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Influence Of Night Work On Performance During Lunar Telerobotic Operations, Zachary Luke Glaros

Master's Theses

Real-time, reactive telerobotic mission control operations require personnel to actively operate remotely controlled vehicles or robots in real time. Due to the physical separation of the vehicle from the operator, such operations present additional factors that can influence fatigue (degraded mental performance) and workload (mental and physical cost of task requirements), making it difficult to assess how long an individual can conduct operations safely. The upcoming Volatiles Investigating Polar Exploration Rover will involve remotely controlling a lunar vehicle from an Earth-based mission control station. In order to determine how long personnel could successfully maintain alertness and performance while operating a …

Protocol For The Prognosticating Delirium Recovery Outcomes Using Wakefulness And Sleep Electroencephalography (P-Drows-E) Study: A Prospective Observational Study Of Delirium In Elderly Cardiac Surgical Patients, S Kendall Smith, Thomas Nguyen, Alyssa K Labonte, Mohammadmehdi Kafashan, Orlandrea Hyche, Christian S Guay, Elizabeth Wilson, Courtney W Chan, Anhthi Luong, L Brian Hickman, Bradley A Fritz, Daniel Emmert, Thomas J Graetz, Spencer J Melby, Brendan P Lucey, Yo-El S Ju, Troy S Wildes, Michael S Avidan, Ben J A Palanca

Open Access Publications

INTRODUCTION: Delirium is a potentially preventable disorder characterised by acute disturbances in attention and cognition with fluctuating severity. Postoperative delirium is associated with prolonged intensive care unit and hospital stay, cognitive decline and mortality. The development of biomarkers for tracking delirium could potentially aid in the early detection, mitigation and assessment of response to interventions. Because sleep disruption has been posited as a contributor to the development of this syndrome, expression of abnormal electroencephalography (EEG) patterns during sleep and wakefulness may be informative. Here we hypothesise that abnormal EEG patterns of sleep and wakefulness may serve as predictive and diagnostic …

Prescribing Laughter To Ameliorate Mental Health, Sleep, And Wellbeing In University Students: A Protocol For A Feasibility Study Of A Randomised Controlled Trial, Freda N. Gonot-Schoupinsky, Gulcan Garip, David Sheffield, Omar M. Omar, Teresa Arora

All Works

© 2020 Objectives: This research is the first study to investigate the potential effects of a laughter prescription on both psychological health and objective sleep parameters in university students. The primary objective is to evaluate the feasibility of prescribing laughter to inform a larger randomised controlled trial. Secondary objectives are to assess if a two-week laughter prescription improves subjective and objective sleep outcomes, wellbeing, and/or psychological health outcomes. Trial design: To assess the feasibility of a randomised controlled trial for laughter prescription in relation to sleep, psychological health, and wellbeing. Forty university students will be recruited and randomised to one …

Sleep Induction By Mechanosensory Stimulation In Drosophila., Arzu Öztürk-Çolak, Sho Inami, Joseph R. Buchler, Patrick D. Mcclanahan, Andri Cruz, Christopher Fang-Yen, Kyunghee Koh

Department of Neuroscience Faculty Papers

People tend to fall asleep when gently rocked or vibrated. Experimental studies have shown that rocking promotes sleep in humans and mice. However, the mechanisms underlying the phenomenon are not well understood. A habituation model proposes that habituation, a form of non-associative learning, mediates sleep induction by monotonous stimulation. Here, we show that gentle vibration promotes sleep in Drosophila in part through habituation. Vibration-induced sleep (VIS) leads to increased homeostatic sleep credit and reduced arousability, and can be suppressed by heightened arousal or reduced GABA signaling. Multiple mechanosensory organs mediate VIS, and the magnitude of VIS depends on vibration frequency …

Perceived Partner Responsiveness, Pain, And Sleep: A Dyadic Study Of Military-Connected Couples, Annamarie S. O'Neill, Cynthia Mohr, Todd Bodner, Leslie Hammer

