacterales infections.

Methods:

We performed a retrospective cohort study of adult, non-ICU patients admitted with ESBL-producing Enterobacterales infections. Primary outcome was time to clinical stability from the first empiric antibiotic dose. Secondary outcomes were early clinical response and 30-day all-cause hospital readmission. We used multivariate regression methods to examine time to clinical stability.

Results:

Of the 142 patients, 59 (42%) received empiric carbapenems and 83 (58%) received empiric …


Perceptions Of Metabolic Syndrome Management Utilization In Relation To Patient Experience And Health-Related Quality Of Life, Olajide Adekunle, Jon C. Schommer, Yun Wang, Ismaeel Yunusa, Marc L. Fleming, Enrique Seoane-Vazquez, Lawrence M. Brown May 2024

Perceptions Of Metabolic Syndrome Management Utilization In Relation To Patient Experience And Health-Related Quality Of Life, Olajide Adekunle, Jon C. Schommer, Yun Wang, Ismaeel Yunusa, Marc L. Fleming, Enrique Seoane-Vazquez, Lawrence M. Brown

Pharmacy Faculty Articles and Research

Background

One factor for the poor health outcomes among adult people with metabolic syndrome (MetS) is poor utilization of disease management resources, which may be attributable to prior experience with pharmacists (PEwP) and perceptions of disease management resource utilization (PMU). Therefore, understanding patients' experience could be critical to improving their perceptions and promoting health outcomes.

Objectives

The study explored the influence of PEwP and PMU on the health-related quality of life (HRQoL) of people with MetS.

Methods

Data on perceptions of healthcare, medication, and pharmacy services utilization, PEwP, and HRQoL were collected using validated tools via an electronic survey. Chi-square …


Co-Designing Situated Displays For Family Co-Regulation With Adhd Children, Lucas M. Silva, Franceli L. Cibrian, Clarisse Bonang, Arpita Bhattacharya, Aehong Min, Elissa M. Monteiro, Jesus A. Beltran, Sabrina E. B. Schuck, Kimberley D. Lakes, Gillian R. Hayes, Daniel A. Epstein May 2024

Co-Designing Situated Displays For Family Co-Regulation With Adhd Children, Lucas M. Silva, Franceli L. Cibrian, Clarisse Bonang, Arpita Bhattacharya, Aehong Min, Elissa M. Monteiro, Jesus A. Beltran, Sabrina E. B. Schuck, Kimberley D. Lakes, Gillian R. Hayes, Daniel A. Epstein

Engineering Faculty Articles and Research

Family informatics often uses shared data dashboards to promote awareness of each other’s health-related behaviors. However, these interfaces often stop short of providing families with needed guidance around how to improve family functioning and health behaviors. We consider the needs of family co-regulation with ADHD children to understand how in-home displays can support family well-being. We conducted three co-design sessions with each of eight families with ADHD children who had used a smartwatch for self-tracking. Results indicate that situated displays could nudge families to jointly use their data for learning and skill-building. Accommodating individual needs and preferences when family members …


Socioeconomic Constraints On Low-Income Individuals' Perceptions Toward Food Safety, Uyen Thuy Xuan Phan, Cuc Thuy Thi Tran, Nguyet Minh Thi Nguyen May 2024

Socioeconomic Constraints On Low-Income Individuals' Perceptions Toward Food Safety, Uyen Thuy Xuan Phan, Cuc Thuy Thi Tran, Nguyet Minh Thi Nguyen

Food Science Faculty Articles and Research

Food safety has emerged as a critical concern in Vietnam, posing a significant threat to public health due to the prevalence of unsafe foods in the market. Among those most vulnerable to contaminated foods, low-income individuals are significantly affected. This study aimed to investigate the perceptions of food safety among this demographic, utilizing qualitative and quantitative approaches, including focus groups, survey questionnaires, and behavioral experiments using steamed bun as a stimulus. Participants were generally from low-income classes with certain variations in household monthly income. Results from focus groups and the survey highlighted that the factors influencing food purchases included perception …


