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California Polytechnic State University, San Luis Obispo

Biomedical Engineering

Series

2006

Inhibition

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Neural-Electronic Inhibition Simulated With A Neuron Model Implemented In Spice, Robert B. Szlavik, Abuhanif K. Bhuiyan, Anthony Carver, Frank Jenkins Mar 2006

Neural-Electronic Inhibition Simulated With A Neuron Model Implemented In Spice, Robert B. Szlavik, Abuhanif K. Bhuiyan, Anthony Carver, Frank Jenkins

Biomedical Engineering

There have been numerous studies presented in the literature related to the simulation of the interaction between biological neurons and electronic devices. A complicating factor associated with these simulations is the algebraic complexity involved in implementation. This complication has impeded simulation of more involved neural-electronic circuitry and consequently has limited potential advancements in the integration of biological neurons with synthetic electronics. In this paper, we describe a modification to a previously proposed SPICE based Hodgkin-Huxley neuron model that demonstrates more physiologically relevant electrical behavior. We utilize this SPICE based neuron model in conjunction with an external circuit that allows for …