Psychology Faculty Publications and Presentations

Objective: The health-promoting influence of supportive close relationships has been extensively documented, yet the mechanisms of this effect are still being clarified. Leading researchers have theorized that examining particular interpersonal interactions and the mediating intrapersonal processes they facilitate is the key to understanding how close relationships benefit health. The purpose of this study was to investigate the influence of perceived partner responsiveness (PPR) on pain and sleep quality via affect in a sample of veterans and spouses (collectively called military-connected couples). Method: Military-connected couples (N = 162) completed 32 days of daily diaries. Mediated actor-partner interdependence models were conducted using …

The Day-To-Day Impact Of Nighttime Noise Disturbances On College Students’ Psychological Functioning, Jack Peltz

Articles & Book Chapters

Objective: To understand environmental predictors (i.e., nighttime noise disturbance) of sleep health (i.e., restedness) in residential college students and its potential mental health consequences, this study examined daily variation in restedness upon awakening as a potential mediator between nightly environmental noise disturbances and daily fluctuations in depressive and anxiety symptoms.

Participants: The sample was comprised of 283 college students (M age = 19.9, SD  = 1.9; 79% female).

Methods: Multilevel structural equation modeling was conducted based on an initial self-report, online questionnaire and an online 7-day daily sleep (morning) and mood (evening) diary.

Results: Daily fluctuations in college students' reports …

Deliberation Enhances The Confirmation Bias In Politics, David L. Dickinson

ESI Publications

The confirmation bias, unlike other decision biases, has been shown both empirically and in theory to be enhanced with deliberation. This suggests that limited attention, reduced deliberation, or limited available cognitive resources may moderate this bias. We aimed to test this hypothesis using a validated confirmation bias task in conjunction with a protocol that randomly assigned individuals to one week of at-home sleep restriction (SR) or well-rested (WR) sleep levels. We also used a measure of cognitive reflection as an additional proxy for deliberation in our analysis. We tested the hypotheses that the confirmation bias would be stronger for WR …

A Longitudinal Descriptive Study On The Sleep Of Young Adults With Developmental Disabilities, Emily E. Grubbs

Theses and Dissertations

Sleep is vital for optimal physical and mental health, as well as cognitive and social functioning. Young adults with developmental disabilities (DD) are at greater risk for physical and mental health disorders and experience limitations in cognitive and social functioning in ways that can prevent participation in meaningful activities associated with young adulthood. Sleep literature has reflected that persons with DD experience worse sleep than persons without DD. Suboptimal sleep could compromise functionality and thus participation in young adulthood activities. Not much is known however of the nature of sleep problems experienced by young adults with DD. This study is …

Diet And Exercise: What To Eat And When, Brittany Allman

Diet, Food, Exercise, and Nutrition (D-FEND)

Learning Objectives:

Define nutrient timing

Understand the importance of nutrient timing

Understand the different types of carbohydrates

Understand how eating patterns can affect sleep

Conscious Perception And Implicit Memory Formation Of A Narrative Presented During Sleep, Sarah E. Hollywood

Electronic Thesis and Dissertation Repository

The present study sought to determine the extent of conscious awareness and implicit memory formation of a narrative presented during sleep. Participants were played an excerpt of J.D. Salinger’s Pretty Mouth and Green My Eyes while napping. Afterwards, participants completed a task designed to assess implicit memory to determine if they had formed any memories about words that were either directly stated in the story, or directly related to the plot. Participants who heard the story while asleep responded more quickly to words that had appeared in the story than to words from another story they had not heard. Exactly …

Sleep And Suicide: A Systematic Review And Meta-Analysis Of Longitudinal Studies, Richard T. Liu, Stephanie J. Steele, Jessica L. Hamilton, Quyen B.P. Do, Kayla Furbish, Taylor A. Burke, Ashley P. Martinez, Nimesha Gerlus

Psychology: Faculty Publications

The current review provides a quantitative synthesis of the empirical literature on sleep disturbance as a risk factor for suicidal thoughts and behaviors (STBs). A systematic search of PsycINFO, MEDLINE, and the references of prior reviews resulted in 41 eligible studies included in this meta-analysis. Sleep disturbance, including insomnia, prospectively predicted STBs, yielding small-to-medium to medium effect sizes for these associations. Complicating interpretation of these findings however, is that few studies of suicidal ideation and suicide attempts, as well as none of suicide deaths, assessed short-term risk (i.e., employed follow-up assessments of under a month). Such studies are needed to …