Short-Term Benefits From Manual Therapy As An Adjunct Treatment For Persistent Postural-Perceptual Dizziness Symptoms: A Preliminary Prospective Case Series, Brent A. Harper, Larry Steinbeck May 2024

Short-Term Benefits From Manual Therapy As An Adjunct Treatment For Persistent Postural-Perceptual Dizziness Symptoms: A Preliminary Prospective Case Series, Brent A. Harper, Larry Steinbeck

Physical Therapy Faculty Articles and Research

Persistent dizziness and balance deficits are common, often with unknown etiology. Persistent Postural-Perceptual Dizziness (3PD) is a relatively new diagnosis with symptoms that may include dizziness, unsteadiness, or non-vertiginous dizziness and be persistent the majority of time over a minimum of 90 days. The purpose of this case series was to investigate short-term outcomes of reducing dizziness symptoms using a manual therapy intervention focused on restoring mobility in the fascia using a pragmatically applied biomechanical approach, the Fascial Manipulation® method (FM®), in patients with 3PD. The preliminary prospective case series consisted of twelve (n = 12) patients …


Disordered Eating In Transgender And Non-Binary Individuals, Vincent Marais May 2024

Disordered Eating In Transgender And Non-Binary Individuals, Vincent Marais

Student Scholar Symposium Abstracts and Posters

The purpose of this study was to examine the prevalence and nature of disordered eating behaviors and body image issues among transgender and non-binary individuals. It examined prevalence rates of different disordered eating behaviors to contrast them with rates among cisgender individuals. It also examined the ways in which gender-affirming healthcare and social acceptance of one's gender identity are correlated with improvement in eating habits and body image. For transgender and non-binary survey participants, the prevalence of disordered eating behaviors was compared to self-reported stage of transition. The prevalence of disordered eating behaviors among binary transgender participants at different stages …


Fantastical Fate: Contemporary Works Depicting Enlil, Daylen Motamed, Marissa Becher May 2024

Fantastical Fate: Contemporary Works Depicting Enlil, Daylen Motamed, Marissa Becher

Student Scholar Symposium Abstracts and Posters

It is known that the creation of Gods is prevalent, and almost essential to worldbuilding in fantasy novels. Some examples are the dwarves' Durin in Tolkein's The Lord of the Rings and Djel of the Fjerdans in Leigh Bardugo's Grishaverse novels. However, there is one popular god present in many modern fantasy series; the God of fate. In Ancient Mesopotamia, a God of fate was named Enlil. Enlil is known as the king of all Gods, as well as the God of wind and air. He decrees the fates and his word cannot be changed, as Enlil guards the tablets …


Moving Beyond Transactions: Understanding The Relationships Between College Access Professionals And Underrepresented College-Bound Families, Stephany Cuevas May 2024

Moving Beyond Transactions: Understanding The Relationships Between College Access Professionals And Underrepresented College-Bound Families, Stephany Cuevas

Education Faculty Articles and Research

Framed by family engagement frameworks, this study presents four types of interactions college access professionals (CAPs) have with the families of underrepresented college-going students—inconsistent communication, transactional exchanges, student-family mediation, and trusting relationships—to explore the nature of family-educator partnerships for students’ college access. Drawing from in-depth qualitative interviews with a diverse sample of 20 CAPs, this study demonstrates that the nature of these interactions and their corresponding family engagement practices are influenced by CAPs’ job requirements and previous experiences working with families. This ultimately shapes their ability to invest in and develop strong, trusting partnerships with students’ families. By understanding these …


Phi Beta Kappa Membership Roster, Phi Beta Kappa, Psi Of California Chapter At Chapman University May 2024

Phi Beta Kappa Membership Roster, Phi Beta Kappa, Psi Of California Chapter At Chapman University

Phi Beta Kappa Membership Roster

No abstract provided.


