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- Cytochrome P450; coumarins; docking; quantitative structure-activity relationship (QSAR); hologram quantitative structure-activity relationship (HQSAR); comparative molecular field analysis (CoMFA); comparative molecular similarity index analysis (CoMSIA); molecular modeling; active site; competitive inhibition; time-dependent inhibition (1)
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Articles 1 - 16 of 16
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Gamma Ray Flashes Produced By Lightning Observed At Ground Level By Tetra-Ii, D. J. Pleshinger, S. T. Alnussirat, J. Arias, S. Bai, Y. Banadaki, M. L. Cherry, Anderson Sunda-Meya
Gamma Ray Flashes Produced By Lightning Observed At Ground Level By Tetra-Ii, D. J. Pleshinger, S. T. Alnussirat, J. Arias, S. Bai, Y. Banadaki, M. L. Cherry, Anderson Sunda-Meya
Faculty and Staff Publications
In its first 2 years of operation, the ground-based Terrestrial gamma ray flash and Energetic Thunderstorm Rooftop Array (TETRA)-II array of gamma ray detectors has recorded 22 bursts of gamma rays of millisecond-scale duration associated with lightning. In this study, we present the TETRA-II observations detected at the three TETRA-II ground-level sites in Louisiana, Puerto Rico, and Panama together with the simultaneous radio frequency signals from the lightning data sets VAISALA Global Lightning Dataset, VAISALA National Lightning Detection Network, Earth Networks Total Lightning Network, andWorld Wide Lightning Location Network. The relative timing between the gamma ray events and the lightning …
The Association Of Infant Feeding Patterns With Food Allergy Symptoms And Food Allergy In Early Childhood, Joacy G. Mathias, Hongmei Zhang, Nelis Del C Soto-Ramirez, Willfried Karmaus
The Association Of Infant Feeding Patterns With Food Allergy Symptoms And Food Allergy In Early Childhood, Joacy G. Mathias, Hongmei Zhang, Nelis Del C Soto-Ramirez, Willfried Karmaus
Faculty and Staff Publications
Background: The role of infant feeding for food allergy in children is unclear and studies have not addressed simultaneous exposures to different foods. The goal of this study was to analyze existing data on feeding practices that represent realistic exposure and assess the risk of food allergy symptoms and food allergy in children.
Methods: The Infant Feeding Practices Study II conducted by the CDC and US-FDA enrolled pregnant women and collected infant feeding information using nine repeated surveys. Participants were re-contacted after 6 years. Food allergy data were collected at 4, 9, 12, and 72 months. In total, 1387 participants …
Precarious Work Schedules As A Source Of Economic Insecurity And Institutional Distrust, Susan J. Lambert, Julia R. Henly, Jaeseung Kim
Precarious Work Schedules As A Source Of Economic Insecurity And Institutional Distrust, Susan J. Lambert, Julia R. Henly, Jaeseung Kim
Faculty and Staff Publications
Work schedules may fuel precariousness among U.S. workers by undermining perceptions of security, both economic and societal. Volatile hours, limited schedule input, and short advance notice are all dimensions of precarious work schedules. Our analyses suggest that scheduling practices that introduce instability and unpredictability into workers’ lives undermine perceptions of security in unique ways for hourly and salaried workers. Although the data suggest that precarious scheduling practices are widespread in the labor market, workers who are black, young, and without a college degree appear to be at highest risk. The findings highlight the importance of examining constellations of scheduling practices …
The Effects Of Discipline Membership And Experience In The Field On Scholars’ Book And Journal Format Preferences, Ana Dubnjakovic
The Effects Of Discipline Membership And Experience In The Field On Scholars’ Book And Journal Format Preferences, Ana Dubnjakovic
Faculty and Staff Publications
Using data from Ithaka S + R US Faculty Survey 2015, the current study examined the influence of disciplinary differences and experience levels as well as their interactions on scholars’ attitudes toward print and electronic materials. While results of 3 × 5 factorial ANOVA procedure indicated both disciplinary membership and experience played a role in scholars’ attitudes, effect size indicated disciplinary membership played a more crucial role. Significant findings include rising popularity of electronic formats across examined groups.
Never-Ending Vacancies: Managing Capacity And Demand For Service, Emily K. Chan, Michelle Ornat
Never-Ending Vacancies: Managing Capacity And Demand For Service, Emily K. Chan, Michelle Ornat
Faculty and Staff Publications
No abstract provided.