Age-Related Losses In Cardiac Autonomic Activity During A Daytime Nap, Pin-Chun Chen, Negin Sattari, Lauren N. Whitehurst, Sara C. Mednick

Psychology Faculty Publications

In healthy, young individuals, a reduction in cardiovascular output and a shift from sympathetic to parasympathetic (vagal) dominance is observed from wake into stages of nocturnal and daytime sleep. This cardiac autonomic profile, measured by heart rate variability (HRV), has been associated with significant benefits for cardiovascular health. Aging is associated with decreased nighttime sleep quality and lower parasympathetic activity during both sleep and resting. However, it is not known whether age-related dampening of HRV extends to daytime sleep, diminishing the cardiovascular benefits of naps in the elderly. Here, we investigated this question by comparing the autonomic activity profile between …

The Effects Of A Yoga Intervention, Karen R. Arrant, Mary W. Stewart

Journal of Interprofessional Practice and Collaboration

Sleep disturbance and stress in postmenopausal women pose physical, mental, and emotional health hazards. Researchers examined the effect of a yoga intervention on sleep, stress, anxiety, and depression in postmenopausal women. The study employed a randomized, controlled trial with: (1) a treatment group (yoga intervention) and (2) an attention-control group (health education). All participants completed three PROMIS® – Patient-Reported Outcomes Measurement Information System – tools and collected saliva samples before and after the eight-week intervention. The PROMIS® tools measured sleep, anxiety, and depression. Salivary alpha-amylase quantified sleep; salivary cortisol measured stress; and participants self-reported hours of sleep.

Thirty-one women completed …

Sleep Quality And The Prospective Pain-Fatigue Relationship Among Youth With Sickle Cell Disease, Julia D. Johnston

Theses and Dissertations

Youth with sickle cell disease (SCD) are at increased risk for poor psychosocial and functional outcomes due, in part, to disease effects like vaso-occlusive pain crises, fatigue, and poor sleep quality (Brown, 2006). A growing body of literature has examined temporal associations between pain, sleep quality, and mood using daily diary studies (Valrie, Gil, Redding-Lallinger, & Daeschner, 2007a; Valrie et al., 2019). These studies help to identify how symptoms are prospectively related to each other, but they are often limited to small sample sizes and may lack generalizability. Additionally, despite ubiquitous reports of fatigue among sickle cell patients, few studies …

It's Complicated: The Relationship Between Sleep And Alzheimer's Disease In Humans, Brendan P Lucey

Open Access Publications

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by an asymptomatic period of amyloid-β (Aβ) deposition as insoluble extracellular plaque, intracellular tau aggregation, neuronal and synaptic loss, and subsequent cognitive dysfunction and dementia. A growing public health crisis, the worldwide prevalence of AD is expected to rise from 46.8 million individuals affected in 2015 to 131.5 million in 2050. Sleep disturbances have been associated with increased future risk of AD. A bi-directional relationship is hypothesized between sleep and AD with sleep disturbances as either markers for AD pathology and/or a mechanism mediating increased risk of AD. In this review, …

Modulation Of Sleep-Courtship Balance By Nutritional Status In Drosophila, José M Duhart, Victoria Baccini, Yanan Zhang, Daniel R Machado, Kyunghee Koh

Farber Institute for Neuroscience Faculty Papers

Sleep is essential but incompatible with other behaviors, and thus sleep drive competes with other motivations. We previously showed Drosophila males balance sleep and courtship via octopaminergic neurons that act upstream of courtship-regulating P1 neurons (Machado et al., 2017). Here, we show nutrition modulates the sleep-courtship balance and identify sleep-regulatory neurons downstream of P1 neurons. Yeast-deprived males exhibited attenuated female-induced nighttime sleep loss yet normal daytime courtship, which suggests male flies consider nutritional status in deciding whether the potential benefit of pursuing female partners outweighs the cost of losing sleep. Trans-synaptic tracing and calcium imaging identified dopaminergic neurons projecting to …

An Investigation Of The Temporal Relationship Between Agitation And Sleep Disturbances, Emily Catherine Denning