Demographic Effects On Climate Change Awareness, Alessandro Demoreno May 2024

Demographic Effects On Climate Change Awareness, Alessandro Demoreno

Student Scholar Symposium Abstracts and Posters

Does wealth blind us to the planet's plight, or does it empower action? In this research, I examine the extent to which people's income, political affiliation, and media consumption have affected their fear of climate change. Utilizing a mixed-methods approach, I will analyze data from the Wave 7 American Fears Methodology Report 2021; I hypothesize a strong negative correlation between income and fear of climate change. I will also examine the correlation between party affiliation and the level of fear. I hypothesize that those who identify as Democrats will score higher when it comes to fears relating to climate change …


Breaking Boundaries: Women In Mesopotamia, Eleanor Noble May 2024

Breaking Boundaries: Women In Mesopotamia, Eleanor Noble

Student Scholar Symposium Abstracts and Posters

We must examine women's contributions to society to comprehend women's roles and significance in ancient Mesopotamia. Women's roles in society and civilization are still frequently overlooked, both then and now. We must not ignore the importance of women's performance throughout history in these societies. Instead, we need to recognize these achievements made by women in the fields of politics, economic standpoints, and family life. We can distinguish the experiences of women in ancient Mesopotamia and contrast them with those of women in modern society by using textual sources and comparative analysis and research. Ancient writings, artwork, and literature can be …


A Content Analysis Of Common Relationship Challenges Among People Who Practice Polyamory, Kalyn Su, Sophie Camilleri May 2024

A Content Analysis Of Common Relationship Challenges Among People Who Practice Polyamory, Kalyn Su, Sophie Camilleri

Student Scholar Symposium Abstracts and Posters

Approximately 1 out of 9 people in the U.S. have engaged in polyamory (Moors et al., 2021), a relationship type in which all involved agree to have multiple romantic and/or sexual partners. Despite the commonness of polyamory, there are many misconceptions about the polyamorous experience. However, research has yet to examine common challenges that people engaged in polyamory endure. The goal of the present qualitative study was to identify the disadvantages and stressors of polyamory in order to shed light on the unique experiences of people in these relationships. 219 adults who were currently in a polyamorous relationship were asked …


The Gender Divide: Exploring Gender Patterns Of Perceived And Realistic Risks Of Murder By Unknown And Known Perpetrators, Haley Forth May 2024

The Gender Divide: Exploring Gender Patterns Of Perceived And Realistic Risks Of Murder By Unknown And Known Perpetrators, Haley Forth

Student Scholar Symposium Abstracts and Posters

In a society where vulnerability is often associated with femininity, women are depicted as helpless victims, which in turn underscores the gendered challenges faced by both men and women. It is thought that gender disparities among women increase the likelihood of fear and risk of murder victimization. Rather, both men and women face homicide at significant rates where gender vulnerability is correlated to different types of violence. In this paper, I examine the complexities of gendered perceptions of perceived and realistic risks behind the fear of being murdered by someone you know and murdered by a stranger. Relying on the …


Lifelong Movie Goers, Hardworking Filmmakers, And Oscars Discourse, Haley Kamola May 2024

Lifelong Movie Goers, Hardworking Filmmakers, And Oscars Discourse, Haley Kamola

Student Scholar Symposium Abstracts and Posters

This paper focuses on the discourse surrounding the Academy Awards, often referred to as the Oscars. The differences in discourse between people working in the film industry and those who watch movies are analyzed, as they represent the supplier and recipient of films and filmmaking. These two groups offer varied perspectives on the topic. The discourse of another group, a group in-between–student filmmakers–is also analyzed. To many people, what makes a film “good” is quite subjective, so the Academy Awards are often a subject of discourse. One particular focus of discourse will be the 2024 Academy Awards. There were a …


"And Then There Were None:" The Silencing And Censorship Of Translated Works Under Francisco Franco, Avery Austin May 2024

"And Then There Were None:" The Silencing And Censorship Of Translated Works Under Francisco Franco, Avery Austin

