Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Entire DC Network
Natural Medicines, Neyda V. Gilman
Natural Medicines, Neyda V. Gilman
Library Scholarship
Natural Medicines is a robust and authoritative resource for information related to complementary and alternative medicines, natural therapies, natural ingredients, and natural products. The content is evidence-based with the aim of being as objective and unbiased as possible, and monographs in the database include references for the information provided (Natural Medicines 2019a). It is a fee-based subscription product, but pricing is generally fair and it can be bundled with other resources of interest. There are some inconveniences, such as not working with discovery services or allowing Boolean or quotation searching, but overall the database is easy to use, reliable, and …
Analysis For Science Librarians Of The 2018 Nobel Prize In Physiology Or Medicine: The Life And Work Of James P. Allison And Tasuku Honjo, Neyda V. Gilman
Analysis For Science Librarians Of The 2018 Nobel Prize In Physiology Or Medicine: The Life And Work Of James P. Allison And Tasuku Honjo, Neyda V. Gilman
Library Scholarship
On October 1, 2018, James P. Allison and Tasuku Honjo were awarded the 2018 Physiology or Medicine Nobel for their work leading to Immune Checkpoint Inhibition (ICI). ICI is the fourth pillar of cancer treatment and has been used to treat previously un-treatable cancers. Allison discovered that the protein CTLA-4 acts as a T cell brake while Honjo discovered another T cell brake, PD-1. Releasing these brakes allows the immune system to attack tumors, sometimes leading to complete elimination. While there is still more research to be done, Allison’s and Honjo’s work is a breakthrough in cancer immunotherapy.