Dissertations and Theses

Suicide rates in the United States have increased almost 30% since 1999, making it the tenth leading cause of death in the country. This problem is especially prominent for veterans of the U.S. Armed Forces, as veterans comprise 8.5% of the U.S. population, yet they account for 18% of all deaths by suicide. These increasing rates have spurred the need for a better understanding of suicide risk, especially for this high-risk group. Previous research has focused mostly on chronic risk factors, which are useful for identifying who from a population may be more likely to engage in suicidal behaviors, but …

Impact Of Metformin On Feeding, Behavior, And Metabolism In Drosophila Melanogaster., Erica E. Hassoun, Heba Kourhabi, Jason Bui Ho, Dae-Sung Hwangbo

Undergraduate Research Events

Metformin is a first-line drug used in the treatment of type II diabetes mellitus and is the 4th-most prescribed drug in the United States. It functions in lowering blood glucose levels and increasing insulin sensitivity. Despite its wide scale use, the degree to which it affects aspects of behavior and metabolism unrelated to diabetes is not fully understood.

Recent studies have attempted to fill this gap, particularly in the context of metformin’s impact on lifespan. We decided to extend this research by focusing on measurable behaviors as well as traits related to metabolism and physiology. Using the fruit fly Drosophila …

Insomnia Is Associated With Frequency Of Suicidal Ideation Independent Of Depression: A Replication And Extension Of Findings From The National Health And Nutrition Examination Survey, Zach Simmons, Lance D. Erickson, Dawson Hedges, Daniel Kay

Faculty Publications

Objective: Insomnia is associated with suicidality, although the mechanisms of this association are unclear. This study sought to replicate previous findings showing that insomnia symptoms but not sleep duration are associated with frequency of suicidal ideation in adults. We further investigated whether depression or sleep duration moderates the association between insomnia symptoms and frequency of suicidal ideation.

Materials and Methods: We used the 2005–2006 cycle of the National Health and Nutrition Examination Survey to replicate previously reported findings from the 2007–2008 cycle. We used ordered logistic regression to determine whether insomnia symptoms were associated with frequency of suicidal ideation independently …

Effect Of Chronotype On Sleep Quality In A Laboratory Setting, Brianna D. Harfmann, Natashia Swalve, John Mitrzyk, Alex Montoye

International Journal of Exercise Science

International Journal of Exercise Science 13(3): 1283-1294, 2020. Sleep is undoubtedly important for human health as insufficient sleep has been associated with a plethora of diseases. Adequate sleep assessment is critical in clinical and research settings, however current sleep assessment protocols fail to account for circadian rhythms, despite the fact that sleep is a well-recognized circadian process. Purpose: The purpose of this study was to determine if circadian parameters, such as chronotype, influence sleep quality in a sleep laboratory setting. Methods: In order to investigate this, twenty participants (10 men and 10 women) aged 18-31 years old had their sleep …

Disrupted Sleep And Associated Factors In Australian Dementia Caregivers: A Cross-Sectional Study, Aisling Smyth, Lisa Whitehead, Eimear Quigley, Caroline Vafeas, Laura Emery

Research outputs 2014 to 2021

BACKGROUND: Sleep disturbance is an issue reported by caregivers. Waking at night is a feature of dementia and by proxy, sleep disturbance among caregivers is reported to be high. Little is known about the characteristics of dementia caregivers' sleep and the factors that may influence sleep disruption. The purpose of this study was to investigate the sleep characteristics and disturbances of Australian caregivers of a person living with dementia. In addition, it evaluated the psychological wellbeing of caregivers by evaluating associations between mood and sleep in this population. METHODS: This study used a cross-sectional, descriptive, correlation design. Participants were recruited …

Impairment In Adult Adhd: Effects Of Adhd Symptoms, Executive Function, And Sleep, Morgan M. Dorr