Student Scholar Symposium Abstracts and Posters

We tend to live under the assumption that translations will always attempt to be faithful to their original texts, blindly believing in the infallibility of the translator. However, in doing so, we ignore how translation can be used to take advantage of the reader – how can one know that a change has occurred in a translated work if they have no knowledge of the text’s original language? This paper studies the power dynamics of translation, and how it can be used as a tool to aid censorship. By focusing on translated literary works under the Franco regime, this work …


“Pro-Woman, Pro-Life”: Framing Of The Anti-Abortion Movement, Olivia Rivet May 2024

“Pro-Woman, Pro-Life”: Framing Of The Anti-Abortion Movement, Olivia Rivet

Student Scholar Symposium Abstracts and Posters

This project on the “Pro-Woman, Pro-Life" framing of the Anti-Abortion Movement uses James Paul Gee's theoretical lens on discourse analysis. My research corpus is comprised of historical, legislative, news, editorial, and film data. This project focuses on when the term "Pro-Woman" first appeared in the anti-abortion discourse and how it has been used to reinforce the Pro-Life stance. I argue that the phrase -- "Pro-Woman" -- is a discoursal strategy to appeal to women who are ideologically aligned with the Pro-Choice movement. According to the Pro-Woman, Pro-Life framework, no "feminist" would want to support a practice, such as abortion, that …


The Perception Of Children As Reliable Eyewitnesses, Shelby Mcdonald May 2024

The Perception Of Children As Reliable Eyewitnesses, Shelby Mcdonald

Student Scholar Symposium Abstracts and Posters

Eyewitness accounts have been integral to the criminal justice system. However, given that not every criminal case has forensic evidence that is available or admissible, the reliance on eyewitness accounts conjures questions about believability. This is an important area of research because the over-belief of witnesses may lead to wrongful convictions, yet under-belief may leave the victim without justice. The current study investigated how child-witness age, race, role as a witness (bystander versus victim), and the gender of the juror influenced the perception of child eyewitnesses through the lens of the Witness Credibility Model. Participants were presented with the testimony …


The Impact Of Childhood Trauma On Adult Attachment Style, Luella Rubin-Wylie, Desiree Crevecoeur-Macphail May 2024

The Impact Of Childhood Trauma On Adult Attachment Style, Luella Rubin-Wylie, Desiree Crevecoeur-Macphail

Student Scholar Symposium Abstracts and Posters

Repeated and complex childhood trauma can have devastating effects on individuals and their future relationships. Attachment styles are developed in the early years of an individual's life, and adverse experiences during these early years can negatively affect the attachment style that an individual develops. Various traumatic experiences during childhood, such as abuse/neglect, death/separation of parent, or witnessing domestic violence, may lead individuals to develop insecure attachment styles in their future romantic relationships. In many instances, experiencing childhood trauma can result in the development of aninsecure attachment style of anxious, avoidant, or disorganized. This study aimed to examine the impact of …


Assessing Brain Processing Deficits Using Neuropsychological And Vision-Specific Tests For Concussion, Brent A. Harper, Rahul Soangra Apr 2024

Assessing Brain Processing Deficits Using Neuropsychological And Vision-Specific Tests For Concussion, Brent A. Harper, Rahul Soangra

Physical Therapy Faculty Articles and Research

Introduction: Since verbal memory and visual processing transpire within analogous cerebral regions, this study assessed (i) if a visual function can predict verbal memory performance. It also hypothesized whether neurocognitive (e.g., ImPACT) tests focusing on the Visual Memory and Cognitive Efficacy Index will predict Verbal Memory scores and (ii) if vision metrics and age can identify individuals with a history of concussion. Finally, it also hypothesized that King–Devick and near point of convergence scores alongside age considerations will identify candidates with a prior reported history of concussion. Materials and methods: This observational cohort assessed 25 collegiate ice hockey players prior …