An Overview Of Handheld Sun Photometer Measurements Of Atmospheric Aerosols In New Orleans, Louisiana: A Case Study Of The Xavier University Study Site., M. Bradley, B. Sevalia, M. Gasseller
An Overview Of Handheld Sun Photometer Measurements Of Atmospheric Aerosols In New Orleans, Louisiana: A Case Study Of The Xavier University Study Site., M. Bradley, B. Sevalia, M. Gasseller
Faculty and Staff Publications
Aerosol optical depth (AOT) was measured at Xavier University of Louisiana (XULA, 29.96ᵒ N, 90.11° W and 3m above sea level) using a GLOBE handheld sun photometer. The measurements were done at two different wavelengths, 505nm and 625nm. The measured values were used to extrapolate the AOT values for wavelengths 667nm, 551nm, 532nm and 490nm at the XULA site. The measured and calculated AOT values were then compared with values from the nearest AERONET station at Wave CIS site 6 (AERONET, 28.87ᵒ N, 90.48° W and 33m above sea level), which is 60 miles south of XULA. In this study …
Examining The Impact Of Victimization On Girls’ Delinquency: A Study Of Direct And Indirect Effects, Johanna Peterson, Dana Dehart, Emily Wright
Examining The Impact Of Victimization On Girls’ Delinquency: A Study Of Direct And Indirect Effects, Johanna Peterson, Dana Dehart, Emily Wright
Faculty and Staff Publications
Previous research has acknowledged that there is a relationship between victimization and later delinquency, but the specific attributes of this relationship are unclear because measures of both direct and indirect victimization are rarely explored in a single study. We included both indirect and direct victimization to examine which form of victimization was a stronger predictor of substance use, fighting, running away, and sex work among girls committed to a juvenile justice facility. Findings indicated that direct victimization was typically a more salient predictor of delinquency than indirect forms of victimization. Further, running away and sex work appear to be unique …
Examining The Impact Of Victimization On Girls’ Delinquency: A Study Of Direct And Indirect Effects, Johanna Peterson, Dana D. Dehart, Emily Wright
Examining The Impact Of Victimization On Girls’ Delinquency: A Study Of Direct And Indirect Effects, Johanna Peterson, Dana D. Dehart, Emily Wright
Faculty and Staff Publications
Previous research has acknowledged that there is a relationship between victimization and later delinquency, but the specific attributes of this relationship are unclear because measures of both direct and indirect victimization are rarely explored in a single study. We included both indirect and direct victimization to examine which form of victimization was a stronger predictor of substance use, fighting, running away, and sex work among girls committed to a juvenile justice facility. Findings indicated that direct victimization was typically a more salient predictor of delinquency than indirect forms of victimization. Further, running away and sex work appear to be unique …
Visualizing Success: Transforming Disparate Data Into A Dashboard That Tells A Story, Natasha Allen, Karen Schlesser, Micah Jeffries
Visualizing Success: Transforming Disparate Data Into A Dashboard That Tells A Story, Natasha Allen, Karen Schlesser, Micah Jeffries
Faculty and Staff Publications
In 2018, SJSU Library completed a project to revamp our public dashboard, incorporating data visualization best practices using Tableau. This session will focus on the step-by-step process of implementing this project, from the first stages to a successful debut. After some preliminary research, we began by creating a prototype and gathering feedback from stakeholders. Next we cleaned and extracted our data from Alma Analytics and other sources. We’ll talk about how we got our data into Tableau, including the pros and cons of using the Web Data Connector. Next we created our visualizations in Tableau. We’ll explain why we chose …
Coumarins And P450s, Studies Reported To-Date, Maryam Foroozesh, Jayalakshmi Sridhar, Navneet Goyal, Jiawang Liu
Coumarins And P450s, Studies Reported To-Date, Maryam Foroozesh, Jayalakshmi Sridhar, Navneet Goyal, Jiawang Liu
Faculty and Staff Publications
Cytochrome P450 enzymes (CYPs) are important phase I enzymes involved in themetabolism of endogenous and xenobiotic compounds mainly through mono-oxygenation reactions into more polar and easier to excrete species. In addition to their role in detoxification, they play important roles in the biosynthesis of endogenous compounds and the bioactivation of xenobiotics. Coumarins, phytochemicals abundant in food and commonly used in fragrances and cosmetics, have been shown to interact with P450 enzymes as substrates and/or inhibitors. In this review, these interactions and their significance in pharmacology and toxicology are discussed in detail.