Theses and Dissertations

While Attention-deficit/hyperactivity disorder (ADHD) remains one of the most common psychological disorders diagnosed, current understanding of the disorders expression and factors contributing to impairment in early adulthood remains limited. In an effort to better understand current issues with ADHD assessment and treatment in emerging adults, this study aimed to examine relationships between symptoms, executive function (EF), sleep, and impairment. Overall results of this study indicate that together, ADHD symptoms, EF, and sleep account for a significant proportion of variance in impairment. Additionally, results indicate that EF moderates the relationship between ADHD symptoms and impairment, and that sleep may be a …

Impact Of Sleep Duration, Sleep Quality, And Physical Activity On Obesity Indices Among Adolescents, Sarah Thompson

Theses and Dissertations

Adolescent prevalence of obesity and at-risk WC has continued to rise worldwide. Sleep duration, sleep quality, and physical activity have been hypothesized as contributing factors to this increase. PURPOSE: This study aimed to examine the sleep–obesity relation in adolescents. METHODS: Using data from the 2015-2016 NHANES(n=454; ages 16-18 years), the effect of sleep duration, sleep quality, and MVPA on BMI and WC by gender was analyzed using appropriate sampling weights. RESULTS: Longer sleep duration was associated with increased BMI (β=0.07; 0.065, p<0.05) and WC (β=0.069; 0.13, p<0.05) among males and females. Poor sleep quality was associated with increased BMI among males and females (β= 0.04; 0.08, p< 0.05). A significant main effect was observed across sleep duration, sleep quality and MVPA via multiple regression for both BMI and WC. CONCLUSIONS: For both males and females, BMI and WC were impacted by excessive sleep, poor sleep quality, and low MVPA, with greater associations among males.

Physical Activity, Sedentary Behavior, And Sleep Quality In Adults With Primary Hypertension And Obesity Before And After An Aerobic Exercise Program: Exerdiet-Hta Study, Aitor Martinez Aguirre-Betolaza, Iñigo Mujika, Paul Loprinzi, Pablo Corres, Ilargi Gorostegi-Anduaga, Sara Maldonado-Martín

Faculty and Student Publications

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Background: The purposes of the study were to: analyze, by objective (accelerometry) and subjective (International Physical Activity Questionnaire, IPAQ) methodologies, the physical activity (PA) and sedentary behavior (SB) in healthy adults (HEALTHY, n = 30) and individuals with primary hypertension (HTN) and overweight/obesity (n = 218); assess the effects of an aerobic exercise intervention on physical activity (PA), sedentary behavior (SB), and sleep quality in the HTN group; and evaluate the relationship between objectively measured and subjectively reported PA and SB. Methods: The measurements were performed before a 16-week exercise intervention …

Opioids Disrupt Sleep And Wakefulness In C57bl/6j Mice, Clarence E. Locklear

Masters Theses

Opioid use disorder (OUD) is a major public health burden. According to the National Institutes of Health (NIH), studies helping to understand the mechanisms of OUD will help improve prevention and treatment. Opioids long have been shown to disrupt sleep and sleep disruption enhances the likelihood of addiction relapse in humans. The NIH refers to the mouse as one of the most powerful animal systems to study because of the genetic homologies between human and mouse. Prior to the present research, no studies have quantified the effect of opioids on states of sleep and wakefulness in mice. The current study …

Chronic Pain, Sleep Disruption, And Work Performance In The Military, Jeffrey Ransom

Dissertations

Abstract

Background and Significance: Managing pain is a challenge for many organizations, including the U.S. military. The added complication of managing sleep disruption compounds the issue. Examining pain and sleep disruption in the context of work performance within the military is critical to understanding the impact of these conditions on our nation’s fighting forces.

Purpose: Examine the associations of chronic pain and sleep disruption in the context of work performance among active duty military service members.

Research Aims: 1) Describe sociodemographic characteristics, military service characteristics, clinical characteristics, and work performance of active duty service members, 2) Examine relationships between these …

Development And Analysis Of A Vibration Based Sleep Improvement Device, Benjamin John Himes