The Spiritual Prodigy, The Reluctant Guru, And The Saint: Mirabai And Collaborative Leadership At Hari Krishna Mandir, Nancy M. Martin Apr 2024

The Spiritual Prodigy, The Reluctant Guru, And The Saint: Mirabai And Collaborative Leadership At Hari Krishna Mandir, Nancy M. Martin

Religious Studies Faculty Articles and Research

This article explores the life and influence of Indira Devi Niloy (1920–1997) who in 1949 began to encounter the sixteenth-century saint–poet Mirabai during her meditative trance states. She would recount songs, stories, and teachings that the saint gave to her as well as scenes from Mirabai’s life that she witnessed as an observer and at other times experienced directly as a participant. Their ongoing relationship would have a tremendous influence on Indira Devi as well as her guru Dilip Kumar Roy (1897–1980) and the increasingly international community that grew up around them. Their interactions and Indira Devi’s reports in turn …


Who Helps Tsimane Children And Adults?, Eric Schniter, Daniel K. Cummings, Paul L. Hooper, Maguin Gutierrez Cayuba, Jonathan Stieglitz, Benjamin C. Trumble, Hillard S. Kaplan, Michael D. Gurven Apr 2024

Who Helps Tsimane Children And Adults?, Eric Schniter, Daniel K. Cummings, Paul L. Hooper, Maguin Gutierrez Cayuba, Jonathan Stieglitz, Benjamin C. Trumble, Hillard S. Kaplan, Michael D. Gurven

ESI Working Papers

We consider several forms of helping behavior among Tsimane Amerindians of Bolivia, including provision of shelter, childcare, food, sickcare, loans, advice, and cultural influence. While kin selection theory is traditionally invoked to explain nepotistic nurturing of youngsters by closely related kin, much less attention has been given to understanding the help provided to children and adults by individuals without close genetic relatedness. To explain who provides the various forms of help that we consider, we evaluate support for several predictions derived from kin selection theory: that helpers are most often closely related and from an older generation, provide more help …


Harnessing Exosomes As A Platform For Drug Delivery In Breast Cancer: A Systematic Review For In Vivo And In Vitro Studies, Abdulwahab Teflischi Gharavi, Saeed Irian, Azadeh Niknejad, Keykavous Parang, Mona Salimi Apr 2024

Harnessing Exosomes As A Platform For Drug Delivery In Breast Cancer: A Systematic Review For In Vivo And In Vitro Studies, Abdulwahab Teflischi Gharavi, Saeed Irian, Azadeh Niknejad, Keykavous Parang, Mona Salimi

Pharmacy Faculty Articles and Research

Breast cancer remains a significant global health concern, emphasizing the critical need for effective treatment strategies, especially targeted therapies. This systematic review summarizes the findings from in vitro and in vivo studies regarding the therapeutic potential of exosomes as drug delivery platforms in the field of breast cancer treatment. A comprehensive search was conducted across bibliographic datasets, including Web of Science, PubMed, and Scopus, using relevant queries from several related published articles and the Medical Subject Headings Database. Then, all morphological, biomechanical, histopathological, and cellular-molecular outcomes were systematically collected. A total of 30 studies were identified based on the Preferred …


Cardiogpt: An Ecg Interpretation Generation Model, Guohua Fu, Jianwei Zheng, Islam Abudayyeh, Chizobam Ani, Cyril Rakovski, Louis Ehwerhemuepha, Hongxia Lu, Yongjuan Guo, Shenglin Liu, Huimin Chu, Bing Yang Apr 2024

Cardiogpt: An Ecg Interpretation Generation Model, Guohua Fu, Jianwei Zheng, Islam Abudayyeh, Chizobam Ani, Cyril Rakovski, Louis Ehwerhemuepha, Hongxia Lu, Yongjuan Guo, Shenglin Liu, Huimin Chu, Bing Yang