The Pedagogy Of Design And Technology At Xavier University Of Louisiana, New Orleans, Shayna Tova Blum
The Pedagogy Of Design And Technology At Xavier University Of Louisiana, New Orleans, Shayna Tova Blum
Faculty and Staff Publications
Abstract. Xavier University of Louisiana (XULA) is a Science, Technology, Engineering, and Mathematics (STEM) university located in New Orleans, Louisiana. As a Historically Black University (HBCU), the university serves a diverse community of students in which many are first-generation, college graduates. Students enrolled in Design courses at XULA are studying in Bachelor of Science and Bachelor of Art programs and majoring in subjects such as Computer Science, Physics, Mass Communication, Art, Business, and Science. The interdisciplinary student environment offers a unique opportunity for collaboration and peer learning, whereby students are able to share diverse perspectives on a topic by relating …
Bias In Publishing? Gender Trends In Academic Library And Information Science Monograph Publications, Ngoc-Yen Tran, Erin Nevius
Bias In Publishing? Gender Trends In Academic Library And Information Science Monograph Publications, Ngoc-Yen Tran, Erin Nevius
Faculty and Staff Publications
For academic librarians, especially those in tenure-track positions, publishing is a necessity for tenure and promotion. While librarians and other information professionals publish in a number of formats, the publication of a scholarly monograph is undoubtably one of the highest levels of achievement and generally well regarded in the tenure and promotion process. As librarians, we understand that the monograph publication process and monograph publishers themselves can be skewed toward particular viewpoints and that these biases can limit the topics and types of items that are published, as well as who gets published. Although a lot of literature has been …
Lncegfl7os Regulates Human Angiogenesis By Interacting With Max At The Egfl7/Mir-126 Locus, Quinbo Zhou, Chastain Anderson, Zhan-Peng Huang, Jakub Hanus, Wensheng Zhang, Yu Han
Lncegfl7os Regulates Human Angiogenesis By Interacting With Max At The Egfl7/Mir-126 Locus, Quinbo Zhou, Chastain Anderson, Zhan-Peng Huang, Jakub Hanus, Wensheng Zhang, Yu Han
Faculty and Staff Publications
In an effort to identify human endothelial cell (EC)-enriched lncRNAs,~500 lncRNAswere shown to be highly restricted in primary human ECs. Among them,lncEGFL7OS, located inthe opposite strand of theEGFL7/miR-126gene, is regulated by ETS factors through abidirectional promoter in ECs. It is enriched in highly vascularized human tissues, and upregulatedin the hearts of dilated cardiomyopathy patients. LncEGFL7OS silencing impairs angiogenesis asshown by EC/fibroblast co-culture, in vitro/in vivo and ex vivo human choroid sproutingangiogenesis assays, while lncEGFL7OS overexpression has the opposite function. Mechanistically,lncEGFL7OS is required for MAPK and AKT pathway activation by regulating EGFL7/miR-126expression. MAX protein was identified as a lncEGFL7OS-interacting protein that …
Modernized Collaborations: Technologies Affecting Librarian Research Connections, Ngoc-Yen Tran, Emily K. Chan
Modernized Collaborations: Technologies Affecting Librarian Research Connections, Ngoc-Yen Tran, Emily K. Chan
Faculty and Staff Publications
There is no doubt that now, more than ever, technologies have made it easier for library researchers to connect and collaborate with one another. The increase in adoption and use of cloud-based products that support group work in higher education (such as the G Suite for Education) have also encouraged the collaborative nature of library and information science (LIS) research and publications.
In our presentation, we will present the results of our study in identifying the methods by which librarians find collaborators for research projects. Employing a mixed methods study, we collected survey data from librarians on the tools and …
Transactivation Of Human Endogenous Retroviruses By Tumor Viruses And Their Functions In Virus-Associated Malignancies., Jungang Chen, Maryam Foroozesh, Zhiqiang Qin
Transactivation Of Human Endogenous Retroviruses By Tumor Viruses And Their Functions In Virus-Associated Malignancies., Jungang Chen, Maryam Foroozesh, Zhiqiang Qin
Faculty and Staff Publications
Human endogenous retroviruses (HERVs), viral-associated sequences, are normal components of the human genome and account for 8–9% of our genome. These original provirus sequences can be transactivated to produce functional products. Several reactivated HERVs have been implicated in cancers and autoimmune diseases. An emerging body of literature supports a potential role of reactivated HERVs in viral diseases, in particular viral-associated neoplasms. Demystifying studies on the mechanism(s) of HERV reactivation could provide a new framework for the development of treatment and prevention strategies targeting virus-associated tumors. Although available data suggest that coinfection by other viruses, such as Kaposi’s Sarcoma-associated herpesvirus (KSHV) …
Examining Good-Game Design Mechanics That Enhance Student Motivation: A Case Study Of “The Research Race” Game, Ngoc-Yen Tran
Examining Good-Game Design Mechanics That Enhance Student Motivation: A Case Study Of “The Research Race” Game, Ngoc-Yen Tran
Faculty and Staff Publications
The Research Race (hereon referred to simply as The Race) is an active learning game played in one-shot information literacy sessions. It is an exercise that has students working together in teams to find answers and to locate materials in a friendly competition with their classmates, while also introducing them to the physical and digital spaces of the library. This chapter outlines how to play The Race and gives rationale for how The Race can enhance motivation through the use of good game design mechanics.