Theses and Dissertations

Many research studies have analyzed the effect that whole-body vibration (WBV) has on sleep, and some have sought to use vibration to treat sleep disorders such as insomnia. It has been shown that low frequencies (f < 2Hz) are generally sleep inducing, but oscillations of this frequency are typically difficult to achieve using electromagnetic vibration drives. In the research that has been performed, optimal vibration parameters have not been determined, and the effects of multiple vibration sources vibrating at different frequencies to induce a low frequency traveling wave have not been explored. Insomnia affects millions of people worldwide, and non-pharmacological treatment options are limited. A bed excited with multiple vibration sources was used to explore beat frequency vibration as a non-pharmacological treatment for insomnia. A repeated measures design pilot study of 14 participants with mild-moderate insomnia symptom severity was conducted to determine the effects of beat frequency vibration, and traditional standing wave vibration on sleep latency and quality. Participants were monitored using high-density electroencephalography (HD-EEG). Sleep latency was compared between treatment conditions. Trends of a decrease in sleep latency due to beat frequency vibration were found (p ≤ 0.181 for AASM latency, and p ≤ 0.068 for unequivocal sleep latency). Neural complexity during wake, N1, and N2 stages were compared using Multi-Scale Sample Entropy (MSE), which demonstrated significantly lower MSE between wake and N2 stages (p ≤ 0.002). Lower MSE was found in the transition from wake to N1 stage sleep but did not reach significance (p ≤ 0.300). During N2 sleep, beat frequency vibration shows lower MSE than the control session in the left frontoparietal region. This indicates that beat frequency vibration may lead to a decrease of conscious awareness during deeper stages of sleep. Standing wave vibration caused reduced Alpha activity and increased Delta activity during wake. Beat frequency vibration caused increased Delta activity during N2 sleep. These preliminary results suggest that beat frequency vibration may help individuals with insomnia symptoms by decreasing sleep latency, by reducing their conscious awareness, and by increasing sleep drive expression during deeper stages of sleep. Standing wave vibration may be beneficial for decreasing expression of arousal and increasing expression of sleep drive during wake, implying that a dynamic vibration treatment may be beneficial. The application of vibration treatment as part of a heuristic sleep model is discussed.

A Comparative Study Of Sleep And Diurnal Patterns In House Mouse (Mus Musculus) And Spiny Mouse (Acomys Cahirinus), Chanung Wang, Lauren E. Guerriero, Dillon M. Huffman, Asma'a A. Ajwad, Trae C. Brooks, Sridhar Sunderam, Ashley W. Seifert, Bruce F. O'Hara

Biomedical Engineering Faculty Publications

Most published sleep studies use three species: human, house mouse, or Norway rat. The degree to which data from these species captures variability in mammalian sleep remains unclear. To gain insight into mammalian sleep diversity, we examined sleep architecture in the spiny basal murid rodent Acomys cahirinus. First, we used a piezoelectric system validated for Mus musculus to monitor sleep in both species. We also included wild M. musculus to control for alterations generated by laboratory-reared conditions for M. musculus. Using this comparative framework, we found that A. cahirinus, lab M. musculus, and wild M. musculus were …

Psychological Climacteric Symptoms And Attitudes Toward Menopause Among Emirati Women, Amira Mohammed Ali, Afaf Hassan Ahmed, Linda Smail

All Works

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Menopause is an inevitable developmental event that women encounter at an age of 42–54 years. The drop of estrogen levels that accompanies cessation of menstruation is associated with multiple vasomotor, physical, neuropsychological, and sexual symptoms, which may hamper quality of life. This study aimed to examine the severity of psychological symptoms and their correlates among peri-and postmenopausal Emirati women (N = 60, mean age = 54.88 ± 6 years). Participants were interviewed using the Menopause-Specific Quality of Life (MENQOL) and attitudes toward menopause scale (ATMS). In four path analysis models, vasomotor …

Supporting Adequate Sleep In Patients Hospitalized With Psychiatric Illness Through A Nurse-Driven Protocol, Mary Perez

Doctor of Nursing Practice Scholarly Projects

Sleep is growing in recognition for its part in overall health. Sleep is essential to optimal functioning in all people. Its link to psychiatric illness makes it especially important to those in recovery. As we learn more about sleep and its effects, it is important for nurses and nurse leaders to become more acquainted with how sleep affects health and what can be done to initiate good sleep. Since sleep is complex and supporting sleep must be individualized to each person, having a good understanding of both subjects is necessary. Sleep hygiene is a set of environmental and behavioral interventions …