Mathematics, Physics, and Computer Science Faculty Articles and Research

Numerous supervised learning models aimed at classifying 12-lead electrocardiograms into different groups have shown impressive performance by utilizing deep learning algorithms. However, few studies are dedicated to applying the Generative Pre-trained Transformer (GPT) model in interpreting electrocardiogram (ECG) using natural language. Thus, we are pioneering the exploration of this uncharted territory by employing the CardioGPT model to tackle this challenge. We used a dataset of ECGs (standard 10s, 12-channel format) from adult patients, with 60 distinct rhythms or conduction abnormalities annotated by board-certified, actively practicing cardiologists. The ECGs were collected from The First Affiliated Hospital of Ningbo University and Shanghai …


3rd Place Contest Entry: From Film Sets To Front Lines And Back Again: Reinventing Star Image In Post-World War Ii Hollywood, Livia Belen Lozoya Apr 2024

3rd Place Contest Entry: From Film Sets To Front Lines And Back Again: Reinventing Star Image In Post-World War Ii Hollywood, Livia Belen Lozoya

Eric M. Scandrett Graduate Library Research Prize

This is Livia Lozoya's submission for the 2024 Eric M. Scandrett Graduate Research Prize, which won third place. It contains their essay on using library resources, their bibliography, and a summary of their research project on established movie stars who voluntarily left their lives of luxury to serve in World War II and returned to a changed postwar film industry, specifically James Stewart, Robert Montgomery, Marlene Dietrich, and Myrna Loy.

Livia is a student in the Masters of Arts in Film and Media Studies program at Chapman University. Their faculty mentor is Dr. Emily Carman. Her thesis, available here, …


2nd Place Contest Entry: Physician Visits For Patients With Diabetes By Gender, Age And Race In The United States, Daniel Umoru, Olajide Adekunle, Adeola Bakare Apr 2024

2nd Place Contest Entry: Physician Visits For Patients With Diabetes By Gender, Age And Race In The United States, Daniel Umoru, Olajide Adekunle, Adeola Bakare

Eric M. Scandrett Graduate Library Research Prize

This is Daniel Umoru, Olajide Adekunle, and Adeola Bakare's submission for the 2024 Eric M. Scandrett Graduate Research Prize, which won second place. It contains their essay on using library resources, their bibliography, and a summary of their research project (with Dr. Lawrence "LB" Brown) on the complex demographic landscape of diabetes prevalence in the United States.

Daniel, Adeola, and Olajide are doctoral students in the School of Pharmacy at Chapman University. Their faculty mentor is Dr. Enrique Seoane-Vazquez.


The Perception Of Children As Reliable Eyewitnesses, Shelby Mcdonald Apr 2024

The Perception Of Children As Reliable Eyewitnesses, Shelby Mcdonald

Psychology Student Papers and Posters

Eyewitness accounts have been integral to the criminal justice system. However, given that not every criminal case has forensic evidence that is available or admissible, the reliance on eyewitness accounts conjures questions about believability. This is an important area of research because the over-belief of witnesses may lead to wrongful convictions, yet under-belief may leave the victim without justice. The current study investigated how child-witness age, race, role as a witness (bystander versus victim), and the gender of the juror influenced the perception of child eyewitnesses through the lens of the Witness Credibility Model. Participants were presented with the testimony …


Bibliography For "Keeping The Rhythm Of Creativity: Celebrating The Performing Arts And Intellectual Property", Isabella Piechota, Arianna Tillman, Kalea Brown, Katherine Roth Apr 2024

Bibliography For "Keeping The Rhythm Of Creativity: Celebrating The Performing Arts And Intellectual Property", Isabella Piechota, Arianna Tillman, Kalea Brown, Katherine Roth

Library Displays and Bibliographies

A bibliography created to support a display about the performing arts and intellectual property at the Leatherby Libraries during April 2024 at the Leatherby Libraries at Chapman University.


Cross-Cousin Marriage Among Tsimane Forager–Horticulturalists During Demographic Transition And Market Integration, Arianna Dalzero, Bret A. Beheim, Hillard Kaplan, Jonathan Stieglitz, Paul L. Hooper, Cody T. Ross, Michael D. Gurven, Dieter Lukas Mar 2024

Cross-Cousin Marriage Among Tsimane Forager–Horticulturalists During Demographic Transition And Market Integration, Arianna Dalzero, Bret A. Beheim, Hillard Kaplan, Jonathan Stieglitz, Paul L. Hooper, Cody T. Ross, Michael D. Gurven, Dieter Lukas

ESI Publications

Although still prevalent in many human societies, the practice of cousin marriage has precipitously declined in populations undergoing rapid demographic and socioeconomic change. However, it is still unclear whether changes in the structure of the marriage pool or changes in the fitness-relevant consequences of cousin marriage more strongly influence the frequency of cousin marriage. Here, we use genealogical data collected by the Tsimane Health and Life History Project to show that there is a small but measurable decline in the frequency of first cross-cousin marriage since the mid-twentieth century. Such changes are linked to concomitant changes in the pool of …


Characterizing Antibiotic Regimen Modification Behavior, Patient Characteristics, And Outcomes For Patients With Gram-Negative Bacterial Infections, A Retrospective Single-Center Study, Jason Yamaki, Mirna Mikhail, Richard Beuttler, Philip Robinson, Emre Yücel, Alexandre H. Watanabe Mar 2024

Characterizing Antibiotic Regimen Modification Behavior, Patient Characteristics, And Outcomes For Patients With Gram-Negative Bacterial Infections, A Retrospective Single-Center Study, Jason Yamaki, Mirna Mikhail, Richard Beuttler, Philip Robinson, Emre Yücel, Alexandre H. Watanabe

Pharmacy Faculty Articles and Research

Few studies describe the frequency of antibiotic regimen modification behaviors in the acute care setting. We sought to ascertain patient and treatment characteristics, details of regimen modification, and clinical outcomes with antibiotic modifications. This retrospective study included patients admitted to Hoag Memorial Hospital from 1 January 2019–31 March 2021 with a complicated infection caused by a Gram-negative organism resistant to extended-spectrum cephalosporins or with the potential for resistance (AmpC producers). A total of 400 patients were included. The predominant sources were bloodstream (33%), urine (26%), and respiratory (24%), including patients with multiple sources. The most isolated organisms were Pseudomonas spp. …


Testing The Reliability Of Optical Coherence Tomography To Measure Epidermal Thickness And Distinguish Volar And Nonvolar Skin, Molly E. Baumann, Nina Rossa Haddad, Alyssa Salazar, W. Lee Childers, Shawn Farrokhi, Neil B. Goldstein, Brad D. Henderson, Lisa Reider, Richard E. Thompson, Michael S. Valerio, Christopher L. Dearth, Luis A. Garza, Major Extremity Trauma Research Consortium (Metrc) Mar 2024

Testing The Reliability Of Optical Coherence Tomography To Measure Epidermal Thickness And Distinguish Volar And Nonvolar Skin, Molly E. Baumann, Nina Rossa Haddad, Alyssa Salazar, W. Lee Childers, Shawn Farrokhi, Neil B. Goldstein, Brad D. Henderson, Lisa Reider, Richard E. Thompson, Michael S. Valerio, Christopher L. Dearth, Luis A. Garza, Major Extremity Trauma Research Consortium (Metrc)

Physical Therapy Faculty Articles and Research

In persons with limb loss, prosthetic devices cause skin breakdown, largely because residual limb skin (nonvolar) is not intended to bear weight such as palmoplantar (volar) skin. Before evaluation of treatment efficacy to improve skin resiliency, efforts are needed to establish normative data and assess outcome metric reliability. The purpose of this study was to use optical coherence tomography to (i) characterize volar and nonvolar skin epidermal thickness and (ii) examine the reliability of optical coherence tomography. Four orientations of optical coherence tomography images were collected on 33 volunteers (6 with limb loss) at 2 time points, and the epidermis …